Chantix Label Updated To Warn Of Suic...

Chantix Label Updated To Warn Of Suicide Risk

There are 337 comments on the MediLexicon story from Jan 21, 2008, titled Chantix Label Updated To Warn Of Suicide Risk. In it, MediLexicon reports that:

“Patients who are attempting to quit smoking with CHANTIX should be observed for serious neuropsychiatric symptoms, including changes in behavior, agitation, depressed mood, suicidal ideation and suicidal behavior”

Main Category: Smoking / Quit Smoking Also Included In: Psychology / Psychiatry Pfizer, who make the smoking cessation drug Chantix , have updated the drug's labelling in the United States to reflect the fact ... via MediLexicon

Join the discussion below, or Read more at MediLexicon.

“Smoking UP by 1% since Chantix”

Since: Oct 07

Location hidden

#269 Feb 18, 2008
JimK,

I have bumped up a few articles for your reading pleasure. I would really love your input. So now we do know there was a mental condition that was part of the reason this incident happened. I also think it was the caffeine.

You too Sheri! You have been a great source of information and I for one appreciate your feedback. So sorry you had an experience from a bad drug too.

http://treatmentonline.com/treatments.php...
JTT

Elkhart, IN

#270 Feb 18, 2008
Man there sure seems to be a lot of people on here who oppose the use of Chantix, or any other meds as far as that goes! Nicotine changes brain chemistry simple as that and in a far more complex way than Chantix ever could. The benefits of Chantix have been proven to FAR outweigh the risks. 4 milllion people have taken it and 40 have committed suicide while taking it and this DOES NOT mean that Chantix caused the suicide. Do the math here. 40 of out 4 million! That's a whoppingly small number and no one can prove at all that these incidents are Chantix related but Pfizer, by law, has to include these warnings the same as Bayer would have to if a bunch of people taking aspirin committed suicide.

“Just Say No to Smoking Bans”

Since: Jul 07

Location hidden

#271 Feb 18, 2008
Virginia Lee wrote:
JimK,
I have bumped up a few articles for your reading pleasure. I would really love your input. So now we do know there was a mental condition that was part of the reason this incident happened. I also think it was the caffeine.
You too Sheri! You have been a great source of information and I for one appreciate your feedback. So sorry you had an experience from a bad drug too.
http://treatmentonline.com/treatments.php...
Yep, that was my experience with Effexor. Once I knew that it was the withdrawl from the drug causing the symptoms in this article, I was more determined than ever to tough it out. It took over a month. All I heard from my doctor was what a great drug it was. That was true while I was taking it. The only problem was that I would have had to take it for life to avoid the problems of withdrawl. Effexor is particularly hard to wean from because it only comes in capsules, so if you want to gradually lower the dose, you have to take the pill apart and separate the granules. Once the patient goes on a higher dose, as they always prescribe, just going to the lower dose of the drug is ineffective. I got the same withdrawl symptoms from trying that.

Since: Nov 07

United States

#272 Feb 18, 2008
JimK wrote:
Hi Virginia
Lost another one, I am starting to get paranoid. I wrote a long response and again it disappeared. You would think I would learn and cut and paste to Word before I submit.
You do not have to cut and paste your post to Word. All you have to do is, from time to time, highlight all the text (control-A) so that all the text goes black, and then copy it (control-C). The words are now in your memory should you lose the post. That is the easiest way I've found to save text. And I've had to use it occasionally. Another way is to open up Outlook Express (emails), create an email, paste it there and save it (press control-S). It will go into your drafts section, and you can delete it when it goes through. That's a good place to put links to cartoons, videos, etc.

