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Correspondence: Dr C-D Hu, Department of Medicinal Chemistry and Molecular Pharmacology, Purdue University, 575 Stadium Mall Dr., West Lafayette, IN 47907, USA. E-mail: [email protected] Protein arginine methyltransferase 5 is an emerging epigenetic enzyme that mainly represses transcription of target genes via symmetric dimethylation of arginine residues on histones H4R3, H3R8 and H2AR3. Comment?
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