Salsalate (generic), Disalcid, Salflex Newswire

Salsalate (generic), Disalcid, Salflex Newswire

Comprehensive Real-Time News Feed for Salsalate (generic), Disalcid, Salflex.

Results 1 - 20 of 26 in Salsalate (generic), Disalcid, Salflex

  1. Drug discovery paradigm targets Tau protein aggregation linked to the Alzheimer's diseaseRead the original story w/Photo

    Feb 26, 2016 | PhysOrg Weblog

    Dementia and other tauopathies, most notably Alzheimer's disease, embody a class of neurodegenerative diseases associated with the aggregation of the Tau protein in the human brain. These diseases represent one of the leading causes of death and disability in the elderly population in the western world, with no current effective therapy.

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  2. Research reveals connection between tauopathies and disruption in protein synthesisRead the original story w/Photo

    Jan 20, 2016 | PhysOrg Weblog

    Assistant Professor Joe Abisambra, researcher at the University of Kentucky Sanders-Brown Center on Aging, has demonstrated for the first time that tau impairs protein synthesis-a key component in memory loss. "Though the exact mechanisms leading to memory loss in tauopathies are not yet known, the scientific community has acknowledged for years that in Alzheimer's disease brains, tau associates with ribosomes, the hub of protein production.

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  3. Traumatic brain injury induces mental impairments using mechanisms linked with Alzheimer'sRead the original story w/Photo

    Jan 12, 2016 | PhysOrg Weblog

    A new study from The University of Texas Medical Branch at Galveston fills an important gap in understanding the link between traumatic brain injury and neurodegenerative disorders such as Alzheimer's disease. Previously, UTMB researchers found a toxic form of tau protein that increases after a traumatic brain injury that may contribute to development of chronic traumatic encephalopathy , a condition experienced by many professional athletes and military personnel.

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  4. No increased dementia risk found in diagnosed celiac patientsRead the original story w/Photo

    Oct 19, 2015 | PhysOrg Weblog

    A new and comprehensive study by investigators at the Celiac Disease Center at Columbia University Medical Center has found that celiac patients are at no increased risk for dementia before or after their diagnosis of celiac disease. "Patients coming to our center have long described 'brain fog,' and it appears that gluten can cause cognitive effects in some individuals with and without celiac disease," said Peter Green, MD, the Phyllis and Ivan Seidenberg Professor of Medicine at Columbia University and the director of the Celiac Disease Center.

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  5. Dietary interventions can improve memory performance for diseases like Alzheimer'sRead the original story w/Photo

    Oct 14, 2015 | PhysOrg Weblog

    Dietary supplementation could play a crucial role in keeping Europe's ageing population healthy, an EU-funded study has confirmed. The LIPIDIDIET project, which was completed in March 2015, demonstrated that women susceptible to Alzheimer's disease lose weight more sharply after the age of 70, whether they go on to develop dementia or not.

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  6. Healthy diet may reduce cognitive decline as people ageRead the original story w/Photo

    Oct 13, 2015 | PhysOrg Weblog

    Eating healthier may reduce cognitive decline and diminish the negative impact of an unhealthy diet on memory and thinking abilities in older adults, suggests a new study by researchers at Karolinska Institutet. The findings are being published online by the journal Alzheimer's & Dementia.

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  7. New drug candidate ameliorates Alzheimer's and other brain diseasesRead the original story w/Photo

    Oct 13, 2015 | PhysOrg Weblog

    Professor Armin Giese from the Center for Neuropathology and Prion Research at the LMU Munich and researchers at the Max Planck Institute for Biophysical Chemistry in Gottingen and at the German Center for Neurodegenerative Diseases in Bonn have analyzed a novel substance that could serve as a prototype for the development of drugs to treat Alzheimer's and other brain diseases. Known as "anle138b", this substance ameliorated disease symptoms in mice and improved their cognition.

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  8. Best and Worst of Health and Healthcare - September 2015Read the original story

    Oct 10, 2015 | GNIF Brain Blogger

    Last month was highly prolific in Alzheimer's disease research - pathological mechanisms were described, detection tools were evaluated, and therapeutic targets were unraveled. But it was not all about Alzheimer's.

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  9. Researchers discover role of microglia during early progression of Alzheimer's diseaseRead the original story w/Photo

    Oct 5, 2015 | PhysOrg Weblog

    For the first time, researchers have determined how toxic tau fibrils spread by the help of brain immune cells called microglia during the early stages of Alzheimer's disease . The discovery of this new pathway may lead to a therapeutic target for AD, one that has not been previously identified.

