Platelet Count News

Viewer Question: What are some of the potential diagnoses when a person has a high platelet count? Dr.

Revolade Data Presented At EHA: Updated Data For EXTEND Plus New Data For REPEAT And DELPHI Studies Main Category: Blood / Hematology Also Included In: Clinical Trials / Drug Trials ; Conferences ; Pharma ...

Amgen Inc. today announced updated results from the ongoing, open-label extension study on the long-term safety and efficacy of romiplostim in adult patients with chronic immune thrombocytopenic purpura , a ...

Abstract BACKGROUND: Vancomycin has only rarely been implicated as a cause of thrombocytopenia, and there is only limited evidence that this complication is caused by immune mechanisms.

A team led by Howard Hughes Medical Institute investigator Jamey D. Marth has shown that a prominent protein on the surface of liver cells protects organisms during sepsis, one of the most common and deadly ...

“The Ashwell receptor is 'turned on' after birth, and this was a clue that it is needed for environmental and pathogenic challenges”

London, May 19 : In a new study, researchers at the University of California, San Diego School of Medicine have found that the Ashwell receptor, a molecule present in liver of all animals, plays a key role in ... via The London News.Net

“Researchers from around the world have requested to study Abbott's Bcl-2 family protein inhibitors, which is an indication of the potential value that ABT-263 might bring to the cancer research field”

Both compounds were discovered by Abbott scientists and are being co-developed by Abbott and Genentech. via Earth Times

To the Editor: McHutchison et al. 1 report that eltrombopag raises the platelet count in patients with hepatitis C cirrhosis and thrombocytopenia. via New England Journal of Medicine

Abstract The accuracy of three automated haematology analysers [Sysmex XE-2100 , Bayer Advia 120, and Beckman Coulter LH-750] was compared with the immunoplatelet reference method for platelet measurement. via CiteULike

Abstract BACKGROUND: The pathogenesis of chronic idiopathic thrombocytopenic purpura involves antibody-mediated platelet destruction and reduced platelet production. via CiteULike

Abstract BACKGROUND: Chronic immune thrombocytopenic purpura is characterised by accelerated platelet destruction and decreased platelet production. via CiteULike

“We also have an additional clinical trial, now open to enrollment, evaluating a low-dose, subcutaneous formulation of veltuzumab in patients with non-Hodgkin's lymphoma or chronic lymphocytic leukemia”

Immunomedics, Inc. , a biopharmaceutical company focused on developing monoclonal antibodies to treat cancer and other serious diseases, today announced that patient dosing has begun in a Phase I/II clinical ... via Med Ad News

“Adult ITP is a serious chronic autoimmune disorder characterized by low platelet counts in the blood, a condition known as thrombocytopenia”

Main Category: Infectious Diseases / Bacteria / Viruses Also Included In: Clinical Trials / Drug Trials Article Date: 04 Feb 2008 Amgen Inc. via MediLexicon

Certain of these patients may be refractory to steroids, intravenous anti-D, intravenous immunoglobulin , and splenectomy. via CiteULike

Association of insulin resistance and hematologic parameters: study of a middle-aged and elderly Chinese population in Taiwan. via CiteULike

“In this study, eltrombopag increased platelet counts in a dose-dependent manner, allowing more patients to complete the first 12 weeks of antiviral therapy--an important treatment goal”

This problem is compounded by the fact that standard antiviral treatment for the disease can further reduce platelet numbers to dangerously low levels, effectively denying these patients the treatment they ... via Science Daily

A report in the New England Journal of Medicine says the drug eltrombopag appears to significantly boost platelet counts in hepatitis C patients. via The Post Chronicle

“In this study, eltrombopag increased platelet counts in a dose-dependent manner, allowing more patients to complete the first 12 weeks of antiviral therapy -- an important treatment goal”

For patients with hepatitis C, having a low blood platelet count is a frequent complication associated with advanced disease. via EurekAlert!

The threshold for prophylactic platelet transfusions in adults with acute myeloid leukemia. via CiteULike

“GSK is pleased with the data provided to support the NDA and hopeful that, if approved, PROMACTA may provide physicians and chronic ITP patients with a new, convenient and effective option for treating this difficult disease.”

GlaxoSmithKline Files For FDA Approval Of PROMACTA To Be The First Oral Platelet Growth Factor For Rare Blood Disorder Main Category: Blood / Hematology Also Included In: Pharma Industry / Biotech Industry ... via MediLexicon