Scientists hail 'potential cure for AIDS'

Jan 17, 2013 | Posted by: Rick in Kansas | Full story: www.abc.net.au

Scientists from the Queensland Institute of Medical Research say they have made a breakthrough that could lead to a potential cure for AIDS.

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“I Am No One Else”

Since: Apr 12

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#38
Jan 17, 2013
 

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Josh in New Orleans wrote:
I wonder how it works... gene therapy? A modified HIV virus? An agent that modifies the protein or the viral DNA? Even if it is an effective cure for the disease trajectory, stuff like this usually does not pan out because of the challenges with mass production of synthetic proteins and gene therapies, and limits on the effectiveness of the delivery mechanism. The human body is more complex than what's in a petri-dish.
You forgot a successful blocker. Something that has only recently been explored, using other viruses to cause the body to switch off the chemical receptors of a virus that cannot be cured with a vaccine. Switch off the specific receptors without harming the patient, and the virus starves.

Also, the human body isn't really that much more complicated than a petri dish.

“Live and let live”

Since: Apr 08

New Orleans

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#42
Jan 17, 2013
 

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KittenKoder wrote:
<quoted text>
You forgot a successful blocker. Something that has only recently been explored, using other viruses to cause the body to switch off the chemical receptors of a virus that cannot be cured with a vaccine. Switch off the specific receptors without harming the patient, and the virus starves.
Also, the human body isn't really that much more complicated than a petri dish.
Researchers have been doing that for awhile- using a viral shell to deliver gene therapies to cells. Modifying the expression of a virus is only feasible inside a cell during viral replication. Therefore, I am skeptical because it might only work if it gets by the body's immune response, and that begs the ethical question whether turning HIV into a benign symbiote to fight its evil twin might yield a more insidious strain than the original. Retroviruses mutate constantly.

Since: May 12

Bellevue, WA

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#43
Jan 17, 2013
 

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Josh in New Orleans wrote:
<quoted text>
Researchers have been doing that for awhile- using a viral shell to deliver gene therapies to cells. Modifying the expression of a virus is only feasible inside a cell during viral replication. Therefore, I am skeptical because it might only work if it gets by the body's immune response, and that begs the ethical question whether turning HIV into a benign symbiote to fight its evil twin might yield a more insidious strain than the original. Retroviruses mutate constantly.
Josh they would use a vector like Ad-5 to carry the genes for the protein, not HIV

Since: Mar 07

The entire US of A

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#44
Jan 18, 2013
 

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The American Holocaust wrote:
Nothing conservative about queerty, abortion, taxes, or gun control and you insulting a proud father suggesting I would go and do what you suggested shows how useless of a subversive decadent box you really are.
Buh Bye.
Silly stuff.

If by "qweerty" you mean gay tax payers, then you are wrong. What true conservative wants the government involved in a citizen's personal life and marriage? Only a hypocrite would welcome such intrusion ONLY in the lives of others, while fighting ANY such intrusion in there own life.

Conservatives rely on and spend tax dollars every day. We are defended by a military that requires taxes, we drive on roads paid for by taxes. Our kids go to schools paid for by taxes.

The majority of the population, while not approving of abortion, also do not support a government requirement that ALL women be forced to carry all unwanted pregnancies to term. And a great many of those folks with those views are religious conservatives.

As a conservative, you can't require a million unwanted pregnancies that result in a million new government dependents relying on state and federal entitlements, can you? Seems a little hypocritical.

I think it's the whole "government taking control of our lives" thing. People get a little queasy about that.

Gun control is a freedom issue that every conservative should understand. YOU might feel you have a need for 10 assault weapons and endless rounds of ammunition. Many other citizens feel they have a right not to die in a hail of gunfire. It's about ALL of our freedoms, just not the freedom to carry any sort of weapon by a few irrational folks.
Just poppin in for a bit

Santa Cruz, CA

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#45
Jan 18, 2013
 
The Worlds Biggest Lie wrote:
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No, I don't.
\

It's the final scene of "Longtime Companion", the first feature film dealing with the beginning of the HIV plague.

They've got the whole thing on YouTube. It's worth watching.

http://www.youtube.com/watch...
Just poppin in for a bit

Santa Cruz, CA

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#46
Jan 18, 2013
 
Lililth_Satans_Bore wrote:
<quoted text>Josh they would use a vector like Ad-5 to carry the genes for the protein, not HIV
Gotcha! My favorite little foulmouth!

You just tipped your hand.

You KNOW stuff.

(flying tackle huggles)

“I Am No One Else”

Since: Apr 12

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#48
Jan 18, 2013
 

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NoQ wrote:
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Yea you fking perverted Freaks stick together. Nasty A$$ creatures.
You are jealous of their solidarity, well, since you bigots are so hateful you'll turn on each other in a heartbeat for a beer. It's easy to see why.

