Has Anybody Used FLUOROURACIL 5% Cream?

Has Anybody Used FLUOROURACIL 5% Cream?

Posted in the Dermatology Forum

First Prev
of 21
Next Last

“Shoot for the stars”

Since: Dec 10

Planet Earth

#1 Feb 23, 2011
Hi everybody! I went to the Dermatologist yesterday morning and he told me that I had a lot of sun damage on my face. I've got brown spots that are precancerous. I've read articles on the cream and got scared of what it does and how unsightly some of the people in the photos were from the cream. Of course all the photos were of people that look 65 and older. I'm 49 with fair skin, blue eyes and blond hair. Can some of you folks give me some feedback if you used the medication?

Thank You,
Earth Child
Jammer

United States

#2 Feb 24, 2011
Yes Earth Child, I am in my 2nd week of using fluorouracil 5% cream. I used it on my entire face and a little on my neck below my ears. It didn't do much the first 3 or 4 days. Just some red spots. After 5 days, it began to really turn red. After 1 week I looked like I had a really bad sunburn with some red splotches. Now, 14 days later, I am starting to slough off skin and it is beginning to dry and feels like my face is cracking every time I smile or yawn. I was told to use it for 4 to 6 weeks and that after discontinuing treatment, I would continue to stay that way for about 2 weeks. I believe it is going to be worth it to get rid of all the AK's (or at least 90% of them). PS you will need some moisturizer for delicate skin after 1 week to ease the cracking and dryness. I had AK’s (precancerous) that I didn’t even know about. This stuff will “light them up” and destroy them.

“Shoot for the stars”

Since: Dec 10

Planet Earth

#3 Feb 24, 2011
Jammer wrote:
Yes Earth Child, I am in my 2nd week of using fluorouracil 5% cream. I used it on my entire face and a little on my neck below my ears. It didn't do much the first 3 or 4 days. Just some red spots. After 5 days, it began to really turn red. After 1 week I looked like I had a really bad sunburn with some red splotches. Now, 14 days later, I am starting to slough off skin and it is beginning to dry and feels like my face is cracking every time I smile or yawn. I was told to use it for 4 to 6 weeks and that after discontinuing treatment, I would continue to stay that way for about 2 weeks. I believe it is going to be worth it to get rid of all the AK's (or at least 90% of them). PS you will need some moisturizer for delicate skin after 1 week to ease the cracking and dryness. I had AK’s (precancerous) that I didn’t even know about. This stuff will “light them up” and destroy them.
Thank You Jammer! I haven't used it yet. My Derm. Doc. wants me to use it all over my face 2X a day for 15 days and then stop. I have what you have Jammer. I was never a tanning person, but I had a lot of blistering sunburns when I was a little kid. I really appreciate you responding because you've given me some encouragement to use the cream and I'll start using it tonight. Please keep in touch.

Thank You,
EC

“Shoot for the stars”

Since: Dec 10

Planet Earth

#4 Feb 25, 2011
I started the Fluorouracil treatment and noticed itching on my face and ears after my first application last night. Itching is one of the side effects of the medicine. I have not noticed any redness yet, but I'm sure that will appear after a few more applications.

I'll be posting updates so that people who are going to use this medicine will at least have some idea of the progress and personal experience I'm having on my skin with this treatment. I've read articles on this medicine, but I haven't found any patient feedback about this treatment. I am thankful Jammer responded to my post with his/her personal experience using the FLUOROURACIL 5% cream.
Jammer

United States

#5 Mar 2, 2011
Hello Earth Child,
How is it going?
I am in my 20th day and I think I'm gonna have to pull my face off. It feels like it is cracking in about 10 pieces. I haven't had a good night's sleep since last Saturday. I keep putting moisturizer on it and it keeps drying out and cracking. I finally found some stuff that doesn't burn and stays on a long time. It's called "Aquaphor". It seems to do the job although it's mainly petroleum jelly I think.(I sure do look red and shiny).
A good cleanser I found is "Aveeno Ultra Calming Foaming Cleanser". It is gentle.
After your face starts geting red and irritated, make sure your moisturizer says "for sensitive skin", cause that's what it's gonna be!

