
Results 1 - 20 of 38 in Lamivudine (generic), Epivir, Epivir-HBV
Statin and Diabetes Drug Show Activity against Hepatitis B Virus in Laboratory Studies
SUMMARY: Simvastatin , a medication used to lower blood cholesterol, had a synergistic effect against hepatitis B virus when combined with antiviral drugs in a laboratory study, researchers reported last month at the 60th Annual Meeting of the American Association for the Study of Liver Diseases in Boston. Comment?
Burcon announces appointment of a new director and patent grants
D. Lorne Tyrrell to its board of directors. D. Lorne Tyrrell is the Canadian Institute of Health Research /Glaxo SmithKline Chair in Virology in the Department of Medical Microbiology and Immunology at the University of Alberta. Comment?
Findings on viral rebound discourage quick drug switches in resource-limited settings
A South African study found that viral resuppression occurred in 41% of people who continued taking the same antiretroviral drug regimen after experiencing a viral load increase on treatment. Comment?
Tenofovir (Viread) Produces Good HBV Suppression in Chronic Hepatitis ...
Tenofovir Produces Good HBV Suppression in Chronic Hepatitis B Patients with Resistance to Adefovir SUMMARY: Nucleoside/nucleotide analogs are highly effective against HBV , but the virus can evolve to become resistant to the drugs, especially when used as monotherapy. Comment?
Long-term Data Show Telbivudine (Tyzeka) Suppresses HBV Viral Load...
Long-term Data Show Telbivudine Suppresses HBV Viral Load and Leads to HBeAg Clearance in Chronic Hepatitis B Patients SUMMARY: At the 60th Annual Meeting of the American Association for the Study of Liver Diseases this month in Boston, researchers reported 4-year data from the GLOBE study, indicating that the nucleoside analog telbivudine ... Comment?
Early HBsAg Decline Predicts Sustained Response to Pegylated...
SUMMARY: Chronic hepatitis B patients who experience an early decrease in hepatitis B surface antigen starting before week 24 of therapy are more likely to achieve sustained response to pegylated interferon alfa-2a , according to an analysis presented at the 60th Annual Meeting of the American Association for the Study of Liver Diseases this month ... Comment?
Review Finds Pegylated Interferon Is More Effective than Lamivudine...
SUMMARY: A systemic review of clinical trials found that pegylated interferon was more effective than the oral antiviral drug lamivudine at achieving endpoints including hepatitis B virus DNA clearance and hepatitis B "e" antigen seroconversion, investigators reported at the 60th Annual Meeting of the American Association for the Study of Liver ... Comment?
Alledged Fort Hood Shooter Left Behind an Old Bottle of Combivir
In a shoe box filled with vitamins and prescription medications, the alledged Fort Hood shooter Major Nidal Malik Hasan had a bottle of the HIV medication Combivir . Comment?
Tenofovir (Viread) Regimens Are Effective and Well-tolerated in...
Tenofovir Regimens Are Effective and Well-tolerated in Chronic Hepatitis B Patients with Decompensated Liver Disease SUMMARY: The nucleotide analog tenofovir , especially when combined with emtricitabine -- the 2 drugs in the Truvada coformulation -- was well-tolerated and produced good hepatitis B virus suppression and hepatitis B "e" antigen loss ... Comment?
BARACLUDE(R) (entecavir) Demonstrated Greater Antiviral Efficacy...
BARACLUDE Demonstrated Greater Antiviral Efficacy Compared To Adefovir In New Study Of Chronic Hepatitis B Patients With Cirrhosis Main Category: Liver Disease / Hepatitis Article Date: 03 Nov 2009 - 4:00 PST Bristol-Myers Squibb today announced 48-week data from an ongoing study of chronic hepatitis B patients with decompensated cirrhosis, in ... Comment?
Tenofovir (Viread) Suppresses HBV Viral Load Long-term in HIV/HBV...
Tenofovir Suppresses HBV Viral Load Long-term in HIV/HBV Coinfected Patients, but Kidney Function May Decline SUMMARY: HIV/HBV coinfected individuals treated with agents that are dually active against both virus experience rapid suppression of hepatitis B virus , and about 15% of those taking tenofovir plus emtricitabine achieve hepatitis B "e" ... Comment?
Entecavir (Baraclude) Demonstrates Greater Antiviral Activity than...
Entecavir Demonstrates Greater Antiviral Activity than Adefovir in Hepatitis B Patients with Decompensated Liver Disease SUMMARY: Entecavir exhibited greater antiviral activity against hepatitis B virus than adefovir in patients with decompensated liver cirrhosis, and was associated with clinical benefits including improved survival, according to a ... Comment?
Long-term Studies Show Tenofovir (Viread) Safety and Efficacy Is...
Long-term Studies Show Tenofovir Safety and Efficacy Is Sustained at 3 Years in HBeAg Positive and Negative Hepatitis B Patients SUMMARY: Long-term follow-up data from 2 clinical trials show that tenofovir remained active against hepatitis B virus and was generally well-tolerated for up to 3 years, researchers reported this past weekend at the 60th ... Comment?
Patients with hepatitis B virus genotypes E, F, G, and H appear to be sensitive to interferon alpha, as well as nucleoside/nucleotide analogs, although sustained virological response rates did not exceed 50%, according to a report in the October 2009 issue of the Journal of Medical Virology . Comment?
Avexa Closes Trial of Experimental NRTI Apricitabine, Will Evaluate 24-week Data
Avexa recently announced that it will close a Phase 3 study of its investigational nucleoside reverse transcriptase inhibitor candidate apricitabine, and will analyze 24-week data ahead of schedule. Comment?
Most Patients with Low Baseline HBV Viral Load Can Safely Discontinue ...
Most Patients with Low Baseline HBV Viral Load Can Safely Discontinue Lamivudine after Achieving Virological Suppression Most chronic hepatitis B patients with low pre-treatment HBV DNA levels with pre-treatment HBV DNA < 10 8 copies/mL. This difference in cumulative relapse rates between the 2 groups was statistically significant . Comment?
Resistance to Hepatitis B Drugs is Common among HIV/HBV Coinfected...
The material posted on HIV and Hepatitis.com about the 49th ICAAC is not approved by the American Society for Microbiology Resistance to Hepatitis B Drugs is Common among HIV-HBV Coinfected Patients Receiving Lamivudine-containing ART without Tenofovir Resistance to the hepatitis B drugs adefovir , entecavir , and telbivudine is common among ... Comment?
Current management of Hep B before and after liver transplantation
The most recent issue of Liver Transplantation investigates current management of hepatitis B virus infection before and after liver transplantation. Comment?
HIV-HBV Coinfected Patients Respond to Antiretroviral Therapy as well ...
HIV positive people coinfected with hepatitis B virus respond as well to combination antiretroviral therapy as individuals with HIV alone, but they are more likely to die due to non-AIDS-related causes, according to a study published in the September 10, 2009 issue of AIDS . Comment?
Abacavir (Ziagen) Backbone Suppresses HIV as well as Tenofovir (Viread) in Uk Chic Study
Patients who used abacavir as part of their first combination antiretroviral regimen experienced early HIV suppression similar to that of patients taking tenofovir -- regardless of initial viral load -- and the groups had similar low rates of virological failure at 48 weeks, according to a recent British study. Comment?