Race may play role in presentation of triple-negative breast cancer in hispanic women

Apr 3, 2012 | Posted by: roboblogger | Full story: EurekAlert!

Hispanic women in Puerto Rico who have triple-negative breast cancer share similar disease characteristics with Hispanic women in California, suggesting that race plays a significant role in the presentation of triple-negative breast cancer among Hispanic women.

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to make dave happy

San Juan, Puerto Rico

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#1
Apr 4, 2012
 

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For god sakes hispanic is not a race!!!!!!!!!!
TPMP

Bronx, NY

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#2
Apr 5, 2012
 
This could open up a whole new field of research.

Intresting.

Our descendants are from Spain. Many from both nationalities have Amerindian blood. It makes sense.

I see the correlation.
to make dave happy

San Juan, Puerto Rico

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#3
Apr 5, 2012
 

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TPMP wrote:
This could open up a whole new field of research.
Intresting.
Our descendants are from Spain. Many from both nationalities have Amerindian blood. It makes sense.
I see the correlation.
here we go again.
Gail Perry

Saint Petersburg, FL

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#4
Apr 5, 2012
 
to make dave happy wrote:
<quoted text>
here we go again.
I hope researchers won't let political corretness get in the way of research again.

Years ago, researchers spotted an inordinate number of women with breast cancer living on Long Island. They looked and looked and looked for an environmental cause, ignoring the high number of Jewish women living there.

Turned out that one subset of Jewish people are highly likely to carry the BRCA-1 or -2 gene. By looking at ethnic issues they discovered really important information. Those genes are not limited to Jewish women, and they aren't the only genes involved in breast cancer.

It's not exposure to Spanish that causes breast cancer any more than it's exposure to Yiddish. But by noticing this pattern, they may find genes. Finding the genes could eventually lead to improved treatment for triple-negative breast cancer, a form that is challenging to treat.

If *I* had a family tree that included Hispanics (in fact my daughters DO)-- I would want it researched right away. I don't think I'd be wringing my hands because someone uttered the "H" word. it's not a slur. It's something to be proud of. It may be medically significant as well, however.
TPMP

Bronx, NY

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#5
Apr 5, 2012
 
to make dave happy wrote:
<quoted text>
here we go again.
Here we go again, what?. This is NOT about race.

It is about breast cancer and the possible links between diffrent ethnic groups who both happen to fall under the Hispnic umbrella.

You have a mighty omplex with this race buisness.

Give it a break!!

Get a shrink.
TPMP

Bronx, NY

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#6
Apr 5, 2012
 
Gail Perry wrote:
<quoted text>
I hope researchers won't let political corretness get in the way of research again.
Years ago, researchers spotted an inordinate number of women with breast cancer living on Long Island. They looked and looked and looked for an environmental cause, ignoring the high number of Jewish women living there.
Turned out that one subset of Jewish people are highly likely to carry the BRCA-1 or -2 gene. By looking at ethnic issues they discovered really important information. Those genes are not limited to Jewish women, and they aren't the only genes involved in breast cancer.
It's not exposure to Spanish that causes breast cancer any more than it's exposure to Yiddish. But by noticing this pattern, they may find genes. Finding the genes could eventually lead to improved treatment for triple-negative breast cancer, a form that is challenging to treat.
If *I* had a family tree that included Hispanics (in fact my daughters DO)-- I would want it researched right away. I don't think I'd be wringing my hands because someone uttered the "H" word. it's not a slur. It's something to be proud of. It may be medically significant as well, however.
Excellent post.
TPMP

Bronx, NY

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#7
Apr 5, 2012
 
Correction:complex
Gail Perry

Saint Petersburg, FL

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#8
Apr 5, 2012
 
Thank you, TPMP! This is tame compared to the threads talking about the unusually high occurrence of triple-negative cancer among Black women.

