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Loss of muscle volume is a common and often debilitating outcome of traumatic orthopedic injury, resulting in muscle weakness and suboptimal limb function. A new therapeutic approach in which small pieces of autologous muscle can be expanded in a collagen hydrogel and used to regenerate functional muscle at the sight of injury, instead of relying on a donor muscle graft, would be especially beneficial for repairing large areas of muscle loss. Comment?
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