BTW, I am 65 year old male.
Hope your doing well.

“Shoot for the stars”

Since: Dec 10

Planet Earth

#6 Mar 2, 2011
Jammer wrote:
Hello Earth Child,
How is it going?
I am in my 20th day and I think I'm gonna have to pull my face off. It feels like it is cracking in about 10 pieces. I haven't had a good night's sleep since last Saturday. I keep putting moisturizer on it and it keeps drying out and cracking. I finally found some stuff that doesn't burn and stays on a long time. It's called "Aquaphor". It seems to do the job although it's mainly petroleum jelly I think.(I sure do look red and shiny).
A good cleanser I found is "Aveeno Ultra Calming Foaming Cleanser". It is gentle.
After your face starts geting red and irritated, make sure your moisturizer says "for sensitive skin", cause that's what it's gonna be!
BTW, I am 65 year old male.
Hope your doing well.
Hi Jammer!
Well, I have not had any reaction yet. I'm on my 6th day and all I've noticed is that a few of my nickle sized brown spots are getting little opaque white spots. No redness yet, but I'm sure that will be coming.
I talked to the nurse at my Derm Doc's office and she said the Dr. only wants his patients to use Vaseline for the dryness and that it will help with scar prevention. So you're fine with the Aquaphor. I purchased Cetaphil cleanser today to wash my face with.
I wonder if the cream helps with spider veins (telangiectasia)? I have quite a few around the brown spots that I have. Do you have any spider veins and have you noticed them going away?
Let's please keep in touch with our progress. EC
Firefly

Collingwood, Canada

#7 Apr 9, 2011
Hi Guys,
I have never posted anything before but this morning I searched the web to see if I could find more info on the cream that my dermatologist prescribed and your link popped up....perfect timing. I too have fair skin, freckles, blonde hair, blue eyes, I'm 42.
My Dr wants me to apply cream on my back, upper chest and face. She said to work in stages, not all at once...so, last night I started with my chest. I applied cream last night so it's too early to give you any feedback. Thank you for posting information...I will check in and see how everyone is doing.

“Shoot for the stars”

Since: Dec 10

Planet Earth

#8 Apr 13, 2011
Hello!
Well, the cream didn’t do anything for me. I had a couple of red spots and that was it. I was expecting blistering, redness, oozing and peeling. I go back to the dermatologist April 26th. I wouldn’t be surprised if he prescribed the cream again for me to use for a longer period of time. I only used it for 15 days this past first time.
Firefly

Collingwood, Canada

#9 Apr 14, 2011
Hi Earth Child, that's interesting...hmm.
I'm starting day 7 and I haven't noticed anything happening as well. But as you mentioned I'm still expecting to notice some changes in the days ahead. At this point, I'm only applying the cream on my upper chest....I'm nervous about applying it on my face.
Let us know how you make out on the 26th.
Axamermaid

The Valley, Anguilla

#10 May 24, 2011
Oh my, what a relief! I am on Day 19 of a 21 day regime. My gp said "you'll look hideous (check)and it may itch (that is a huge understatement), smear it all over down to bra line for one week, then dot at the spots for another two. The first week, I was traveling and more annoyed than anything else. Week two and all was revealed and it has been a serious misery since then. Unfortunately, I live in the tropics so all is a bit tricky with the heat and perspiration but there it is. Think of the alternatives. I too am using Cetaphil (have forever -wonderful stuff)to gently cleanse and then Aveeno products which do well for a couple of hours but then the silent screaming meemies start. The smart GP said I will want to panic but not to. OK, I'll try. Good luck to each of you. Now I shall return to my silent screaming - the crackling skin is not nice is it? Take care! So, Earth Child - be strong and be grateful that you have a good doctor on 'the spot' so to speak.
wiseoldbirdy2