Personally I think Black women need to know that. It's EXTREMELY important to catch triple-negative as soon as possible. And, we need research to pinpoint the reasons, because it appears that even when a research group is controlled for income, access to health insurance, access to good medical centers, and regular medical checkups, the incidence is STILL higher than it is for the general population.

Once again, we need to know why, not whine and wring our hands any time race is mentioned. Black women of the world deserve better than such childish temper tantrums.

Other than that I have no opinion (smile).
to make dave happy

San Juan, Puerto Rico

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#9
Apr 7, 2012
 
TPMP wrote:
<quoted text> Here we go again, what?. This is NOT about race.
It is about breast cancer and the possible links between diffrent ethnic groups who both happen to fall under the Hispnic umbrella.
You have a mighty omplex with this race buisness.
Give it a break!!
Get a shrink.
I will suggest for you to review your post again. You are the one with the complex, you made your own interpretation, so who's the one who need a shrink. I am a puertorican (born and raised in the island, and still live here) and I clearly know where we come from.
to make dave happy

San Juan, Puerto Rico

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#10
Apr 7, 2012
 
Gail Perry wrote:
Thank you, TPMP! This is tame compared to the threads talking about the unusually high occurrence of triple-negative cancer among Black women.
Personally I think Black women need to know that. It's EXTREMELY important to catch triple-negative as soon as possible. And, we need research to pinpoint the reasons, because it appears that even when a research group is controlled for income, access to health insurance, access to good medical centers, and regular medical checkups, the incidence is STILL higher than it is for the general population.
Once again, we need to know why, not whine and wring our hands any time race is mentioned. Black women of the world deserve better than such childish temper tantrums.
Other than that I have no opinion (smile).
So what are your opinions for those women who are hispanic descendant and have black skin. The reason why I said here we go again is because there is some kind of sterotype about hispanic women looking in a certain way, when we all know that such sterotype is not true, right THIS IS NOT A RACE ISSUE, but in order to make such an observation is very important to know that as hispanic the indian and african blood is present, they are part of our ancestors too, if that point upset or offends someone then they than individual need some soul searching.
to make dave happy

San Juan, Puerto Rico

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#11
Apr 7, 2012
 
As a matter of fact there is report about asma in PR children, and one of the observation of the researches is that you can genelarized in our group, since we are all racially mixed. Is it a race issue??? NO. Is just a point of view,but if mentioning that we are not white upsets you, or makes you feel uncomfortable, once again, soul searching. It is so easy to talk we you are looking from far..... huhhhhhhhhhhhhh
to make dave happy

San Juan, Puerto Rico

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#12
Apr 7, 2012
 
Believe me is there is an island fighting hard against cancer and embracing the cure is Puerto Rico. Dont you know about all the journalists who have fought and embrace the cause, all the coalitions, and investigation, how we have contribute to save Hospital Oncologico??? Of course you dont know you are not here, people like you makes me so upset. So proud puertoricans my ass...
to make dave happy

San Juan, Puerto Rico

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#13
Apr 7, 2012
 
AND ONCE AGAIN HISPANIC IS NOT A RACEEEEE!!!!
Es un origen por Dios!!!
Gail Perry

Oldsmar, FL

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#14
Apr 8, 2012
 
to make dave happy wrote:
<quoted text>
So what are your opinions for those women who are hispanic descendant and have black skin. The reason why I said here we go again is because there is some kind of sterotype about hispanic women looking in a certain way, when we all know that such sterotype is not true, right THIS IS NOT A RACE ISSUE, but in order to make such an observation is very important to know that as hispanic the indian and african blood is present, they are part of our ancestors too, if that point upset or offends someone then they than individual need some soul searching.
@@

This isn't about APPEARANCES. Anyone who has had any contact with New World Hispanic societies know that appearance varies. I suggest that you read up on research methodology. You are the only one talking about anyone being offended.

ONE way to deal with the issue of mixed ethnic heritage (it is true in ALL populations, by the way, not just Hispanic)is to select for people who are largely from one or another genetic body. My daughters would be a poor choice for such research: they have French, Scots, Irish, German, Spanish and English ancestors. I've probably left a few out.

