Knee Staph Infection
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GigiKneeless

Sandy, UT

#1 Mar 9, 2007
I recieved a total knee replacement in June 2005. I went fifteen months with pain and the incision not healing. In September 2006 I had the knee aparatus removed and started Vancomycan threapy for six weeks every 12 hours. I waited a month and then went into surgery to have my knee replaced but the infection was still in my leg bone. Another spacer was put in and I had another round of antibiotics. This time it was zyvox in the pill form. I have waited six weeks and now they are stalling. No treatment but lets wait another month. I do not see what that would do to help matters. In the mean time my other knee is going out and I am in pain. I need to find a new doctor that knows what he is doing. Any suggestions?
booterup

High Point, NC

#2 Mar 17, 2007
I'm really sorry to hear you are having this terrible time with infection. I don't know what to tell you other than to ask for a referral to a specialist in infectious diseases or something like that. It's obvious that you contracted an infection shortly after your TKR that is still in your body, so something else may be going on.

I do know that after my TKR, I was told that I had to get on antibiotics to even get my teeth cleaned because the slightest infection could cause my body to reject the foreign substances in my new knee. If that happened, the aparatus would have to be removed and that it would be a year before another could be put in. Believe me, I take antibiotics every time. So far, so good.

Best of luck
James

Forest, VA

#4 Apr 29, 2009
I am getting ready to have my 3rd knee joint put in in less than two years after infection, infection gets in joint they remove it than replace after 6 to 8 weeks.
Susie

Kansas City, MO

#5 Aug 2, 2009
How dangerous is it to have small children around people who have the staph infection in knees?
What precautions should be taken?
TONY NJ

Trenton, NJ

#6 Sep 27, 2009
I HAD A TKR DONE IN AUG. 01. I was diagnosed with staph infection on Oct 07. No one can tell me from what! Went back to MD that did original replacement he sent me to infectious Dr. I went in to hosp. I had my leg cleaned out left the replacement in and was put on a pic line and Vancomiasyn for 6 weeks.
I've had other opinions and the choices were take it out etc or try to get rid of it with daily doses of bactrim , an antibiotic . Here I am 2 years later still on antibiotics and hear horror stories about taking the knee out and having no guarantee the staph will come back. I am at wits end and worried sick about the coarse of action that you go through taking the knee replacement out.
Concerned

Richmond, VA

#7 Nov 5, 2009
The recommended protocol to deal with infection after TKR is to take out implant, put spacer in, give course of 6 wks IV antibiotics, and then go in to put another knee in. However, it depends on your surgeon.
My aunt had TKR in May 09 and had some issues with the incision draining and not healing properly; however, she was able to return to work the end of June.
She ended up in the hosp in Sept with pneumonia and staph infection in the knee. The surgeon went in a cleaned out infection only replacing plastic portion of the knee. She just finished 6 wks of IV antibiotics and now has started oral antibiotics for another 3 wks.
The infectious disease specialist advised us that there is a big possibility that she may need antibiotics long term and there is no guarantee that infection won't return. It is a waiting game now.
R Bagley TX

Sadler, TX

#8 Jun 5, 2010
Interested in comments about staph after TKR. My experience may benefit some having the problems. Right knee replaced in 1993 with no problems. The left TKR in 2003 resulted in staph a year after. It was opened and flooded with antibiotics, went through pic-line experience and have been on Minocycline 100mg 2x day. After 5plus years on antibiotics I have body parts turning black/blue such as finger nails, ears, nose and elsewhere. Can't determine what the long term effect of this is because there are no long term studies of the issue.
I am sure I will find out because I don't intend to let any Dr cut on my knee again.
Chrissy

Tucson, AZ

#9 Jul 6, 2010
What type of procedure do they do when you have staph in the knee replacement and it has to be removed? How long on a pic-line? how long before they are able to replace the knee again?
Karen

Egg Harbor Township, NJ

#10 Jul 17, 2010
I had a left TKR done in May 2008. A month later I had horrendous pain in my back and my knee became extremely warm. I was told I had a staph infection in my back (osteomyelitis) and knee. I attributed the infection to having had spinal anesthesia. They opened me up and cleaned the knee, three pic lines (8 weeks each time) and oral antibiotics, removed the knee and put in a spacer and then another TKR (April 2009). The osteomyelitis resolved and the infection hasn't returned in my knee, but I'm on clindamycin (300mg) daily for the rest of my life. I have blood work done every 3 months for liver and kidney function and to check my sed rate. I'm now having problems with my right knee and I'm only using medical intervention. I have several friends who have had TKR's without any problems, but I would never do it again.
Karen

