Touché. Those olfactory powers were spot on. (Sep 6, 2013 | post #18)
QUOTE who="Ranger88 "] Nothing you wrote explains where the building blocks come from, it only explains the theory of what is happening once they are there. [/QUOTE] Yes, that is correct, I explained what happened "once they are here", BECAUSE that is what you asked, "what about the origin of each stage of evolution?" Your exact words. Oh please, you are so disingenuous. In your first post you clearly asked how mineralization occurred. Why all of the pretense? Your first post should have said, "Where did the chemicals come from that formed the building blocks?" You never asked me that until this last disingenuous post. If you had in your first post, instead of playing games and pretending you were interested in mineralization I would have clearly said that you are speaking of abiogenesis. Did water soluble phosphorus arrive via meterorites from Mars? There is a lot of evidence that supports a yes. Do martian meteorites on earth contain boron? Definitely Yes. No one knows with certainty where or how the chemicals arrived. Does this change the fact that evolution is the reason for the diversity and complexity of life on earth today? Absolutely not. Abiogenesis =/= Evolution. (Sep 6, 2013 | post #17)
Calcium carbonate is not a proteinI showed you how the information was added. You can read about RNA world, or read about the more recent research by chemists whom are about a breath away from showing that the building blocks of DNA formed spontaneously from chemicals thought to be present on the primordial Earth or about the newly created synthetic genome that is able to self-replicate. Then you can read about how environmental stressors, chemical reactions and mechanisms are able to modify a base pair in the DNA strand to create a mutation, and this modification can lead to the creation of a new protein or enzyme. You cannot relay one or two terms of biochemistry and then genetics into one or two posts on TOPIX. (Sep 6, 2013 | post #13)
Holy Cow, Donald Prothero's review had over 2000 comments! I see that Casey Luskin also reviewed it, a glowing five stars. 8^) Anybody here read it? (Sep 5, 2013 | post #10)
Thank you SZ. (Sep 5, 2013 | post #9)
Okay, so we are going to go back further than the RUNX proteins and skeletogenesis (remember that RUNX2 deficient mice lack bone). Osteoblasts secrete ECM proteins. Hydroxyapatite crystallized on the proteins (calcium carbonate, which had been used over millions of years to build all forms of marine exoskeletons, was replaced by calcium phosphate, mostly in the form of calcium hydroxyapatite)(an d there is tons of info out there as to why). Most of the genes for the mineralizing proteins arose from a common ancestor by gene duplication to form the secretory calcium-binding phosphoprotein (SCPP) family. The SCPP family though arose from the SPARC family and SPARC was critical for initial mineralization. Research shows that SPARC and SPARCL1 initially arose by gene duplication, and subsequent tandem gene duplications generated the many SCPP genes. There are literally dozens of peer reviewed articles out there on the SCPP and SPARC families, do some researchTens of millions of years is hardly sudden, nor was it sporadic. The period of diversification during the Cambrian Period is no longer referred to as the Cambrian "Explosion " due to the misconception of "sudden" . It is now called the "Cambrian Diversification ". (Sep 5, 2013 | post #8)
Oh geez, been away too long and it appears I have been hoodwinked? I thought it was an honest question. Do you have a link by chance to this debate? What is the name of Meyer's new book? (Sep 5, 2013 | post #4)
Begin your research with how CaCO3 appeared in the environment. Then research how and why this was replaced by a phosphate based mineralization. Then look into the expression of the RUNX proteins. This will give you a good start in your research. (Sep 5, 2013 | post #2)
Celebrating kids as they head back to college. These student engineers rock: https://youtube.go ogleapis.com/v/KEB JmZL8G1E (Aug 23, 2013 | post #1098)
Hi friend, hope all is well across the pond as well! (Aug 20, 2013 | post #470)
With a screen name of "Beers" I am not surprised. :) Never hurts to try though does itNice to "see" you also Terry. 8^) (Aug 20, 2013 | post #469)
DNA is not complex. C'mon, this is not a hard concept to understand. In today's world of personalized medicine and personalized genome mapping everyone is learning and teaching themselves about the basic concepts. DNA came from RNA. Go to the DNA Learning Center that we use to explain concepts: http://www.dnalc.o rg/ Scroll down to the bottom, see the link that says "DNA from the Beginning"? Click on it. Follow along and learn the basics. Once you have learned the basics, go back to the Learning Center home page. In the search box type "How did DNA evolve?" If you have trouble reading about it, then click on any of the auditory clips and listen to the different scientists explain it to you. Ray Gesteland's clips are good. He is a Distinguished Professor of Human Genetics. His research is on RNA, specifically secondary structures in RNA that can provide additional coding information. If you want to debate biological concepts, then make an effort to teach yourself a little about the subject matter. (Aug 19, 2013 | post #429)
I can just hear that cat saying "Oh yeah just can't get enough of this winter baby" (read in Barry White type voice) that just about sums it up. Shoot, previous post should also have referenced Barry, not Lou. (Jan 10, 2013 | post #243)
Scoundrel...rub it in. We had three different storms during Christmas week. During one of them I sat on the turnpike for literally hours in the mountains. Shut the car off, popped the trunk, grabbed books and Christmas cookies and just sat there, reading, eating and watching people scurry over the hill to use the "facilities ". (Jan 10, 2013 | post #242)
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