Ciglitazone and cisplatin combination therapy for ovarian cancers

Posted in the Ovarian Cancer Forum


Madison, WI

#1 Jul 10, 2011
Combination therapy using ciglitazone and cisplatin enhances inhibited the growth of ovarian cancer in conjunction with reduction in angiogenesis and induction of apoptosis resulting from suppression of PGE2 activation through decreasing the expression of COX-2, mPGES, and EP3. The inhibitory effect of this combination treatment on growth of ovarian cancer suggests a potential to lead a novel therapeutic strategy against ovarian cancer. Details:

Austin, TX

#2 Jan 25, 2013
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