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These are high magnification images representing immunochemistry of IL-33 , Iba1 , and GFAP in the central retina of a control eye and lesion and nonlesion areas of an AMD eye. The bright-field images show RPE loss in the AMD lesion site. Comment?
The red-stained cells in the frame on the left do not express the axon-repelling protein NELL2, but the red cells in the frame on the right do. Credit: Alexander Jaworski/Brown University It's a wonder of nature - and a darned good thing - that amid many billions of similar cells in the brain and spinal cord, neurons can extend their tendrillous axons to exactly the right place to form connections. Comment?
Drugmaker Bristol-Myers Squibb is expanding its partnership with Five Prime Therapeutics to develop that company's antibody-based drug candidates into medicines for cancer and other conditions. Bristol-Myers is a leader in the hot field of immuno-oncology, which involves drugs that stimulate the body's immune system to spot and attack tumor cells that otherwise could evade detection. Comment?
Even after the advent of powerful medications for suppressing HIV, a new study finds that more than one-third of people in San Francisco who were diagnosed with an AIDS-related infection died within five years. "The main cause of mortality arises from people stopping treatment entirely," said Dr. Robert Grant, a professor at the University of California, San Francisco, who reviewed the findings but was not involved in the research. Comment?
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