Posted in the Scabies Forum
#1 Apr 29, 2010
You are strongly advised to use the PFIZER, March 26, 2010 protocol.
Next to this (as supportive measure) you can use Octenisan wash lotion.
Octenisan is not made available in the US.
Try to find a so called MRSA active wash lotion, one that is CHEAP, one that can be used on a regular base. Select one that can claim NOT to increase resistance through so called selective pressure.
Octenisan will not promote the so called selective pressure according documentation. Also Octenisan must be kept on the skin for a minimum of three (3) minutes.
The PFIZER (March 26, 2010) unrestricted funded research advises to add one cup household bleach to a bath taken once a day, for a minimum of five (5) day's for at least thirty (30) minutes.
Why conduct unrestricted funded research?
Why are doctors asking PFIZER permission what to do?
Why conclude that a bottle of household bleach that can be found as cheap as 26 Pence, represents the only molecule that will work?
Is this an incentive to start a mass decontamination?
Against the colonization with Staphylococcus Aureus, the agent of MRSA?
Dear, dear Scientists what have you done!
About the PFIZER protocol:
Next to using the bleach baths, you are advised to use mupirocin (Bactroban) NASAL cream.
You need to apply the cream to the anterior nares of the nose.
Repeat applying a THIN layer of the cream several times per day.
Household bleach (sodium hypochlorite) is an old antiseptic.
My advise is to continue to use the protocol up to thirty (30) day's.
If you are not in the possession of a bath, you can make a weak solution in a plastic bottle and use this under the shower.
Apply the weak solution again and again.
Use gentle but sturdy scrub means, like a brush, a glove, a scrub sponge or a wet towel.
DO NOT CAUSE INJURY
Treat all body parts.
You can promote penetration by putting up a bath cap, by using latex gloves, or plastic foil to treat in particular scull, hands and feet.
The hands are the most difficult to treat reservoir.
Keep nails short.
Do not use pure bleach out of the bottle.
It may cause serious harm
Take great care with observing hygiene.
Fresh towels, fresh clothing.
Decontaminate your wash machine by adding half a cup Bleach to a hot (white) wash cycle. Use white bed sheets that can withstand a hot wash cycle.
Decontaminate COLORED fabric by adding an antiseptic to the wash cycle.
One that will not do damage to the fabric.
Decontaminate in particular hard surfaces and wet places.
Decontaminate in particular plastic shower curtains.
Include water taps, door handles, toilet walls and toilet seat.
Vacuum clean regularly, replace filters and paper bag more often.
Do not SKIP treatment, but take an extra shower with a weak household bleach suspension if you like.
Take care with all (oily) shampoo and soaps, or skip them all together.
Classic (alkalic rich) soaps are still the best.
Do not scrub skin lesions, but promote healing under a plaster.
Add classic povidone iodine if necessary.
Take time to deplete the skin of your scabies like biting biofilm.
You can not do this at once.
#2 Apr 29, 2010
March 26, 2010 (Atlanta, Georgia) Nasal application of 2% mupirocin and bleach baths were found to be more effective at eradicating Staphylococcus aureus colonization than other interventions, according to the findings of a randomized trial.
Bernard C. Camins, MD, from the Division of Infectious Diseases at the Washington University School of Medicine in St. Louis, Missouri, reported the findings here at the Fifth Decennial International Conference on Healthcare-Associated Infections 2010.
According to the researchers, a variety of strategies have been used to decolonize patients with varying results, and there are "no published data on controlled trials evaluating the optimal methods for decolonization and their efficacy in preventing recurrent S aureus infections."
Dr. Camins and colleagues evaluated the effectiveness of decolonization methods in the eradication of S aureus carriage in 193 children and 107 adults presenting with community-acquired S aureus skin and soft tissue infections.
In addition to education on personal hygiene, all eligible patients were randomize to 1 of 4 groups: no intervention (control); application of 2% mupirocin ointment to both anterior nares twice daily for 5 days; application of 2% mupirocin ointment intranasally plus daily showers with 4% chlorhexidine solution for 5 days; and application of 2% mupirocin ointment intranasally plus daily 30-minute soaks in dilute bleach water for 5 days.