Since: Feb 08

AOL

#274 Feb 18, 2008
Gail in Wilsonville OR wrote:
<quoted text>
You do not have to cut and paste your post to Word. All you have to do is, from time to time, highlight all the text (control-A) so that all the text goes black, and then copy it (control-C). The words are now in your memory should you lose the post. That is the easiest way I've found to save text. And I've had to use it occasionally. Another way is to open up Outlook Express (emails), create an email, paste it there and save it (press control-S). It will go into your drafts section, and you can delete it when it goes through. That's a good place to put links to cartoons, videos, etc.
Or better yet, use Windows Notepad to save links and text that has been copied to your clipboard. Just click the Start button, Run, and then type in "notepad" to open Notepad. Then you can save the files in the folder of your choice and avoid having to use an email program to save this kind of stuff.
JimK

AOL

#275 Feb 18, 2008
Gail in Wilsonville OR wrote:
<quoted text>
You do not have to cut and paste your post to Word. All you have to do is, from time to time, highlight all the text (control-A) so that all the text goes black, and then copy it (control-C). The words are now in your memory should you lose the post. That is the easiest way I've found to save text. And I've had to use it occasionally. Another way is to open up Outlook Express (emails), create an email, paste it there and save it (press control-S). It will go into your drafts section, and you can delete it when it goes through. That's a good place to put links to cartoons, videos, etc.
Thanks for the advice. However I like to use word because of the spell check feature. Sometimes when I am lazy and do not use it, it shows in the finished product. Hell, sometimes even when I use it when I read what I have posted it still does not make sense to me.
JimK

AOL

#276 Feb 18, 2008
JTT wrote:
Man there sure seems to be a lot of people on here who oppose the use of Chantix, or any other meds as far as that goes! Nicotine changes brain chemistry simple as that and in a far more complex way than Chantix ever could. The benefits of Chantix have been proven to FAR outweigh the risks. 4 milllion people have taken it and 40 have committed suicide while taking it and this DOES NOT mean that Chantix caused the suicide. Do the math here. 40 of out 4 million! That's a whoppingly small number and no one can prove at all that these incidents are Chantix related but Pfizer, by law, has to include these warnings the same as Bayer would have to if a bunch of people taking aspirin committed suicide.
I don't know that anything has been proven as of yet. You write that 4 million individuals have taken Chantix and there "only" 40 suicides and these cannot be definitively linked to Chantix. The drug has been on the market for less then two years so the jury is still out as to its effectiveness and possible long term side effects. I am not anti-medicine I am anti-incompetence and collusion. The FDA was put into place to protect the interests of the American Public, not the interests of the pharmaceutical industry. That equation has been turned upside down. Under the Prescription Drug Users Fee Act the pharmaceutical industry has been placed in the position of subsidizing their watchdog, I don't about you but that definitely seems like a conflict of interest to me. This was a poorly researched drug; too many people were excluded from the study for the study to have any validity. As I have written in the past the push to move it to the general public had less to do with profits and more to do with the general anti-smoking fervor that has reached unprecedented proportions in this country.
Finally, it's interesting that you mentioned Bayer, they have a product called Trasylol that their own research indicated that it caused heart problems and renal failure yet they kept selling it two years after they knew it was deadly. It is estimated that its continued use contributed to 24000 thousand needless deaths.
JTT

Elkhart, IN

#277 Feb 19, 2008
JimK,
I understand all your concerns mentioned above and I myself tend to be an anti-collusion type of person. With that said however I would like to address not necessarily what you've said but the general "feel" of this forum thread. As I'm sure you know ALL drugs have side effects and potential side effects and not all show up during clinical trials. That's part of what the FDA does. They have teams of people who take reports from the public of possible adverse events in post marketing of medications. There are two really good examples of medications that come to mind. Lipitor and Vioxx. I will no longer address Chantix in this thread because this thread is vehemently anti-Chantix and as far as I'm concerned those who are posting here are using the "possible" side effects of Chantix to rationalize their continued smoking. Not such a great idea in my opinion. Doctors the world over have known for years that all NSAIDS other than aspirin carried a vascular risk. But yet these medications have been used for a very long time and many can be purchased directly over the counter. There is still no definitive proof that Vioxx caused any heart attacks but because of proof that was obtained from general NSAIDS years ago then the logical conclusion was drawn that Vioxx caused heart attacks and ultimately the deaths of several people. Lawyers began to immediately draw up lawsuits not only against the makers of Vioxx but also against makers of similar medications just because a few heart attacks occurred there as well. So you see a money driven society will find any way possible to make that money back against the pharmaceutical companies because it's ingrained in us that they are evil and are out to get us. However look at Lipitor. With a plethora of possible deadly side effects it's one of the most used and researched medicines in existence and is a proven lifesaver, but just the other day I was a commercial from a lawyer (go figure) who is asking all those who took Lipitor and suffered from Rhabdomyolysis to contact him. No doubt so he could sue Pfizer over one of the most researched medicines that most of the medical community and the FDA consider safe and where the benefits outweigh the risks.
In short that is what this whole post is about -- The benefits outweighing the risks. The list of side effects of Nicotine is too long to list here but suffice it to say it's much longer than Chantix and the continued use of Nicotine from tobacco will kill you, pure and simple, it is slow suicide. If you continue to smoke it's almost a 100% guarantee that you will die from an illness cause by smoking. Chantix carries with it no nefarious reputation such as this, but I agree with you that time will tell us more about the long term safety of this medication.
JimK