“Live and let live”

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#49
Jan 18, 2013
 
Lililth_Satans_Bore wrote:
<quoted text>Josh they would use a vector like Ad-5 to carry the genes for the protein, not HIV
Ah, I see. So they would use a viral shell after all, but the modifications are made to the protein produced inside cells because of HIV infection. At first, it sounded like the therapy would modify the virus itself during replication, therefore producing a subsequent generation that expresses the modified protein during replication. This is just a kind of gene therapy then. It's still questionable whether it would work because of the body's defenses, and with AIDS, immune suppressants to increase the effectiveness of the gene therapy would be out of the question.

Regardless, I wonder if this is following up on past research into the CKR-5 mutation. It sounds like it. That particular mutation causes production of proteins that interfere with the virus's life cycle.

“Luke laughs at hypocrites!”

Since: Sep 10

Palm Springs, California

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#50
Jan 18, 2013
 
Just poppin in for a bit wrote:
<quoted text>\
It's the final scene of "Longtime Companion", the first feature film dealing with the beginning of the HIV plague.
They've got the whole thing on YouTube. It's worth watching.
http://www.youtube.com/watch...
I can't. That particular scene is the most heart wrenching thing I have ever seen on film and made me more sad than almost any movie I have ever seen.

“Luke laughs at hypocrites!”

Since: Sep 10

Palm Springs, California

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#51
Jan 18, 2013
 

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NoQ wrote:
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Yea you fking perverted Freaks stick together. Nasty A$$ creatures.
You do realize that their solving the HIV problem will change ALL of medicine, don't you? If they can cure a VIRUS, which have before been impossible to cure, all things change for the better for everyone.

“I Am No One Else”

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#54
Jan 18, 2013
 

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NoQ wrote:
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Queers and Freaks are as much bigots as anyone. And I'm dam sure not jealous of you perverts.
Yes, you are plainly jealous of their solidarity and the support they get from the rest of us. They are not bigots, though some of them probably are, when you generalize like you do, you betray that you are a hatemonger.

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#56
Jan 18, 2013
 
I still maintain that HIV and STD's are the results of Biological Warfare. All the nonsense of it being "punishment" for unacceptable behavior;is just that,nonsense,in my opinion.

Since: Jan 08

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#58
Jan 18, 2013
 

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NoQ wrote:
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You're an ldiot, shut up.
I disagree. I may not be 'gifted;'but,I have an IQ of 130,hardly an 'idiot.' P.S. Why don't you research some of the covert activities that were undertaken during WWII on this subject. Perhaps,it just might increase your IQ,Sir.

“I Am No One Else”

Since: Apr 12

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#59
Jan 18, 2013
 

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NoQ wrote:
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Say what you want about me, but you've been on here long enough to know that 8 out of 10 HO:MOS hate Christians and make no bones about it. They're not religious because of their lifestyle and they are bigots, just as you say I am. Of course, since you're in the same freak group, you'll deny or justify their actions. Ain't that right????
Aw, you are so jealous, such a sad state that your hatemongers don't even like you.

“Together for 24, legal for 5”

Since: Sep 07

Littleton, NH

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#60
Jan 18, 2013
 

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STEPHMAR wrote:
I still maintain that HIV and STD's are the results of Biological Warfare. All the nonsense of it being "punishment" for unacceptable behavior;is just that,nonsense,in my opinion.
There is archeological evidence of HIV in Africa in the nineteenth century. So I think the conspiracy theorists are going to have to move on.

I'm not sure which other STD you might be referring to, but the most "popular" varieties have been well-known since at least the days of western imperial power.

“I Am No One Else”

Since: Apr 12

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#65
Jan 18, 2013
 

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NoQ wrote:
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I see you avoided the question altogether. HaHaHa. What more can you expect from a freak. At least you didn't have to lie to me by answering. LMFAO
I find it sad that you even care so much about what other people do in their own private rooms. Why do you care? Are you searching for that gay lover? That would be the only reason you would want everyone else to be gay.

Since: Mar 11

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Jan 18, 2013
 

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NoQ, what did a GLBT person ever do to you, personally, to make you so hateful?
Baby Jade

Springfield, MA

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#70
Jan 18, 2013
 

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Pattysboi wrote:
NoQ, what did a GLBT person ever do to you, personally, to make you so hateful?
You, have been REPORTED!

“Together for 24, legal for 5”

Since: Sep 07

Littleton, NH

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#71
Jan 18, 2013
 
For what?

“Together for 24, legal for 5”

Since: Sep 07

Littleton, NH

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#73
Jan 18, 2013
 

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NoQ wrote:
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Personally, nothing. I just think it's terribly wrong and disgusting.
You mean you're so titillated that you can't keep your mind off of gay sex.
As for being so hateful, well, I voice my opinion, some don't like it, they come at me, I come back at them. Then when you and others decide to report, they delete my post and try to ban me, but they can't. That just fuels the fire, then I just come back stronger each time. It's no big deal that they delete my post but it's just the principal of the thing since there's some on your side that gets bye with anything, especially Lililth. She's every bit or worse as bad as I am. Before you say I'm whining, I'm not. I could care less if nothing changes, if it does, then so be it. You ask, I told you.
In other words, you turn your self-hatred out on others.

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