Non-Small Cell Lung Cancer Patients 65 And Older Should Be Considered For Therapy
There are 1 comment on the Medical News Today story from Oct 17, 2012, titled Non-Small Cell Lung Cancer Patients 65 And Older Should Be Considered For Therapy. In it, Medical News Today reports that:
Until there are more validated biomarkers to direct treatment decisions, many physicians use patient age to decide what therapy to give their patients.
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Since: Dec 05
#1 Oct 18, 2012
In regards to there being more validated biomarkers to direct treatment decisions, functional profiling analyses already uses real-time assessment that BATTLE is using. The approach involves real-time assessment of "fresh" living cancer tissue and endothelial cell behaviors in the presence or absence of anti-cancer or anti-angiogenic drugs.
This method accounts not only for the existence of genes and proteins but also for their functionality and for their interaction with other genes, other proteins, and other processes occurring within the cell.
Patients would certainly have a better chance had their cancer been "chemo-sensitive" rather than "chemo-resistant," where it is more apparent that chemotherapy improves the survival of patients, and where identifying the most effective chemotherapy would be more likely to improve survival for the elderly.
Truly personalized care represents the application of validated predictive models to select candidates for specific therapies. Good outcomes can then be ascribed to the intelligent selection and application of effective treatments.
What genomic investigators are expecting their patients to say to them is "You may not be able to treat me any better, but I like the way you think." What informed patients should be saying instead is, "I don't care how you think. I want you to treat me better!"
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