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These are high magnification images representing immunochemistry of IL-33 , Iba1 , and GFAP in the central retina of a control eye and lesion and nonlesion areas of an AMD eye. The bright-field images show RPE loss in the AMD lesion site. Comment?
The red-stained cells in the frame on the left do not express the axon-repelling protein NELL2, but the red cells in the frame on the right do. Credit: Alexander Jaworski/Brown University It's a wonder of nature - and a darned good thing - that amid many billions of similar cells in the brain and spinal cord, neurons can extend their tendrillous axons to exactly the right place to form connections. Comment?
Drugmaker Bristol-Myers Squibb is expanding its partnership with Five Prime Therapeutics to develop that company's antibody-based drug candidates into medicines for cancer and other conditions. Bristol-Myers is a leader in the hot field of immuno-oncology, which involves drugs that stimulate the body's immune system to spot and attack tumor cells that otherwise could evade detection. Comment?
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