FDA warns about 'stay awake drug' Pro...

FDA warns about 'stay awake drug' Provigil

There are 53 comments on the Medical News story from Oct 28, 2007, titled FDA warns about 'stay awake drug' Provigil. In it, Medical News reports that:

The U.S. Food and Drug Administration has issued a warning in connection with the drug Provigil because of dangerous side effects. via Medical News

Join the discussion below, or Read more at Medical News.

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sean

Central District, Hong Kong

#60 Jun 10, 2011
whitefag to man in HK wrote:
Before Modalert I was sort of living inside a dream. I always go out onto the streets and people laugh at me in my face and I scratched my head.(later I found out because I am too slim and too pale. But where I live every man is dark skinned and buff. This is the reality of Hong Kong don't believe movies.) So after Modalert I started "wake up to life" so to speak and join my local gym/tanning bed and get serious so I end up quite manly (and the whole time I take Modalert even now.).... Now as I go out on the streets the rest of men they don't dare to stare at me anymore because I am now like a cantonese-white monster to them. I love this stuff called Modafinil (or Modalert in my case.) I'm storming all over HK and it will be fun even if I end up in prison? Well, hope not ...
where do we get provigil or modafinil in hk exactly?
Sara

Janesville, WI

#64 Jun 18, 2011
PS - when I say I couldn't get any in S.E. Asia I just mean the doctors and hospitals did not have any at all. The only way for me to get it was ordering online.
The Legal Pharmacy

Bilston, UK

#65 Jun 26, 2011
http://hosted.comm100.com/Forum/Provigil-Moda...
I tried sniffing it and I got extreamly nervous and high. Not a happy high but really edgy. But then coke always made me real edgy and nervous as opposed to high and happy. I always feel I need a stiff drink to come down and sleep as too much Provigil really stimulates the head off me!
I buy it quite cheap. It is not a very expensive drug to buy generic. Makes me want to pooh a lot too!

Since: Jul 11

Cleveland, OH

#67 Jul 22, 2011
One BIG problem with buying Provigil (Modafinil) without a prescription is jail. It is a Schedule IV controlled substance. Possession can get you busted. Yea you probably wonÂ’t do time but who needs the hassle and legal bills. The same company (Cephalon) makes Adrafinil (brand name Olmifon). Adrafinil is completely legal. Basically they are functionally equivalent. Adrafinil metabolizes into Modafinil. Cephalon makes both but only spent money getting Modafinil FDA approved (by prescription only). Adrafinil dropped through the cracks (legally). It is sold in France. For delivery in the US and Canada see: http://awakebrain.com/modafinil.htm

Since: Feb 12

Gateshead, UK

#70 Feb 9, 2012
Do you search to get generic Modafinil?
I recommend you to visit Sheffield Modafinil. If you want to get it just in time and high quality then Sheffield Modafinil is the best.
Bruce Kimzey

Shingle Springs, CA

#71 Mar 4, 2012
I was one of those "one-out-of-a-million " people who died, or should have, as a consequence of having what is known as a Delayed Hypersensitivity Reaction to Provigil.

It was the consensus of the many doctors who worked to save my life that my reactions - hallucinations, delusions, hypotensive crisis, anaphalactic/distributive shock, multiple organ failures, hypoxic-ischemic syndrome, encephalopathy, cardiomyopathy - that my odds of surviving had been somewhere between 1000 to 1 and 10,000 to 1.

Every doctor who saw me at that time was at a loss to explain what had caused me to, apparently spontaneously, to drop into the death spiral that I did.

At the the time of my reaction, my recent commencement of Provigil had been doubled in dosage the day before and I had taken my first dose at approximately 2:00 pm that day. 10 hours later I was already rapidly closing in on a quick death.

Due to my extended unconsciousness there was no awareness of the increased dose nor any suspicion that an apparent one in a million reaction had occurred to me.

Here is the problem - when odds like 1 in 1,000,000 are tossed about, what they are based upon analysis of those patients who actually survived their ordeal - for those who died, a chemical cause of daeth is highly unlikely to be uncovered unless foul play has been suspected.

As for the people who face the medical conditions I did, the corollary of my having beaten a minimum 1 out of a 1000 odds is that 999 out of 1000 will not have beaten it.

So when we accept the estimate of 1 out of 1,000,000 we must build in the fact that, at best, 999 out of 1000 instances of delayed hypersensitivity to Provigil will end up unidentified simply because those folks did not live to be followed up extensively as I was. So suddenly, the odds become, at the very best, 1 out of 1000 that you will die.

That may seem like a small number but if you consider than 5,000,000 begin taking provigil or nuvigil (they are the exact same drug) per year, one out of 1000 would amount to 5,000 people per year killed by this deadly drug.

For those who actually have Narcolepsy, I could understand that this might be a risk which they would be justified in taking since narcolepsy can be so disabling. For others who seek merely a boost out of doldrums and sleepiness you must ask yourself whether it is worth dying for to obtain a uestionable amount of benefit.

There are many reports throughout the Internet which speak with positivity about Provigil. Interesting, the number of such comments seem to rise significantly around the beginning of 2008, very shortly after the FDA publicized the data which it had been hanging onto for several years.

I would say that of those positive comments I have read, and I have read many comments on many sites, fully 40% of them report that 'it gave me my life back' in very nearly those exact words.

Until recently Cephalon was lead by a ruthless megalo-maniac who was ultimately fired for malfeasance. Are you so naive as to believe that there are not companies which engage in planting 'ringer' reviews in order to counteract bad news elsewhere.

Do what you want, but know that if this drug kills you, no one will ever be the wiser, and if there are people who depend upon you for support they will have no place to turn in order to obtain compensation for their loss.

A far, FAR safer alternative is dextroamphetamine, "Dexedrine" a drug which has been around for decades and despite the scare stories about dependency and addiction rarely cause either so long as they are used orally.
organa

Shingle Springs, CA

#72 Mar 4, 2012
Yeah right

Since: Mar 12

Columbia, SC

#73 Mar 13, 2012
Bruce,

Thank you for sharing-that is very scary. Which of the symptoms did you have?
Thanks

Leo
modafinil

Lancaster, UK

#76 May 20, 2013
asdfdsaf
myname

UK

#77 May 24, 2013
Weed is safer.
Miriam123

London, UK

#78 Oct 21, 2013
myname wrote:
Weed is safer.
...but on weed you dont get any work done lol
rob

Bowling Green, KY

#80 Jul 1, 2014
Joakim Hansson wrote:
Provigil litterally saved my life. NO SIDE EFFECTS (except insomnia, sure it is indeed a pill for narcholepsy so that make sense..), but that fortunately goes away after a while. I also wanna add that it sure helped my depression. No sucidal thoughts nor any fuckitol thoughts... I consider it 2 b Gods gift.
Are you still taking provigil and are you happy with it. I just started it and having a little trouble adjusting to it. I find myself having to take a half tab in the afternoon which helps. I realize you made this post in 2009 so you prob won't see this.
David R

Allentown, PA

#81 Jul 25, 2014
Once a drug changes your brain for good, it's hard for your brain your get back to normal again. My dotor prescribed me provigil and itdid absolutely nothingfor me.

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