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  10. Disruption of brain-blood barrier might influence progression of Alzheimer'sRead the original story w/Photo

    Sep 29, 2015 | PhysOrg Weblog

    More and more data from preclinical and clinical studies strengthen the hypothesis that immune system-mediated actions contribute to and drive pathogenesis in Alzheimer's disease. The team of Roosmarijn Vandenbroucke in the Claude Libert Group combined their knowledge and expertise related to inflammation with the expertise in Alzheimer's disease present in the Bart De Strooper Group .

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  11. Researchers quantify relationship between scientific discoveries and advances in medicineRead the original story w/Photo

    Sep 24, 2015 | PhysOrg Weblog

    Scientists from the Gladstone Institutes have provided a detailed map of how basic research translates into new treatments for deadly diseases. Charting the network of discoveries that led to the development of important therapeutic drugs, the investigators revealed that, up to now, the path to a cure has required thousands of scientists and many decades.

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  12. Arthritis Medication Salsalate May Help Prevent Alzheimer'sRead the original story w/Photo

    Sep 23, 2015 | News Max

    The arthritis medication salsalate may be effective in helping fight off Alzheimer's disease, according to a recent study published in the science journal Nature Medicine. Salsalate is a prescription medication currently used for the treatment of rheumatoid arthritis, but the study conducted at Gladstone Institutes in San Francisco found the drug could prevent the accumulation of protein tau, reported Medical News Today .

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  13. Old Drug Offers New Hope for Alzheimer'sRead the original story w/Photo

    Sep 23, 2015 | News Max

    A drug used to treat rheumatoid arthritis could offer a treatment for Alzheimer's disease, a preliminary study shows. Scientists from the Gladstone Institutes at University of California-San Francisco say they have discovered that salsalate, a drug used to treat rheumatoid arthritis, effectively lowers tau protein levels in mice.

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  14. Drug may reverse dementiaRead the original story w/Photo

    Sep 22, 2015 | The New Zealand Herald

    Trials limited to mice could soon include humans because researchers know the drug is safe and produces few side-effects. Photo / iStock A drug brought to light by Hippocrates in the 5th century BC could help restore memory in Alzheimer's patients, scientists hope.

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  15. Old drug offers new hope to treat Alzheimer's diseaseRead the original story w/Photo

    Sep 22, 2015 | Medical News Today

    Scientists from the Gladstone Institutes have discovered that salsalate, a drug used to treat rheumatoid arthritis , effectively reversed tau-related dysfunction in an animal model of frontotemporal dementia . Salsalate prevented the accumulation of tau in the brain and protected against cognitive impairments resembling impairments seen in Alzheimer's disease and FTD.

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  16. Existing arthritis drug bodes well for Alzheimer'sRead the original story w/Photo

    Sep 22, 2015 | Medical News Today

    An existing prescription drug may be able to help in the fight against Alzheimer's, according to research published in Nature Medicine. A study at the Gladstone Institutes in San Francisco, CA, has found that salsalate, already established as a treatment for rheumatoid arthritis , is able to prevent the accumulation of the protein tau - known to cause toxicity and contribute to cognitive degeneration.

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  17. Combination drug treatment reduces agitation for patients with probable Alzheimer's diseaseRead the original story w/Photo

    Sep 22, 2015 | PhysOrg Weblog

    In a preliminary 10-week randomized trial, patients with probable Alzheimer disease who received the combination medication dextromethorphan-quinidine demonstrated less occurrences and severity of agitation, compared to patients who received placebo, according to a study in the September 22/29 issue of JAMA . Agitation and aggression are highly prevalent in patients with dementia and are associated with distress for patients and caregivers, greater risk of institutionalization, and accelerated progression to severe dementia and death.

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  18. Drug found 2400 years ago could restore memory Alzheimer's patientsRead the original story w/Photo

    Sep 22, 2015 | Sydney Morning Herald

    A drug brought to light by Hippocrates in the 5th century BC could help restore memory in Alzheimer's patients, scientists hope. Salsalate, which comes from the same family as aspirin, was typically used to treat inflammatory conditions such as rheumatoid arthritis.

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  19. Increased chances for early detection of Alzheimer's diseaseRead the original story w/Photo

    Sep 22, 2015 | PhysOrg Weblog

    A method for detecting early signs of Alzheimer's disease using amyloid PET imaging works as well as the previously used cerebrospinal fluid sample method. This is the conclusion of a new Lund University study-the most thorough and extensive undertaken in the field so far.

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  20. Secret behind Alzheimer's cure may be found in old arthritis drug, scientists claimRead the original story w/Photo

    Sep 22, 2015 | Mirror.co.uk

    A drug that was previously used to treat rheumatoid arthritis is offering experts hope in the fight against Alzheimer's and other forms of dementia. The anti-inflammatory drug salsalate has been found to prevent damage to the brain associated with the diseases and reversed memory loss following tests on laboratory mice with frontotemporial dementia.

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