One POSSIBLE way to deal with the so-called "Hispanic" pattern would be to break a group of people thus labled into groups according to their genetic ancestry. This is what they had to do with the Long Island situation I talked about. The BRCA 1 and 2 genes aren't more common in ALL Jewish populations, just one subset.

Believe me, if they could do it on Long Island they can do it again somewhere else.

You're not a researcher so I'm not going to worry about it, and the researchers are WELL aware of the patterns found because of Long Island. They know how to do it. It needs to be done.

Once they identify a gene or genes, THEN women at risk for carrying that gene cen be tested, just as women can be tested for the BRCA genes. It will have absolutely nothing to do with, say, facial features, and everything to do with individuals' DNA.
TPMP

Bronx, NY

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#16
Apr 9, 2012
 
Gail Perry wrote:
<quoted text>
@@
This isn't about APPEARANCES. Anyone who has had any contact with New World Hispanic societies know that appearance varies. I suggest that you read up on research methodology. You are the only one talking about anyone being offended.
ONE way to deal with the issue of mixed ethnic heritage (it is true in ALL populations, by the way, not just Hispanic)is to select for people who are largely from one or another genetic body. My daughters would be a poor choice for such research: they have French, Scots, Irish, German, Spanish and English ancestors. I've probably left a few out.
One POSSIBLE way to deal with the so-called "Hispanic" pattern would be to break a group of people thus labled into groups according to their genetic ancestry. This is what they had to do with the Long Island situation I talked about. The BRCA 1 and 2 genes aren't more common in ALL Jewish populations, just one subset.
Believe me, if they could do it on Long Island they can do it again somewhere else.
You're not a researcher so I'm not going to worry about it, and the researchers are WELL aware of the patterns found because of Long Island. They know how to do it. It needs to be done.
Once they identify a gene or genes, THEN women at risk for carrying that gene cen be tested, just as women can be tested for the BRCA genes. It will have absolutely nothing to do with, say, facial features, and everything to do with individuals' DNA.
What a diplomatic response. Classy. We rarely pay her much mind. Suit yourself on that one.

==========

I grew up on Long Island. We had some clusters of Cancer in Dix Hills, Commack and several other adjacent coomunities. It was an epidemic.
Gail Perry

Oldsmar, FL

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#18
Apr 9, 2012
 

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TPMP wrote:
<quoted text> What a diplomatic response. Classy. We rarely pay her much mind. Suit yourself on that one.
==========
I grew up on Long Island. We had some clusters of Cancer in Dix Hills, Commack and several other adjacent coomunities. It was an epidemic.
"Diplomatic?" It was blunt and to the point. You had clusters of cancer and YOU choose to call it an "epidemic." Clearly you know nothing about research (that was not diplomatic). People of like kind tend to cluster together. When they do this of their own choice, that's not racial, it's just human nature. That can result in concentrations of genes in specific areas. With luck and diligent research, sometimes those genes can be identified.

That's what happened with the Long Island Jewish women who turned out to have the BRCA genes. Finding those genes was delayed because of an assumption that it was an "epidemic," meaning an external cause.

There are other cases where there were concentrations of Jewish people for far uglier reasons. There was a large Jewish population for decades in south Miami Beach -- because they were blocked from buying property except in certain areas.

A familial pattern showing that bipolar disorder is up to 80% inheritable came by studying two populations -- Amish in Pennsylvania and citizens of Iceland. Neither group has any racial overtones, but due to circumstances, each group tended to have more homogeneous gene pools than typical. There's nothing in Amish life that tends to cause bipolar disorder, nor is there in Iceland. Genes are the explanation. It has since been confirmed widely in families from more heterogeneous populations.

Genes is where to look, not superficial characteristics.

