Week 12 NFL Picks: San Francisco 49ers and Teams on Upset Alert

The San Francisco 49ers will ride a wave of momentum into their NFC clash with the New Orleans Saints in Week 12, after their 32-7 dismantling of the Chicago Bears in prime time.

[Abby]

49ers should keep Smith in as the starting quarterback as much as possible for this season. To change it up now would be devastating to the team and will once again start that carousel (the last few years with the coaches, this time with the players) that clearly did the team no favors during the past few seasons. I'm team Smith all the way.

[geoff helms]

The 9ers run game will get a real test against the saints,maybe well see a new kind of offense for the 9ers this week?? I'm with smith too if he works out more and builds back up, he's losing weight and seems pale?

[jeffry helms]

the 2012 9er defense can be compared to the "purple people eaters", or the "steel curtain" or the raider defense in 76',