Hi-C Newswire

Comprehensive Real-Time News Feed for Hi-C.

Results 1 - 20 of 74 in Hi-C

  1. A 3D Map of the Human Genome at Kilobase Resolution Reveals Principles of Chromatin LoopingRead the original story

    14 hrs ago | CiteULike

    To insert individual citation into a bibliography in a word-processor, select your preferred citation style below and drag-and-drop it into the document. We use in situ Hi-C to probe the 3D architecture of genomes, constructing haploid and diploid maps of nine cell types.

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  2. runHiC 0.1.2Read the original story

    Yesterday | Python

    runHiC is a easy-to-use Hi-C processing software based on hiclib ( https://bitbucket.org/mirnylab/hiclib ) [1] . Different from hiclib, which was born for flexibility, runHiC is a customized pipeline, and can be run from command line directly. runHiC ...

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  3. runHiC 0.1.0Read the original story

    Wednesday | Python

    runHiC is a easy-to-use Hi-C processing software based on hiclib ( https://bitbucket.org/mirnylab/hiclib ) [1] . Different from hiclib, which was born for flexibility, runHiC is a customized pipeline, and can be run from command line directly. runHiC ...

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  4. HIPPIE: a high-throughput identification pipeline for promoter interacting enhancer elements.Read the original story

    Monday Dec 22 | CiteULike

    We implemented a high-throughput identification pipeline for promoter interacting enhancer element to streamline the workflow from mapping raw Hi-C reads, identifying DNA-DNA interacting fragments with high confidence and quality control, detecting histone modifications and DNase hypersensitive enrichments in putative enhancer elements, to ultimately extracting possible intra- and inter-chromosomal enhancer-target gene relationships. Availability and implementation: This software package is designed to run on high-performance computing clusters with Oracle Grid Engine.

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  5. Function Follows Form: A New Look at Genome FoldingRead the original story

    Friday Dec 19 | Bio IT World

    ... of the nucleus in a new way, which gave them a clearer view of what was going on. They used a new version of the Hi-C protocol, originally published by Erez Lieberman Aiden in 2009, to comprehensively map chromatin contacts genome-wide (see, New ...

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  6. What 200 Calories of Every Christmas Food Looks LikeRead the original story w/Photo

    Friday Dec 19 | The Atlantic

    ... are the Grinch. For those of us not from the Continent, 142 milliliters is less than 5 ounces, which is less than a Hi-C juice box. You'd better not pout! Cooking for yourself is one of the surest ways to eat well. Bestselling author Mark Bittman ...

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  7. A 3D Map of the Human Genome at Kilobase Resolution Reveals Principles of Chromatin LoopingRead the original story

    Friday Dec 19 | CiteULike

    To insert individual citation into a bibliography in a word-processor, select your preferred citation style below and drag-and-drop it into the document. We use in situ Hi-C to probe the 3D architecture of genomes, constructing haploid and diploid maps of nine cell types.

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  8. The Hitchhiker's guide to Hi-C analysis: Practical guidelines.Read the original story

    Wednesday Dec 17 | CiteULike

    ... of this paper is to provide guidelines for analyzing and interpreting data obtained with genome-wide 3C methods such as Hi-C and 3C-seq that rely on deep sequencing to detect and quantify pairwise chromatin interactions genome-wide. Copyright ...

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  9. 3D maps reveal 'genomic origami'Read the original story

    Monday Dec 15 | Newkerala.com

    ... way of thinking about how cells work," Rao added. For the study, the researchers used a technology called "in situ Hi-C" to collect billions of snippets of DNA that were later analysed for signs of loops. "Our maps of looping have revealed thousands ...

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  10. 3-D maps reveal the genome's origami codeRead the original story w/Photo

    Wednesday Dec 3 | R & D

    ... in close contact in the folded version of the genome in a cell's nucleus. Researchers used a technology called "in situ Hi-C" to collect billions of snippets of DNA that were later analyzed for signs of loops. The team found that loops and other ...

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  11. A 3D Map of the Human Genome at Kilobase Resolution Reveals Principles of Chromatin LoopingRead the original story

    Sunday Dec 14 | CiteULike

    To insert individual citation into a bibliography in a word-processor, select your preferred citation style below and drag-and-drop it into the document. We use in situ Hi-C to probe the 3D architecture of genomes, constructing haploid and diploid maps of nine cell types.

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  12. 3D map of DNA reveals hidden loops that allow genes to work togetherRead the original story w/Photo

    Thursday Dec 11 | Science

    ... now at Baylor College of Medicine (BCM) in Houston, Texas, and his colleagues came up with a method they called Hi-C to look at all the connections at once. They couldn't see much detail-only down to a million-base resolution, many times larger than ...

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  13. TADLib 0.1.0Read the original story

    Friday Nov 28 | Python

    Chromosome conformation capture derived techniques, especially Hi-C, have revealed that topologically associating domain is a structural basis for both chromatin organization and regulation in three-dimensional space. To systematically investigate the relationship between structure and function, it is important to develop a quantitative parameter to measure the structural characteristics of TAD.

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  14. Comprehensive Mapping of Long-Range Interactions Reveals Folding Principles of the Human GenomeRead the original story

    Wednesday Nov 26 | CiteULike

    To insert individual citation into a bibliography in a word-processor, select your preferred citation style below and drag-and-drop it into the document. We describe Hi-C, a method that probes the three-dimensional architecture of whole genomes by coupling proximity-based ligation with massively parallel sequencing.

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  15. Topologically associating domains are stable units of replication-timing regulationRead the original story

    Wednesday Nov 26 | CiteULike

    ... open and closed three-dimensional chromatin compartments identified by high-resolution chromosome conformation capture (Hi-C), and, to a lesser extent, late replication correlates with lamina-associated domains (LADs). Recent Hi-C mapping has ...

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  16. Topologically associating domains are stable units of replication-timing regulationRead the original story

    Nov 19, 2014 | Nature

    ... open and closed three-dimensional chromatin compartments identified by high-resolution chromosome conformation capture (Hi-C), and, to a lesser extent, late replication correlates with lamina-associated domains (LADs) 4 , 5 , 8 , 9 . Recent Hi-C ...

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  17. Distance-based assessment of the localization of functional annotations in 3D genome reconstructionsRead the original story

    Nov 18, 2014 | BioMed Central

    Recent studies used the contact data or three-dimensional genome reconstructions from Hi-C to assess the co-localization of functional genomic annotations in the nucleus. These analyses dichotomized data point pairs belonging to a functional annotation as "close" or "far" based on some threshold and then tested for enrichment of "close" pairs.

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  18. Msi GTX 970 Gaming 4G ReviewRead the original story

    Nov 17, 2014 | Overclockers Club

    ... push the airflow through the heat sink quietly. A custom PCB is equipped with MSI's Military spec components, including Hi-C caps, Super Ferrite chokes, and solid capacitors that provide a cooler, more efficient voltage regulation circuit all in the ...

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  19. Chromatin Loops as Allosteric Modulators of Enhancer-Promoter InteractionsRead the original story

    Nov 3, 2014 | CiteULike

    ... is crucial for a full understanding of gene expression. Recent experimental mapping of chromosomal interactions by the Hi-C method shows an intricate network of local looping interactions surrounding enhancers and promoters. We model a region of ...

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  20. Manteno Rotary To Host Pancake DinnerRead the original story

    Oct 29, 2014 | Manteno News

    ... beginning of October. The ticket is good for all the pancakes you can eat, plus one order of sausage, coffee, milk or Hi-C orange drink. The tickets will be pre-sold for $50; no tickets are allowed to be purchased at the door. Tickets are available ...

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