AOL

#278 Feb 19, 2008
JTT

Thanks for the "well reasoned articulate argument."
I disagree with you on one point, a large number of individuals that report their side effects here and at other websites have actually quit smoking. The problem is at what cost. I cannot speak for others but what would be the purpose of taking Chantix unless you actually wanted to quit smoking.
We all know that tobacco kills. Lung cancer was practically unheard of at the turn of the 19th century. The mass marketing and glorification of tobacco use contributed to this problem. However now the pendulum has swung the other way and anyone who smokes is viewed with contempt by the anti-smoking lunatic fringe. So anything that will solve the problem that smokers create is greeted with open arms and very little scrutiny, not unlike the Patent Medicines of the late 19th, early 20th centuries.
The FDA has not helped and you have pointed out the major problem with the FDA as it now stands; and that is the Post-Marketing studies. All too often the Post-Marketing studies are in fact the real studies of a drug's effects. The FDA used to be criticized for taking too long in evaluating a drug, this changed in the 80's with the fast track process. Chantix was fast-tracked because of the "Public Hazard" created by smoking. The original purpose of the fast track program as I understood it was for individuals in danger of imminent death. As you wrote and I agree, smoking is a form of slow suicide, death is not imminent.
A large part of the problem is really not the fault of the FDA, the agency is seriously under funded and they have a shortage of qualified scientists.
What I would like to see, is that the FDA mandate that the manufacturers of any new drug include all information about the drug with the prescription, or at least a bold printed warning informing individuals where on the internet the information about the studies and the potential side effects of the drug can be found. If you do not have access to the Internet an 800 number can also be used. Had I been more aware of the potential side effects I would never have taken Chantix. If this information was more readily available at least I could have made a more informed decision as to whether the benefits outweighed the risks. This is partially my own fault; I should have researched this wonder drug before I took it.
I am not aware of the Lipitor problems that you refer too, but I am familiar with the Vioxx case. You are right there were 180,000 heart attacks or strokes, not all fatal, which were possibly linked to Vioxx; a small number when compared to the 80 million prescriptions that were written. The problem with the Vioxx case was the same problem as the Bayer case; and that was the companies withheld damaging information about the drugs from the public.
Finally, as to the attorney's I don't know about you but I look forward to those windfall checks I receive when they take the credit card companies to court. Without that windfall I would have been deprived of one cup of coffee.
Peggy

San Francisco, CA

#279 Feb 19, 2008
Post to JTT.

I understand what you are trying to say but I disagree. The people posting here are going through the SEVERE side effects of Chantix. They are not just possible side effects. The clinical trials that Pfizer performed were not diverse enough. Pfizer is now recruiting for studies to be done on people who drink, have psych problems etc. This drug has been pushed through to the public before it was ready. There must be more studies done before it can be really effective. They don't even know what would happen when taken with other medication because there are no studies on it. In my opinion, Pfizer has made us the guinea pigs. The testing is being done on the people that are taking it.

Also this and other web sites about the problems is because the people that are going through this have no where else to go to get help. The Drs are of no help because they were just as uninformed as the people who are/were taking the Chantix. There are no answers out there for us, so we look to one another.

