Chromosome 10 inversion

Chromosome 10 inversion

Posted in the Genetics Forum


Round Lake, IL

#1 Apr 10, 2006
Does anyone know anything about being a "carrier" of inverted chromosome 10? Are there any case studies about this?

Great Bend, KS

#2 Jul 18, 2006
Emilee wrote:
Does anyone know anything about being a "carrier" of inverted chromosome 10? Are there any case studies about this?
My ex-boyfriend carried the gene which was responsible for an inverted Chromosome 10


#3 Jan 24, 2007
Emilee wrote:
Does anyone know anything about being a "carrier" of inverted chromosome 10? Are there any case studies about this?
My daughter, as her father, also are carriers of an "inverted chromosome 10". If you have since found any information I would appreciate it if you could pass it on to me.

San Diego, CA

#4 May 10, 2007
Invented chromosome 10 can relate to reproductive anomalies A normal XX female with an inversion 10 may lack a uterus or have another abnormality of a reproductive nature. Menses may be absent as the first sign if the inversion wasn't previously discovered. Growth problems can occur, but unless other factors interfere, intelligence is not affected. Hopefully, geneticists will provide us with more info and perhaps treatment. Also, let us know if these 'carriers' are familial or recessive or what? With billions of miles of chromosome strands in each cell, it is amazing to me that any info is available. More funding is needed; our government lags.
Germaine waubay sd

Hayti, SD

#5 Mar 14, 2008
My son is only 2 1/2 yrs old he has a flipped chromozone 10 he has a lot of problems he can barely say 5 words if im lucky he has sleep apnea.Theres alot of problems and it wasnt passed from me or his father so we don't know what happen you can contact me at [email protected]

Flushing, NY

#6 May 6, 2009
Emilee wrote:
Does anyone know anything about being a "carrier" of inverted chromosome 10? Are there any case studies about this?
I am a carrier of a chromosome 10 inversion and all they could tell me is that is may have causes of more miscarriages.

United States

#8 Jan 7, 2010
I have the 10th inversion and i am fine---my 6yr old son inherited it from me and he has been diagnosed with autism
Stephany McDowell


Since: Apr 08

Location hidden

#9 Jan 8, 2010
The cure for chromosome ten inversion is reciprocity.

Cheraga, Algeria

#10 Apr 1, 2010
I understand that cromosome 10 inversion is a problem only if you have lost of materia (so information).
But how come that a normal person trasmit the abnormal cromosm to a son and only the son has issue?
Can be that the son get initially the good cromosome and he get an inversion with lost of material only during this conception?
Did you guy ever did a FISH to confirm no lost of material?

United States

#11 Sep 3, 2011
Yes, my son's father was tested and there was no missing material---his chromosomes are fine.
I'm not sure if the inversion has anything to do with my son's autism---most MD's say no---one says it is possible.

United States

#12 Sep 3, 2011
My son's father was tested and there is no missing material---he has normal chromosomes.
Most MD's say the inversion has nothing to do with his autism--One MD has said it's possible that the inversion has something to do with it.
Hulya Istanbul

Istanbul, Turkey

#13 Nov 3, 2011
I am 46 years old . Myself and my 12 years old doughter , we both have inverted chromosome 10 (no loss,nor deletion). I have endometriosis, and had difficulties with fertilization but otherwise we both are in good health so far. Hope we will stay as we are. Next week my 73 yo mother will also have genetic testing. I will let you all now is she has the same invertion.

Negaunee, MI

#14 Feb 17, 2012
i made a mistake it was passed by his father

Marietta, GA

#15 Feb 17, 2012
I have an inverted as does my 14 yo daughter. I had the amnio when I was pregnant with her. They then did blood test of her father & I. They said if one of us were inverted #10 then all is well b/c we are normal.

I had easy pregnancies & got pregnant very easily. My daughter has ADHD, but other than that is extremely intelligent and a compete joy.

I think inverted #10 means nothing.

Livingston, NJ

#16 Mar 9, 2012
I am 57 and have an inverted 10. I have not had and problems.
My son is 20 and so far everything is good with him. It was discovered
in my son before he was born. That is when i got tested and found that I too had it. Until it was found out that i had the inversion, the doctor was concerned
and wanted us to go to counseling.

Georgetown, TX

#17 Mar 25, 2012
I hope my post is helpful. I had 3 miscarriages, each one around 14 to 16 weeks. After the 3rd miscarriage, the fetus was tested and no genetic abnormalities found. My fertility OB specialist thought my miscarriages were therefore a random thing. I then became pregnant with my 4th pregnancy and final pregnancy. At 16 weeks, I had an amniocentisis which revealed that the fetus carried an inverted 10 chromosome. Full genetic testing was done on my husband and I. It revealed that my husband was the carrier for the inverted number 10 chromosome. I delivered a healthy baby girl. She is now twenty, and of superior intelligence. However, she was diagnosed in her early teens with hypothryoidism and about a month ago with bipolar disorder. Those two diseases are related and an inverted 10 can be responsible. The inverted 10 also caused my fertility issues and the miscarriages. Through extensive geneology research, we have discovered there many others on my husband's side that also have those two diseases.

Beringen, Belgium

#18 Aug 9, 2013
I'm Also carier of inversie 10. I never had problems until i want to have children. It take 2 years to get pregnant . And let me testet, my sun was Also carier. Now he is 4 years old and nothing is wrong whit him. And my little girl 2 years old has no inversie.

I'm happy to see we are not alone. In belgium there arent Many people whit The same inversie.

Istanbul, Turkey

#20 Sep 22, 2015
Hi I am Hulya.I am 50 years old Now. Me and my 15 years old daughter have 10th chromosome inversion. We recently have my father tested and he also has 10th chromosome inversion. He is 77 years old. He has a coronary stenting for ischemic heart disease last year. Other then this he is very healthy and energetic. So I think he is the proof of inversion of 10th chromosome does not causes a serious problem. I hope this will be helpful to others.

Midlothian, VA

#21 Monday May 1
I have an inversion on chromosome 10. My dad has it, my sister has it, and my son has it. It hasn't caused any problems for us. My sister has NF but its unrelated. I don't have any major physical problems. I am bipolar but I also have a Masters degree in Chemistry. So take what you want out of that.

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