cyd pamam
Anonymous

Weihai, China

#1 Apr 18, 2013
The newly constructed dendrimer hydrogels possess high structural flexibility, high water absorptivity, good cytocompatibility, and controlled swelling and disintegration through the modulation of dendrimer surface charges and modification. PAMAM dendrimer (CY Dendrimer Technology Co., Ltd)hydrogels uniquely express the structural characteristics of both PEG hydrogel and PAMAM dendrimer and have potential for various applications in tissue engineering and drug delivery.
The hydrogel has the following advantages and application prospects:(1). They allow simultaneous delivery of both hydrophobic and hydrophilic drugs . In particular, the interior hydrophobic core of the dendrimer would encapsulate hydrophobic compounds, thus, increasing their water solubility and loading amounts, while the cross-linked PEG network enables the encapsulation of hydrophilic drugs.(2). The surface charges conferred by terminal groups on the dendrimer surface can be modulated to make the hydrogel polyionic with controllable charge density.(3). Their unique spatial structure and configuration with high adaptability may present themselves a suitable platform for fine-tuning of cell-scaffold interactions in tissue engineering.
(Synthesis and Characterization of Photocurable Polyamidoamine Dendrimer Hydrogels as a Versatile Platform for Tissue Engineering and Drug Delivery, Pooja N. Desai, American, Biomacromolecules, Vol. 11, No. 3, 2010, 667)

Tell me when this thread is updated:

Subscribe Now Add to my Tracker

Add your comments below

Characters left: 4000

Please note by submitting this form you acknowledge that you have read the Terms of Service and the comment you are posting is in compliance with such terms. Be polite. Inappropriate posts may be removed by the moderator. Send us your feedback.

Top Stories Discussions

Title Updated Last By Comments
The Christian Atheist debate 1 min Critical Eye 4,134
Prove there's a god. (Mar '08) 3 min Cherokee Prince 881,530
Poll If you're Christain what kind are you? (Oct '07) 4 min princeofdarknessi... 8,394
News Roman Catholic church only true church, says Va... (Jul '07) 9 min phooey 603,755
gay bottom in gurgaon (May '14) 23 min sisank 587
I need an urgent loan in the next hour (Oct '13) 50 min tracy 15
You want REAL PROOF that God is REAL??! 1 hr Doctor REALITY 9
Which is the Oldest Indian Language? Sanskrit V... (Jul '08) 1 hr sangili karuppan 7,700
More from around the web