My husband is one of those that had the severe problems. It seems all of them. He even tried to commit suicide...twice. This is a person that does not drink, do illegal drugs or had any psych problems. We have a happy marriage and two wonderful boys. We have been through hell and back with this prescription. The Drs answer to the side effects was to put him in the pscyh ward. It was a nightmare.

Now just to let you know, he quit smoking cigarettes. He did not smoke while he was taking the prescription except for the week that he was allowed.

Also I am curious as to what the long term effects are on the brain with this drug. My husband has been off of Chantix for a little over two months and he recently went through another rage/violence/suicide episode.
JTT

Elkhart, IN

#280 Feb 19, 2008
To Peggy and JimK. First let me say that I am sorry so many of you are having problems with Chantix. And to JimK, the argument was nice :)

The point I'm trying to make is that you guys are the real rarity. I've known a lot of people including myself who quit smoking by taking Chantix with no adverse effects. Because you are the minority your voices aren't being heard and that really is a shame. I hope that you all benefit in some way from any settlement that might come about. The only trouble I have with all of this is that a few people who really did have negative effects will be overshadowed by the tons of those who will come forward with false stories just to try to collect money. It will happen, in fact it's inevitable. Pfizer is big and has extremely deep pockets. Again, I'm sorry to hear about the negative effects you all have experienced but I am glad to hear that the majority are smoke free.

“OWNERS CHOICE = PATRONS CHOICE”

Since: Jun 07

United States

#281 Feb 19, 2008
To all you anti's who tried to push this chantix on smokers, I hope you can live with yourselves for causing the deaths of those who committed suicide while using this drug....

We said a long time ago that chantix was dangerous, but you didn't believe us, you just wanted your way,,,,push, push, push. Their deaths are on your souls. And you will pay for it later.... I know not how, only that you will. You anti's make me sick... you will say and do anything to get your way..even kill.

JUST WALK AWAY, IT ISN'T HARD.
Debra

San Antonio, TX

#282 Feb 21, 2008
I have smoked for 31 years. I was told I have pre-cancerous lesions in my mouth. they have a good chance of clearing up if I quit smoking. I'll try to quit. Taking chantix. However, as much as I am put down, humiliated, treated as a 2nd class citizen, maybe I would put my life on the line to stop smoking so you non smokers would get off my back. So, looks like we ALL have a part in what goes wrong.
JimK

AOL

#283 Feb 22, 2008
JTT wrote:
To Peggy and JimK. First let me say that I am sorry so many of you are having problems with Chantix. And to JimK, the argument was nice :)
The point I'm trying to make is that you guys are the real rarity. I've known a lot of people including myself who quit smoking by taking Chantix with no adverse effects. Because you are the minority your voices aren't being heard and that really is a shame. I hope that you all benefit in some way from any settlement that might come about. The only trouble I have with all of this is that a few people who really did have negative effects will be overshadowed by the tons of those who will come forward with false stories just to try to collect money. It will happen, in fact it's inevitable. Pfizer is big and has extremely deep pockets. Again, I'm sorry to hear about the negative effects you all have experienced but I am glad to hear that the majority are smoke free.
Thanks for the reply. I am not looking for a large settlement or anything of that nature. All I am looking for is the truth to be exposed, and that is this pill was pushed out to the general public before it was adequately tested. I know with the anti-smoking attitude that has run amok in our country, that this is the only reason that this poison was fast tracked by the FDA. As a smoker I am tired of being the target of these over zealous bigots. I do not want to be a guinea pig and I would have appreciated more up front information from Pfizer and the FDA. I want whoever approved this drug for fast track approval to be held accountable. I will not be satisfied until this person or persons are held accountable. I want this person's life to be as miserable as my life has been for the last 6 months. Then and only then will I feel some degree of satisfaction. This person or persons deserves to burn in the fires of hell. These people are evil incarnate and they deserve to pay for their sins. I will be avenged. Their anti-smoking bias has ruined my life as well as those of other individuals who have taken this drug with the hopes of improving their lives. I am not convinced nor will I be convinced that these people were not fully aware of the potential side effects that this drug was able to perpetuate on the smoking public. Their over zealousness has unleashed a product on the American smoking public that is tantamount to genocide. Their judgement day is coming but not soon enough. I will pursue this until such time that these charlatans are exposed for the fools that they are. When I see their lives ruined, only then will I feel some degree of satisfaction. Whether it is a Pfizer executive or an official at the FDA I want this person exposed and I want them to feel the full misery of my last 6 months.

