What's significantly lacking is quantification and confirmation of rate of change per generation for eukaryotes, similar to how we know that after 50,000 generations, bacteria are still bacteria.
Evolutionary ROC is not a stable fixed thing in any life form. ROC will depend upon genome length, environment, conserved areas, exposure to mutagens.......
So what is lacking will continue to be lacking. We will learn to understand the variable better but they will still be (ahem) variable.
As bacteria are part of the food chain we will have bacteria for as long as we have other life forms.