No evidence of "Chemical Imbalance" F...

No evidence of "Chemical Imbalance" FDA says......

Posted in the Top Stories Forum

Leonard Pratt III

United States

#1 Apr 2, 2006
Promoting Openness, Full Disclosure, and Accountability


"Biological psychiatrists have looked very closely for a serotonin imbalance or dysfunction in patients with depression or obsessive compulsive disorder and, to date, it has been elusive," says Dr. Wayne Goodman, Chair of the US Food and Drug Administration (FDA) Psychopharmacologic Drugs Advisory Committee.

Psychiatry's drug prescribing practices rest on a myth debunked by Jeffrey Lacasse and Jonathan Leo in their article in PLoS Medicine. Not a single representative of mainstream psychiatry has come forward to rebut them.

Lacasse and Leo lay out the case against psychiatry's bedrock justification for prescribing psychotropic drugs. For decades psychiatry's leadership and chorus of followers have claimed that depression is caused by a "chemical imbalance" in the brain, and that SSRI antidepressants normalize that "chemical imbalance."

But such claims have been overturned In the absence of evidence. As Lacasse and Leo have shown, not a single peer reviewed article validates the theory of a chemical or biological marker abnormality in persons diagnosed with depression--or, for that matter with any psychiatric disorder.

Thus, neurologist, Dr. Frederick Baughman argues, in the absence of a confirmed disease, no medical intervention is justified.

Evidence does exist showing that the drugs have serious adverse effects which, for some individuals, cause permanent damage.

Furthermore, some of the prescribed drugs are controlled class II substances--which means they are highly addictive!

We are led to ask: What is the justification for giving psychiatrists a license to prescribe psychotropic drugs in the absence of evidence that:

1. A pathological abnormality is present;
2. The prescribed intervention (drug) is proven safe;
3. The intervention is proven effective to treat the pathology;
4. The benefit / risk ratio is favorable for those for whom it is prescribed.

See: Jeffrey R. Lacasse, Jonathan Leo. Serotonin and Depression: A Disconnect between the Advertisements and the Scientific Literature, PLoS Medicine, Dec 2005 at: ...

See also:

Contact: Vera Hassner Sharav
[email protected]

I honeslty believe that the industry itself is in dire need of an enema. I hope that this report get things rolling.



United States

#2 Apr 3, 2006
Jeez, no replies to this? I am surprised but then I'm not surprised. I suppose the truth is not interesting enough for most people or that it's more intesresting to have a mystery sandwich on your plate and keep it unsolved. Let's not cofront the reality, that always works. One reason this nation is in such trouble.
Anyway, it's gross to me what's going on.


Troy, MI

#3 Apr 25, 2006
This is interesting. You always hear "Chemical Imbalance" used almost as freely as "Got Milk?" I read something back a while about a neurologist in San Diego or therabout that really turned the screws on this "theory" and basically got a big top hat and cane show from the NIMH and CHADD. It was funny that he backed them into a corner and to this day is not challenged on his point of lack of proof of abnormality.
His name is Dr. Fred Baughman. I googled him when I got an e-mail from a friend. Great stuff.


Leonard Pratt III

Troy, MI

#4 Apr 25, 2006
I've read his bibliography. It's amazing.
Just google Dr. Fred Baughman and click on his testimony. This guy is for real.


Tell me when this thread is updated:

Subscribe Now Add to my Tracker

Add your comments below

Characters left: 4000

Please note by submitting this form you acknowledge that you have read the Terms of Service and the comment you are posting is in compliance with such terms. Be polite. Inappropriate posts may be removed by the moderator. Send us your feedback.

Top Stories Discussions

Title Updated Last By Comments
The Christian Atheist debate (Jun '15) 3 min VIKING 48,117
White women leaving their white families in dro... (Aug '09) 5 min Johnny 328
Prove there's a god. (Mar '08) 22 min VIKING 971,584
News Roman Catholic church only true church, says Va... (Jul '07) 35 min Phooey 646,369
Poll Is homosexuality a sin? (Oct '07) 47 min Puppet master 105,553
Why Should Jesus Love Me? (Feb '08) 48 min Just Wondering 618,557
Bush is a hero (Sep '07) 1 hr Yellow Star 182,623
More from around the web