Knit one,pearl two.

“Just Say No to Smoking Bans”

Since: Jul 07

Location hidden

#284 Feb 22, 2008
JimK wrote:
<quoted text>
Thanks for the reply. I am not looking for a large settlement or anything of that nature. All I am looking for is the truth to be exposed, and that is this pill was pushed out to the general public before it was adequately tested. I know with the anti-smoking attitude that has run amok in our country, that this is the only reason that this poison was fast tracked by the FDA. As a smoker I am tired of being the target of these over zealous bigots. I do not want to be a guinea pig and I would have appreciated more up front information from Pfizer and the FDA. I want whoever approved this drug for fast track approval to be held accountable. I will not be satisfied until this person or persons are held accountable. I want this person's life to be as miserable as my life has been for the last 6 months. Then and only then will I feel some degree of satisfaction. This person or persons deserves to burn in the fires of hell. These people are evil incarnate and they deserve to pay for their sins. I will be avenged. Their anti-smoking bias has ruined my life as well as those of other individuals who have taken this drug with the hopes of improving their lives. I am not convinced nor will I be convinced that these people were not fully aware of the potential side effects that this drug was able to perpetuate on the smoking public. Their over zealousness has unleashed a product on the American smoking public that is tantamount to genocide. Their judgement day is coming but not soon enough. I will pursue this until such time that these charlatans are exposed for the fools that they are. When I see their lives ruined, only then will I feel some degree of satisfaction. Whether it is a Pfizer executive or an official at the FDA I want this person exposed and I want them to feel the full misery of my last 6 months.
Knit one,pearl two.
At least they have taken the commercials off the air. It would be hard to sell a product via tv if you had to mention that one might kill himself or others while taking the drug. I agree with all that you said and can only hope that Phizer and the FDA are held accountable. Every drug presents risk, but when you consider that Phizer did not include any smokers with known psychological problems in its trials, it sends signals that they knew it could be a big problem for those people and for many others...and they still rushed it to market. Greed is evil. Best wishes to you.
JimK

AOL

#285 Feb 23, 2008
Sheri wrote:
<quoted text>
At least they have taken the commercials off the air. It would be hard to sell a product via tv if you had to mention that one might kill himself or others while taking the drug. I agree with all that you said and can only hope that Phizer and the FDA are held accountable. Every drug presents risk, but when you consider that Phizer did not include any smokers with known psychological problems in its trials, it sends signals that they knew it could be a big problem for those people and for many others...and they still rushed it to market. Greed is evil. Best wishes to you.
Sheri

Thanks for the response, however it is more then just greed; it is the pervasive witch hunt mentality that exists in America today that allowed this drug to be approved in the first place.

JimK

“Just Say No to Smoking Bans”

Since: Jul 07

Location hidden

#286 Feb 23, 2008
JimK wrote:
<quoted text>
Sheri
Thanks for the response, however it is more then just greed; it is the pervasive witch hunt mentality that exists in America today that allowed this drug to be approved in the first place.
JimK
You are exactly right. In time, it will be their undoing also.
Nana2

Ware Shoals, SC

#287 Feb 23, 2008
Debra wrote:
I have smoked for 31 years. I was told I have pre-cancerous lesions in my mouth. they have a good chance of clearing up if I quit smoking. I'll try to quit. Taking chantix. However, as much as I am put down, humiliated, treated as a 2nd class citizen, maybe I would put my life on the line to stop smoking so you non smokers would get off my back. So, looks like we ALL have a part in what goes wrong.
Dear Debra: Good luck to you in getting rid of the pre-cancerous lesions in your mouth. I hope you are seeing a really good doctor. Honey, we smokers are all being treated as social pariahs. We are not the bad people here...remember that, please. Do you have anyone in your family that you can discuss this with...that would help you to see just how the anti-smoking nuts are trying to manipulate all we smokers...they are the worse sort of human beings on this earth. Please do not take this horrible drug that is out now...the drug companies do not care what happens to the people who use their drugs...they are only interested in making lots of money. Good luck to you sweetie & I am praying for your recovery & that you will not allow these anti-smoking idiots get you down. I just ignore them & go my own way. If someone doesn't want to be around you because you smoke...then they are not a 'friend'. God Bless You.
Are Smokers