Providence, RI

#11 Nov 7, 2011
Did any of you have success with 5% Fluorouracil cream? The lack of a success story from any of you does not encourage me to start treatment. Did any of you have success i.e. removal of basal cells carcinoma, better face skin? Interested to hear? Thanks.
wiseoldbirdy2

Providence, RI

#12 Nov 7, 2011
Axamermaid wrote:
Oh my, what a relief! I am on Day 19 of a 21 day regime. My gp said "you'll look hideous (check)and it may itch (that is a huge understatement), smear it all over down to bra line for one week, then dot at the spots for another two. The first week, I was traveling and more annoyed than anything else. Week two and all was revealed and it has been a serious misery since then. Unfortunately, I live in the tropics so all is a bit tricky with the heat and perspiration but there it is. Think of the alternatives. I too am using Cetaphil (have forever -wonderful stuff)to gently cleanse and then Aveeno products which do well for a couple of hours but then the silent screaming meemies start. The smart GP said I will want to panic but not to. OK, I'll try. Good luck to each of you. Now I shall return to my silent screaming - the crackling skin is not nice is it? Take care! So, Earth Child - be strong and be grateful that you have a good doctor on 'the spot' so to speak.
Did you have any success with 5% Fluorouracil?

“Shoot for the stars”

Since: Dec 10

Planet Earth

#13 Nov 7, 2011
wiseoldbirdy2 wrote:
Did any of you have success with 5% Fluorouracil cream? The lack of a success story from any of you does not encourage me to start treatment. Did any of you have success i.e. removal of basal cells carcinoma, better face skin? Interested to hear? Thanks.
Eventhough I did not have the reaction from the cream, the cream still worked. My doctor told me that there are people who will not get the oozing, burns and redness while the cream is doing it's job. I did have some dryness and also stinging when washing my face during the treatment. Do use the cream according to your doctors instructions because the cream does work.
Cowboy22

Boerne, TX

#14 Nov 28, 2011
I have been using FU5 off and on for over 4 years.I use it mainly on face and back of hands and occasionally on forearms. This medicine definitely works. The only suggestion I have is to be sure and use the minimum amount to just cover the area you are working on. The first time I used it, I used it pretty liberally and my face looked a mess. When my dermatologist saw it after about 3 weeks he knew exactly what I had done. Now just enough to "thinly" cover the area. I am a fair haired, light skin and got extreme sunburns when young--paying the price now but thank heavens for FU5. I sure like it better than surgery.
Sunflower

Wichita, KS

#15 Nov 30, 2011
Cowboy22 wrote:
I have been using FU5 off and on for over 4 years.I use it mainly on face and back of hands and occasionally on forearms. This medicine definitely works. The only suggestion I have is to be sure and use the minimum amount to just cover the area you are working on. The first time I used it, I used it pretty liberally and my face looked a mess. When my dermatologist saw it after about 3 weeks he knew exactly what I had done. Now just enough to "thinly" cover the area. I am a fair haired, light skin and got extreme sunburns when young--paying the price now but thank heavens for FU5. I sure like it better than surgery.
Do you check with your doctor each time you use it. I have used it for 2 weeks and my face is a mess. I did not realize there was a chance of scarring, have you experienced scarring? Will my face ever calm down? Just wondering!
bigdaddy22

Adelaide, Australia

#16 Dec 2, 2011
My dermatologist suggested I use FU5 cream on my lower lip for some "sun-spots" that keep flaring up. Eight days application was enough to make my lip sore and swollen. Then the swelling started and eventually one week later my lip had swelled to about six times it's normal size. I then began applying moisurising/healing creams like sorbolene and betadene without much success. Because the cream had produce a kind of a "burn" I even tried the sap of an aloe-vera leaf; very bitter but started the healing process. At my wife's suggestion I emulsified equal quantities of the aloe-vera (minus the outer green skin) and sorbolene and applied thatup to four or five times a day. WOW! The home-made paste was a success and within two weeks my lip was back to normal. Cheer up Earth Child 1, there's an end in sight - it just takes takes a simple home-made remedy to get there.
Charlie

New York, NY

#17 Dec 3, 2011
I'm about to start treatment on my (bald) scalp to get rid AK's (or at least 90% of them). I was very blond and am very fair skinned. I've been putting it off and now have a 4 week window (apply 2-3 weeks, then start healing).

