Cold Spring Harbor Newswire

Cold Spring Harbor Newswire

Comprehensive Real-Time News Feed for Cold Spring Harbor, NY.

Results 1 - 20 of 42 for "u:eurekalert.org" in Cold Spring Harbor, NY

  1. More tomatoes, faster: Accelerating tomato engineeringRead the original story w/Photo

    12 hrs ago | EurekAlert!

    Tomatoes are already an ideal model species for plant research, but scientists at the Boyce Thompson Institute just made them even more useful by cutting the time required to modify their genes by six weeks. While looking for ways to make tomatoes and other crop plants more productive, BTI Assistant Professor Joyce Van Eck and former postdoctoral scientist Sarika Gupta developed a better method for "transforming" a tomato--a process that involves inserting DNA into the tomato genome and growing a new plant.

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  2. Revolutionary method to map brains at single-neuron resolution successfully demonstratedRead the original story w/Photo

    Wednesday Aug 17 | EurekAlert!

    MAPseq uses RNA sequencing to rapidly and inexpensively find the diverse destinations of thousands of neurons in a single experiment in a single animal IMAGE: An injection into a 'source' region of the brain contains a viral library encoding a diverse collection of barcode sequences, which are hitched to an engineered protein that is designed... view more Cold Spring Harbor, NY - Neuroscientists today publish in Neuron details of a revolutionary new way of mapping the brain at the resolution of individual neurons, which they have successfully demonstrated in the mouse brain.

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  3. New manual on Fission Yeast from Cold Spring Harbor Laboratory PressRead the original story w/Photo

    Wednesday Aug 17 | EurekAlert!

    IMAGE: A false-colored scanning electron micrograph of vegetative rod-shaped Schizosaccharomyces pombe cells next to the product of sexual differentiation, an ascus. view more Fission yeast are unicellular, rod-shaped fungi that divide by medial fission.

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  4. New book on Antibiotics and Antibiotic Resistance from CSHLPressRead the original story w/Photo

    Tuesday Aug 16 | EurekAlert!

    One of the greatest medical accomplishments of the past century was the introduction of antibiotics into the clinic. However, the use of these lifesaving drugs rapidly led to the emergence of antibiotic-resistant pathogens, which have become increasingly difficult and expensive to eradicate.

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  5. Novel drug therapy kills pancreatic cancer cells by reducing levels of antioxidantsRead the original story w/Photo

    Jul 27, 2016 | EurekAlert!

    Reducing levels of antioxidants in pancreatic cancer cells can help kill them, newly published research reveals, suggesting an entirely new treatment strategy for the notoriously lethal illness, in which less than 5 percent of patients survive 5 years. Although it has become almost a matter of conventional wisdom in popular culture that raising antioxidant levels in the body tends to keep cancer at bay, a team at Cold Spring Harbor Laboratory demonstrates in a series of sophisticated experiments that in the specific context of pancreatic cells on the road to cancer or already in a malignant state, the last thing one wants to do is to raise antioxidant levels.

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  6. To divide or not: a cellular feedback loop enables new cells to make a fateful decisionRead the original story w/Photo

    Jul 25, 2016 | EurekAlert!

    It is one of the wonders of nature: multiplying cells are able to precisely copy their genetic material, once and only once, and spatially segregate the resulting two sets of chromosomes when the time comes to separate into two "daughter" cells. Just in our blood system alone, we have about 500 million cells born in the bone marrow every minute of our lifetime.

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  7. The 80th CSH Symposium Proceedings addresses 21st Century Genetics: Genes at WorkRead the original story w/Photo

    Jul 18, 2016 | EurekAlert!

    IMAGE: This is the south wall of a mural depicting Detroit Industry , 1932-33 , Rivera, Diego . view more The 80th Cold Spring Harbor Symposium was held to mark the 150th anniversary of Gregor Mendel's landmark 1865 presentation of his paper "Experiments on Plant Hybridization", which laid the groundwork for modern genetics.

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  8. Discovery of new ovarian cancer signaling hub points to target for limiting metastasisRead the original story w/Photo

    Jul 9, 2016 | EurekAlert!

    Like pancreatic cancer, cancer of the ovaries is notorious for being discovered at a relatively late stage - after it has spread to other sites in the body. It is not called "the silent killer" for nothing.

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  9. An elegant way of pinpointing how new drugs exert beneficial effectsRead the original story w/Photo

    Jul 4, 2016 | EurekAlert!

    A collaborative effort by cancer researchers at Cold Spring Harbor Laboratory and chemists at Boehringer Ingelheim , a pharmaceutical firm, has resulted in the identification of a new drug target in leukemia and creation of a candidate drug that hits the target. Perhaps even more important, the research demonstrates a new, highly accurate way of proving how this and certain other classes of drugs work -- extremely valuable information in the risky business of drug development.

