Question concerning absorption

Question concerning absorption

Posted in the Pharmacology Forum

Since: Oct 12

Lexington, NC

#1 Oct 19, 2012
Hi. First off I am not a medical professional nor am I skilled beyond basic college in Science. Any help with my questions would be greatly appreciated.
THere is a growing number of people moving from cigarettes to ecigs. I have been doing some research on how they work. Now the crave seems to be diy mixing. I do know that the accepted amount of nicotine to kill a human is lcd 50mg per 70kg of weight. I get that. Here is what i dont get. A lot of people on the forums are saying they spill this large concentrate liquid on themselves and never feel any adverse effects.
Lets say i'm using a common mix of 100mg/ml or 100mgs of nicotine per mil of liquid. The nicotine is diluted in either VG PG or a combination of the 2. If someone were to truely spill 1 ml of this liquid on thier skin would they not absorb 100mgs of nicotine thereby causing death?
Is there a way to determine the rate human skin would absorb the nicotine to the bloodstream? Would the VG, PG, or combination make the absorption faster? slower? no change?
What about consistent exposure to nonsmokers/nicotine users. Would there be a potential of addiction with prolonged exposure to this?

Tell me when this thread is updated:

Subscribe Now Add to my Tracker

Add your comments below

Characters left: 4000

Please note by submitting this form you acknowledge that you have read the Terms of Service and the comment you are posting is in compliance with such terms. Be polite. Inappropriate posts may be removed by the moderator. Send us your feedback.

Pharmacology Discussions

Title Updated Last By Comments
News Where to buy dichloroacetate... (Jul '07) May '17 Judydowellb 51
5ht2b antagonist (Jan '17) Jan '17 aransheehan 1
Pharmacology Review Quiz is now from paid to free? (Nov '16) Nov '16 CollinHarrams 1
FDA: Adverse Reactions Website (May '08) Aug '16 jrdrmotwani 2
On binding plasma proteins... (Apr '15) Aug '16 jrdrmotwani 2
Dose-dependent or not (Mar '16) Mar '16 sam 1
News Could Music Be the Next Great Cure? (Apr '09) Aug '15 Tijesuni 8
More from around the web