I have no idea who you were insulting when you said "we rarely pay her much mind," but ... maybe you should.
TPMP

Bronx, NY

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#19
Apr 9, 2012
 
Gail Perry wrote:
<quoted text>
"Diplomatic?" It was blunt and to the point. You had clusters of cancer and YOU choose to call it an "epidemic." Clearly you know nothing about research (that was not diplomatic). People of like kind tend to cluster together. When they do this of their own choice, that's not racial, it's just human nature. That can result in concentrations of genes in specific areas. With luck and diligent research, sometimes those genes can be identified.
That's what happened with the Long Island Jewish women who turned out to have the BRCA genes. Finding those genes was delayed because of an assumption that it was an "epidemic," meaning an external cause.
There are other cases where there were concentrations of Jewish people for far uglier reasons. There was a large Jewish population for decades in south Miami Beach -- because they were blocked from buying property except in certain areas.
A familial pattern showing that bipolar disorder is up to 80% inheritable came by studying two populations -- Amish in Pennsylvania and citizens of Iceland. Neither group has any racial overtones, but due to circumstances, each group tended to have more homogeneous gene pools than typical. There's nothing in Amish life that tends to cause bipolar disorder, nor is there in Iceland. Genes are the explanation. It has since been confirmed widely in families from more heterogeneous populations.
Genes is where to look, not superficial characteristics.
I have no idea who you were insulting when you said "we rarely pay her much mind," but ... maybe you should.
(Gail Perry quoted)

"but ... maybe you should"

(unquote)


Whtever, lady!.

You are new to this forum and you are not aware of the dynamics here.

She knows what i was refering to...So don't be so quick to judge.

Perhaps this thread is posting somewhere else besides the PR forum.

==========

In any case.

You are obviouly a passionate advocate for Brest cancer research. I salute you in your efforts if you are genuine. It is a plague that must be erdicated as all cancer should be.
TPMP

Bronx, NY

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#20
Apr 9, 2012
 
Correction: obviously
to make dave happy

San Juan, Puerto Rico

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#21
Apr 9, 2012
 
Gail Perry wrote:
<quoted text>
@@
This isn't about APPEARANCES. Anyone who has had any contact with New World Hispanic societies know that appearance varies. I suggest that you read up on research methodology. You are the only one talking about anyone being offended.
ONE way to deal with the issue of mixed ethnic heritage (it is true in ALL populations, by the way, not just Hispanic)is to select for people who are largely from one or another genetic body. My daughters would be a poor choice for such research: they have French, Scots, Irish, German, Spanish and English ancestors. I've probably left a few out.
One POSSIBLE way to deal with the so-called "Hispanic" pattern would be to break a group of people thus labled into groups according to their genetic ancestry. This is what they had to do with the Long Island situation I talked about. The BRCA 1 and 2 genes aren't more common in ALL Jewish populations, just one subset.
Believe me, if they could do it on Long Island they can do it again somewhere else.
You're not a researcher so I'm not going to worry about it, and the researchers are WELL aware of the patterns found because of Long Island. They know how to do it. It needs to be done.
Once they identify a gene or genes, THEN women at risk for carrying that gene cen be tested, just as women can be tested for the BRCA genes. It will have absolutely nothing to do with, say, facial features, and everything to do with individuals' DNA.
Thank you gail. Very intelligent post.
to make dave happy

San Juan, Puerto Rico

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#22
Apr 9, 2012
 
TPMP wrote:
<quoted text> (Gail Perry quoted)
"but ... maybe you should"
(unquote)
Whtever, lady!.
You are new to this forum and you are not aware of the dynamics here.
She knows what i was refering to...So don't be so quick to judge.
Perhaps this thread is posting somewhere else besides the PR forum.
==========
In any case.
You are obviouly a passionate advocate for Brest cancer research. I salute you in your efforts if you are genuine. It is a plague that must be erdicated as all cancer should be.
El trajo un punto muy claro e inteligente. Muy diferente a tu estilo. deal with it!!

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