Rising PSA After Negative Prostate Bi...

Rising PSA After Negative Prostate Biopsy Part I: Crunching the Numbers

Posted in the Prostate Cancer Forum

prostate doc

Pasadena, CA

#1 Mar 8, 2012
One of the most pleasant phone calls I can make is to tell one of my patients that their prostate biopsy was negative…no cancer. I can often hear the sigh of relief on the other end of the line after several days of anticipation end in the best possible news. Unfortunately, at a later point in time, some of these men demonstrate a rise in their PSA. This leads to a much less festive phone call. Instead of a sigh of relief, I often hear anxiety and fear. I also invariably hear the same question:“ Doc, what do we do now?” This is actually a very important question with a complicated answer. For some men, it means a repeat biopsy. For others, in contrast, it means just repeating the PSA again in a few more months. So how do you determine how to deal with a rising PSA after a negative prostate biopsy? There are many tools that help urologists to figure out who needs a repeat biopsy in this setting. In this post, I will cover how a more detailed look at the PSA can help determine whether a PSA rise after a negative biopsy is a sign of missed cancer or simply of benign growth of the prostate.

You can find this post at:


I would also like to announce my new book,

Prostate Doc’s Guide to Life After Prostatectomy

It is a guidebook for those men about to undergo radical prostatectomy as well as those that recently went through the surgery. It covers all the common questions and issues that men have related to prostatectomy that I have encountered in my own practice and have heard from men through my blog. You can check out the book at:


As always, I hope you find it useful!

Prostate Doc

Los Angeles, CA

#3 Jun 22, 2012
What do you think about http://www.ViProsta.com for a prostate relief supplement?

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