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  10. Gene hunters find rare inherited mutations linked to bipolar disorderRead the original story w/Photo

    Jun 26, 2016 | EurekAlert!

    Using so-called next-generation genome sequencing, researchers at Johns Hopkins have identified 84 potential inherited gene mutations that may contribute to the most severe forms of bipolar disorder. About 5.6 million Americans are estimated to have bipolar disorder.

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  11. 'Amazing protein diversity' is discovered in the maize plantRead the original story w/Photo

    Jun 23, 2016 | EurekAlert!

    The genome of the corn plant - or maize, as it's called almost everywhere except the US - "is a lot more exciting" than scientists have previously believed. So says the lead scientist in a new effort to analyze and annotate the depth of the plant's genetic resources.

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  12. Summer session fruit fly data leads to promising new target in colorectal cancerRead the original story w/Photo

    Jun 15, 2016 | EurekAlert!

    IMAGE: University of Colorado Cancer Center study shows how TIP60 and CDK8 cooperate to regulate HIF1A, allowing tumors to survive low-oxygen environments. view more In summer 2011, University of Colorado Cancer Center investigators Joaquin Espinosa, PhD, and Matthew Galbraith, PhD, taught a summer symposium on gene expression at Cold Spring Harbor Laboratory in Long Island, New York.

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  13. New stem cell pathway indicates route to much higher yields in maize, staple cropsRead the original story w/Photo

    May 15, 2016 | EurekAlert!

    Biologists at Cold Spring Harbor Laboratory have made an important discovery that helps explain how plants regulate the proliferation of their stem cells. The discovery has near-term implications for increasing the yield of maize and many other staple crops, perhaps by as much as 50%.

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  14. New book on the p53 protein from Cold Spring Harbor Laboratory PressRead the original story w/Photo

    May 4, 2016 | EurekAlert!

    Decades of research on the tumor suppressor p53 have revealed that it plays a significant role as a "guardian of the genome," protecting cells against genotoxic stress. In recent years, p53 research has begun to move into the clinic in attempts to understand how p53 is frequently inactivated in--and sometimes even promotes--human cancer.

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  15. Crossref to accept preprints in change to long-standing policyRead the original story w/Photo

    May 4, 2016 | EurekAlert!

    Crossref will enable registration for preprints by August 2016. Crossref's original registration policy prevented its members from registering content and assigning Digital Object Identifiers to "duplicative works."

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  16. Study suggests bipolar disorder has genetic links to autismRead the original story w/Photo

    May 3, 2016 | EurekAlert!

    A new study suggests there may be an overlap between rare genetic variations linked to bipolar disorder and those implicated in schizophrenia and autism. The study, by researchers at the University of Iowa Carver College of Medicine, Johns Hopkins School of Medicine, and Cold Spring Harbor Laboratory and published recently in JAMA Psychiatry , adds to the growing understanding that many psychiatric diseases share genetic roots, but is among the first to suggest a genetic overlap between bipolar disorder and autism.

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  17. Our brain uses statistics to calculate confidence, make decisionsRead the original story w/Photo

    May 3, 2016 | EurekAlert!

    The directions, which came via cell phone, were a little garbled, but as you understood them: "Turn left at the 3rd light and go straight; the restaurant will be on your right side." Ten minutes ago you made the turn.

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  18. Our brain uses statistics to calculate confidenceRead the original story w/Photo

    May 3, 2016 | EurekAlert!

    Human brains are constantly processing data to make statistical assessments that translate into the feeling we call confidence, according to a study published May 4, 2016 in Neuron . This feeling of confidence is central to decision making and, despite ample evidence of human fallibility, the subjective feeling relies on objective calculations.

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  19. First structural views of the NMDA receptor in action will aid drug developmentRead the original story w/Photo

    May 1, 2016 | EurekAlert!

    Structural biologists at Cold Spring Harbor Laboratory and Janelia Research Campus/HHMI, have obtained snapshots of the activation of an important type of brain-cell receptor. Dysfunction of the receptor has been implicated in a range of neurological illnesses, including Alzheimer's disease, Parkinson's disease, depression, seizure, schizophrenia, autism, and injuries related to stroke.

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  20. USC professor awarded $11.25M to lead brain-machine interface researchRead the original story w/Photo

    Apr 18, 2016 | EurekAlert!

    Maryam M. Shanechi, Assistant Professor & Viterbi Early Career Chair in the Ming Hsieh Department of Electrical Engineering at the USC Viterbi School of Engineering, has been awarded a Multidisciplinary University Research Initiative grant to lead an interdisciplinary team that will develop brain-machine interfaces to enhance human decision making. The award totaling $11.25 million, and provided by the U.S. Department of Defense and the UK Ministry of Defense over a five-year period, aims to connect scholars at multiple universities to take on key research challenges.

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