margeRobert the above was from Mark 6, and here again in Matt 13 He says the same;
And they took offense at him. But Jesus said to them, "Only in his hometown and in his own house is a prophet without honor."
And here His family says;
When his family heard about this, they went to take charge of him, for they said, "He is out of his mind."
Mark 3 21 is definitely a hard verse.
One begins by thinking, "How can Jesus be out of his mind, because He is God? That would be like saying God is out of His Mind?"
But upon thinking about it. There are two answers that come to my mind. This first is that God's Mind is beyond our understanding. And what he is doing is beyond what his family and kin can understand.
Secondly, the concern for the safety of Jesus by his kin and family, as well as his health are the cause of such an outburst.
We can see something of this concern by Peter toward Jesus, on two occasions. The first is when he doesn't want Jesus to die, and the subsequent saying of Jesus for Satan to get behind..., and the second is when he cut off Malchus ear in the Garden when protecting Jesus....
I think we all have that "instinct" to protect Jesus. But it is best to let him lead, and we follow. He knows so much more....