Thank you all for these posts. The hints to apply thinly and how to soothe the effects are appreciated.
LostinParadise

Virgin Islands, U.S.

#18 Dec 4, 2011
Sunflower wrote:
<quoted text>
Do you check with your doctor each time you use it. I have used it for 2 weeks and my face is a mess. I did not realize there was a chance of scarring, have you experienced scarring? Will my face ever calm down? Just wondering!
I am starting a two week dose today, hope it is not too bad or I will work from home as I work in an attorney's office and don't want to scare off the clients...lol. I am in the islands now but originally from Wichita, hope it is getting better for you!!!!

“Shoot for the stars”

Since: Dec 10

Planet Earth

#19 Dec 4, 2011
bigdaddy22 wrote:
My dermatologist suggested I use FU5 cream on my lower lip for some "sun-spots" that keep flaring up. Eight days application was enough to make my lip sore and swollen. Then the swelling started and eventually one week later my lip had swelled to about six times it's normal size. I then began applying moisurising/healing creams like sorbolene and betadene without much success. Because the cream had produce a kind of a "burn" I even tried the sap of an aloe-vera leaf; very bitter but started the healing process. At my wife's suggestion I emulsified equal quantities of the aloe-vera (minus the outer green skin) and sorbolene and applied thatup to four or five times a day. WOW! The home-made paste was a success and within two weeks my lip was back to normal. Cheer up Earth Child 1, there's an end in sight - it just takes takes a simple home-made remedy to get there.
It's been months since I've used the cream on my face and I have to say that my skin looks great to me and my doctor said that the cream did it's job. The precancerous spots are gone and the fine lines and light brown spots I had on my face are gone too. Now I've been instructed by my doctor to use the cream on my chest due to some precancerous spots from sun damage and I'm not hesitant now after using it on my face because the results at the end are worth it.

PS....I still had some dryness and skin peeling on my face weeks after finishing the treatment, but a light touch of Vaseline worked for me until the dryness and peeling stopped.
Tom-Michigan

Mabelvale, AR

#20 Dec 5, 2011
Finished using the cream two weeks ago. This stuff works. You will look a little ugly for a while if you are using it on your face, but the end result is worth it..

Tell me when this thread is updated:

Subscribe Now Add to my Tracker
First Prev
of 21
Next Last

Add your comments below

Characters left: 4000

Please note by submitting this form you acknowledge that you have read the Terms of Service and the comment you are posting is in compliance with such terms. Be polite. Inappropriate posts may be removed by the moderator. Send us your feedback.

Dermatology Discussions

Title Updated Last By Comments
How do I treat bulging veins on forehead? (Jul '08) 8 hr Guy 1,222
Love me Instant Whitening Facial Cream 9 hr gina 2
Non-itchy widespread rash (May '08) 15 hr Neilgerard 110
Small pink bumps appearing on arms/legs that it... (Oct '09) 19 hr Naeema 410
Painful tiny bumps on fingers (Jul '11) 21 hr Chonya 292
News Fresh hope for acne sufferers (Apr '13) Tue Anonymous 6
Severe Coccyx Itching (Mar '12) Tue Piratemom 95
Tender Swollen Lump near Groin Area (Oct '08) Aug 29 bereta 532
Tiny, painless wart like bumps on hands and fin... (Jul '07) Aug 29 Barbie 544
Penis skin irritation -- already diagnosed as n... (Mar '08) Aug 28 JDW105 1,760
Small clear callous-like bumps on hand and finger (Jan '07) Aug 25 Cala 699
More from around the web