Atherosclerosis Newswire

Comprehensive Real-Time News Feed for Atherosclerosis.

Results 1 - 20 of 62 in Atherosclerosis

  1. Gene Therapy for Hypercholesterolemia: Sweet Dreams and Flying Machines [Editorials]Read the original story

    20 hrs ago | Circulation

    ... Untreated FH heterozygotes have plasma LDL cholesterol levels 2A- to 3A- normal and begin to express atherosclerosis symptoms and signs in the third to fourth decade of life. FH heterozygotes respond well to multidimensional treatment, including ...

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  2. Amgen Announces Positive Top-Line Results From Phase 3 YUKAWA-2 Trial ...Read the original story

    Yesterday | Applied Clinical Trials

    ... and efficacy of evolocumab in 404 Japanese patients with high cardiovascular risk based on the Japan Atherosclerosis Society guidelines9 and with hyperlipidemia or mixed dyslipidemia (LDL-C 100 mg/dL). Patients were randomized to one of eight ...

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  3. Amgen's Cholesterol Lowering Drug Succeeds In Phase 3 TrialRead the original story

    Yesterday | BioSpace

    ... and efficacy of evolocumab in 404 Japanese patients with high cardiovascular risk based on the Japan Atherosclerosis Society guidelines9 and with hyperlipidemia or mixed dyslipidemia (LDL-C 100 mg/dL). Patients were randomized to one of eight ...

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  4. LincRNA-p21 Regulates Neointima Formation, Vascular Smooth Muscle...Read the original story

    Monday Aug 25 | Circulation

    Long non-coding RNAs (lncRNAs) recently have been implicated in many biological processes and diseases. Atherosclerosis is a major risk factor for cardiovascular disease. However, the functional role of lncRNAs in atherosclerosis is largely unknown. ...

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  5. Coenzyme Q10 Increases Cholesterol Efflux and Inhibits Atherosclerosis Through MicroRNAs [Editorials]Read the original story

    Wednesday Aug 20 | Circulation

    ... of Medicine, Vanderbilt University School of Medicine, 2220 Pierce Ave 312B PRB, Nashville, TN 37232. E-mail Atherosclerosis is a progressive inflammatory disease of the artery wall and the underlying basis for cardiovascular disease (CVD), which ...

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  6. Contribution of Homeostatic Chemokines CCL19 and CCL21 and Their...Read the original story

    Wednesday Aug 20 | Circulation

    ... disease in a Chinese Han population. Approach and Results- Immunohistochemical analysis of samples with atherosclerosis of various stages showed increased CCL19, CCL21, and CCR7 expression in atherosclerotic coronary plaques compared with ...

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  7. Doctor recommended treatment options for atherosclerosisRead the original story w/Photo

    Thursday Aug 14 | Examiner.com

    Treatments for atherosclerosis vary according to the severity of the problem. Your doctor can tell you what options suit your situation best.

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  8. Rosuvastatin Activates ATP-Binding Cassette Transporter A1-Dependent...Read the original story

    Thursday Aug 7 | Circulation

    ... verse cholesterol transport, and this finding highlights the potential of rosuvastatin for the regression of atherosclerosis.

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  9. How to manage high cholesterol levels naturally?Read the original story w/Photo

    Friday Aug 1 | PRWeb

    ... blood vessels and stops blood flowing properly. Eventually the plaque hardens arteries, a condition called atherosclerosis. It is important to keep LDL cholesterol levels low as high levels can make sufferers more likely to have a heart attack or a ...

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  10. Metformin enhances nitric oxide production and diminishes Rho Kinase...Read the original story

    Jul 15, 2014 | Lipids in Health and Disease

    Rho kinase over-activation is associated with nitric oxide reduction and atherosclerosis.

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  11. Role of Flow-Sensitive microRNAs in Endothelial Dysfunction and...Read the original story

    Jul 10, 2014 | Circulation

    ... and Emory University, 1760 Haygood Dr, Health Science Research Bldg, E-170, Atlanta, GA 30322. Email Atherosclerosis preferentially occurs in arterial regions exposed to disturbed flow, in part, due to alterations in gene expression. MicroRNAs ...

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  12. Contribution of Homeostatic Chemokines CCL19 and CCL21 and Their...Read the original story

    Jul 2, 2014 | Circulation

    ... disease in a Chinese Han population. Approach and Results- Immunohistochemical analysis of samples with atherosclerosis of various stages showed increased CCL19, CCL21, and CCR7 expression in atherosclerotic coronary plaques compared with ...

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  13. Adiponectin: a manifold therapeutic target for metabolic syndrome, diabetes, and coronary disease?Read the original story

    Jun 23, 2014 | Cardiovascular Diabetology

    ... between coronary artery disease (CAD) and alterations in glucose metabolism has raised the likelihood that atherosclerosis and type 2 diabetes mellitus (T2DM) may share a common biological background. We summarize here the current knowledge about ...

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  14. Resverlogix Places a Bet On RVX-208Read the original story

    Jun 4, 2014 | Seeking Alpha

    ... RVX.TO, offers some minimal additional liquidity.) Cholesterol lowering drugs aimed at prevention of atherosclerosis are among the best selling drugs ever, with annual sales of Lipitor (before the drug went off patent) peaking at 10+ billion dollars ...

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  15. Cigna Customers Prescribed CRESTOR May Lower Their Bad Cholesterol with Reduced Out-of-Pocket CostsRead the original story

    Jun 2, 2014 | WebWire

    ... HDL-C in adult patients with primary hyperlipidemia or mixed dyslipidemia and to slow the progression of atherosclerosis in adult patients as part of a treatment strategy to lower Total-C and LDL-C to target levels. CRESTOR is also indicated to ...

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  16. Epigenetic changes and atherosclerosis a result of disturbance in blood flowRead the original story

    May 29, 2014 | Medical News Today

    Disturbed patterns of blood flow induce lasting epigenetic changes to genes in the cells that line blood vessels, and those changes contribute to atherosclerosis , researchers have found.

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  17. Extravascular Optical Coherence Tomography: Evaluation of Carotid...Read the original story

    Mar 24, 2014 | Circulation

    ... as a noninvasive imaging methodology with micrometer resolution, was evaluated in a murine model of carotid atherosclerosis by way of assessing the efficacy of pravastatin therapy. Methods- An OCT device was engineered for extravascular plaque ...

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  18. Disturbance in blood flow leads to epigenetic changes, atherosclerosisRead the original story w/Photo

    May 27, 2014 | Science Daily

    Disturbed patterns of blood flow induce lasting epigenetic changes to genes in the cells that line blood vessels, and those changes contribute to atherosclerosis, researchers have found.

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  19. Systematic study of the effects of lowering low-density...Read the original story

    May 2, 2014 | BioMed Central

    ... accepted that high serum concentrations of low-density lipoprotein cholesterol (LDL-C) can lead to atherosclerosis and accelerate the progression of atherosclerosis which is main causes of coronary artery disease [ 1 ]. Disruption of coronary ...

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  20. Effects of Fenofibric Acid on Carotid Intima-Media Thickness in...Read the original story

    May 14, 2014 | Circulation

    From the Department of Medicine, University of Chicago, IL ; Icahn School of Medicine at Mount Sinai, New York, NY ; Biofortis Clinical Research, Addison, IL ; Cardiology, University of Adelaide, Adelaide, Australia ; Consultant Cardiologist, Royal Adelaide Hospital, Adelaide, Australia ; Section of Cardiology, Section of Atherosclerosis and ... (more)

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