AOL

#288 Feb 23, 2008
Debra wrote:
I have smoked for 31 years. I was told I have pre-cancerous lesions in my mouth. they have a good chance of clearing up if I quit smoking. I'll try to quit. Taking chantix. However, as much as I am put down, humiliated, treated as a 2nd class citizen, maybe I would put my life on the line to stop smoking so you non smokers would get off my back. So, looks like we ALL have a part in what goes wrong.
Sounds like you will put your life on the line if you continue to smoke. Pre-cancerous lesions can quickly turn into mouth cancer. Mouth cancer is not pretty and can be fatal.
Are Smokers

AOL

#289 Feb 23, 2008
Nana2 wrote:
<quoted text>
Dear Debra: Good luck to you in getting rid of the pre-cancerous lesions in your mouth. I hope you are seeing a really good doctor. Honey, we smokers are all being treated as social pariahs. We are not the bad people here...remember that, please. Do you have anyone in your family that you can discuss this with...that would help you to see just how the anti-smoking nuts are trying to manipulate all we smokers...they are the worse sort of human beings on this earth. Please do not take this horrible drug that is out now...the drug companies do not care what happens to the people who use their drugs...they are only interested in making lots of money. Good luck to you sweetie & I am praying for your recovery & that you will not allow these anti-smoking idiots get you down. I just ignore them & go my own way. If someone doesn't want to be around you because you smoke...then they are not a 'friend'. God Bless You.
Dear Nana2.
Remember not to bring your gman relative into this.
Now, the woman you are responding to is dealing with a potentially life threatening condition brought on by smoking. If she continues to smoke, the probability is good that she WILL die. I would imagine that she has tried numerous ways to quit over the course of 31 years. Most smokers who have smoked that long do try and quit. Many people have taken Chantix and been successful in quitting. WHY does it SCARE you when smokers talk about quitting? Especially when the smoker is dealing with a significant health issue? You are so addicted to nicotine that you cannot even see straight. You can no longer smell, so you have no idea how bad you, your house, your car and anywhere you happen to be stink.You are so afraid of dealing with your own addiction that you become terrified when someone else deals with it. I quit smoking YEARS ago. I am still alive and happy. I can breathe. I can walk. I can RUN now. Distances. Like MILES. I can hike in the mountains. WHY does this scare you so bad? WHY does the idea of going without a smoke for the duration of a meal or the duration of a drink scare you? You really need to look at that. You are supporting a product-cigarettes- and an activity-smoking- that kills more people worldwide each year than Hitler did in his death camps during the entire war.

Tell me when this thread is updated:

Subscribe Now Add to my Tracker

Add your comments below

Characters left: 4000

Please note by submitting this form you acknowledge that you have read the Terms of Service and the comment you are posting is in compliance with such terms. Be polite. Inappropriate posts may be removed by the moderator. Send us your feedback.

Medicine Discussions

Title Updated Last By Comments
News Hemorrhoids Home Treatment (Jan '13) 8 hr mari 41
News Namibia: Illegal Abortions Common Despite Risks (Jan '10) 9 hr lola 38
How to Know Which Counterfeit Meds? 9 hr theoblais 14
News Nihon University announces first international ... 18 hr IRADRUDAEGUMIDEBD... 2
News Smoking and vaping bills in Sacramento flirt wi... 18 hr I think 3
News Trauma Survivors Who Become Superstars 20 hr Jaimie 2
News Poor sleep habits are linked to problems with s... 21 hr Jaimie 3
More from around the web