#3 Apr 29, 2010
Of the patients, 68% were colonized with methicillin-resistant S aureus (MRSA) and 32% were colonized with methicillin-sensitive S aureus alone. All interventions were effective 1 month postintervention at eradicating S aureus carriage, compared with the control group.
At 4 months postintervention, only the mupirocin plus bleach bath was found to be effective at eradicating S aureus colonization (69% vs 48%; relative risk, 1.26; 95% confidence interval, 1.05 - 2.01; P =.02). All treatment groups were well tolerated, with dry skin being the most common adverse effect.
"This current study is a pilot feasibility study for a larger trial to determine whether decolonization would prevent future episodes of skin and soft tissue infection," Dr. Camins told Medscape Infectious Diseases.
"Before we completed the trial, decolonization methods were being used clinically without any scientific data supporting their use," he said. "Now that we have completed our trial, at least clinicians can feel comfortable recommending the intranasal application of mupirocin plus bleach baths in patients with recurrent community-acquired MRSA skin/soft tissue infections," he said.
Dr. Camins added that they were surprised that the mupirocin plus chlorhexidine intervention did not lead to decolonization, compared with the control group, at 4 months.
According to Keith M. Ramsey, MD, from the Brody School of Medicine at East Carolina University in Greenville, North Carolina, who attended the meeting, the addition of the diluted 30-minute bleach bath to nasal mupirocintreatments, resulting in two thirds of the S aureus carriers remaining free of carriage for up to 4 months, is a new finding, and should be explored in larger studies.
Dr. Ramsey told Medscape infectious Diseases that "it would be interesting to follow the subjects in the treatment arms to determine if any of the decolonization regimens result in differences in subsequent or recurrent clinical disease with S aureus or MRSA."
#4 Apr 29, 2010
This study was supported by an unrestricted grant from Pfizer. Chlorhexidine solution was provided by Mölnlycke Health Care. Taro Pharmaceuticals contributed generic mupirocin ointment. Dr. Camins reports being a consultant for Pfizer. Dr. Ramsey reports being a consultant for BD GeneOhm and on the speakers' bureau for MedImmune, Cubist, and OrthoMcNeil.
Fifth Decennial International Conference on Healthcare-Associated Infections (ICHAI) 2010: Abstract 502. Presented March 20, 2010.
Since: Aug 09
#5 Apr 29, 2010
..as you advise against using 'oily' soaps do you also advise against using moisturising creams during this 30 day regime?
The bleach baths obviously strip the skin of its oils but perhaps you think that is necessary yo rid the skin of 'biofilm'....?
#6 Apr 29, 2010
I have no idea what type oil would be a strategic way to replenish the skin.
If you really really need it, probably a natural Coconut or Olive oil based moisturizer, or something with a carotene.
Type: MRSA skin lotion, skin cream
As you can read antibacterial components in skin care product are antibiotic and can be the cause of selective pressure.
Ridding the skin of the biofilm with a Bleach bath may open up the pores already so much, that within hours an excess of natural skin oil on the skin will occur. This will increase again the bacterial load because now you feed the tigers, as a result you will long for another refreshment.
Expect the first three, four day's a serious increase in skin problems.
Crawl, stitch, stitch, Jesus, those "mites" are suddenly everywhere!
Keep on dissolving the polymer, and slowly you will start to gain overweight. Only cream back if you are with a particular skin condition.
And don't start to crack the skin with too excessive bath rituals.
(the skin should not start to pull)
Most pure ethereal oils will dry out the skin excessively and are not suitable as skin product, as far as I know.
Maybe Manuka honey and Shea butter based products?
I think you will discover a whole market.
Just follow the money stream!
Since: Aug 09
#7 Apr 29, 2010
'Keep on dissolving the polymer, and slowly you will start to gain overweight'
I don't understand this expression ,overweight.
Could you please do Duh Huh the courtesy of responding to his questions.
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