Egg Harbor Township, NJ

#11 Jul 17, 2010
After they cleaned out my knee and 2 rounds with the pic lines (7 month period), my knee was removed and replaced with a cement spacer. I was in a brace and wheelchair and was able to use a walker but only put 10% of my weight on it (basically for balance). I had another pic line for 8-10 weeks during this time and then oral antibiotics. The spacer was in for 3 months before they put in the new knee. During this time they were watching my sed rates to make sure they remained low and watching any visible signs of infection. I never had any drainage (heat , abnormal swelling and minimal pain).
Dave

Grasonville, MD

#12 Aug 29, 2010
Karen wrote:
After they cleaned out my knee and 2 rounds with the pic lines (7 month period), my knee was removed and replaced with a cement spacer. I was in a brace and wheelchair and was able to use a walker but only put 10% of my weight on it (basically for balance). I had another pic line for 8-10 weeks during this time and then oral antibiotics. The spacer was in for 3 months before they put in the new knee. During this time they were watching my sed rates to make sure they remained low and watching any visible signs of infection. I never had any drainage (heat , abnormal swelling and minimal pain).
there is a new procedure for infected tkr. you take the knee out
and dont replace with anything. look up dr whiteside st louis mo
Marlene

Rancho Cucamonga, CA

#13 Sep 8, 2010
Hi Everyone,

I have just developed an infection in my TKR and am on the PICC line treatment. So far the infection seems to have subsided a whole lot but I will finish out 6 weeks and see where we go. Does anyone know if it is protocol to be given antibiotics before having any other surgical procedures (such as I did on my feet)post TKR? I am aware of the use for dental work but that is all. Thanks,
Marlene
Sarah

Fairfax, VA

#14 Sep 9, 2010
Marlene wrote:
Hi Everyone,
I have just developed an infection in my TKR and am on the PICC line treatment. So far the infection seems to have subsided a whole lot but I will finish out 6 weeks and see where we go. Does anyone know if it is protocol to be given antibiotics before having any other surgical procedures (such as I did on my feet)post TKR? I am aware of the use for dental work but that is all. Thanks,
Marlene
I am just aware of the dentist...and they told me for the rest of my life..how about you..hope you feel better.
Marlene

Rancho Cucamonga, CA

#15 Sep 9, 2010
Hi Sarah,
I wasn't told about dental work so I am glad I have learned that one. I am feeling much better, thanks.

I just want to be very sure that in the future if I need any other minor surgery that I get protected but the doctors say antibiotics aren't necessary in that case...makes no sense. This infection resulted because of my foot surgery. The timing was just too obvious.
Sarah

Fairfax, VA

#16 Sep 9, 2010
Marlene wrote:
Hi Sarah,
I wasn't told about dental work so I am glad I have learned that one. I am feeling much better, thanks.
I just want to be very sure that in the future if I need any other minor surgery that I get protected but the doctors say antibiotics aren't necessary in that case...makes no sense. This infection resulted because of my foot surgery. The timing was just too obvious.
Marlene, I have take 4capsules of clindamycin 1 hour before i have my teeth cleaned..who needs dinner (lol)
Kathy NJ

Haddonfield, NJ

#17 Oct 18, 2010
Karen wrote:
After they cleaned out my knee and 2 rounds with the pic lines (7 month period), my knee was removed and replaced with a cement spacer. I was in a brace and wheelchair and was able to use a walker but only put 10% of my weight on it (basically for balance). I had another pic line for 8-10 weeks during this time and then oral antibiotics. The spacer was in for 3 months before they put in the new knee. During this time they were watching my sed rates to make sure they remained low and watching any visible signs of infection. I never had any drainage (heat , abnormal swelling and minimal pain).
My Father is going through the same thing right now. How are you making out.
Karen

Philadelphia, PA

#18 Oct 18, 2010
Kathy NJ wrote:
<quoted text>
My Father is going through the same thing right now. How are you making out.
I'm doing alright. I can bend my knee about 90 degrees and I can only do one step at a time, but I am pretty much pain free. I see the infectious MD every 4-6 months and my sed rate is within normal limits. I am having problems with my other knee but I am treating it medically and so far it's tolerable.
I continue to take 300 mg of clindamycin daily, without any side effects. I wish your father all the best.
Dave

Martelle, IA

#19 Nov 8, 2010
I had TKR 1/26/10 and was doing great until 9/19/10. I woke up with chills and a fever and had to go to the emergency room the next day. Since I was in Las Vegas at the time they admitted me and did an arthroscopic irrigation as well as inserting a catheter to the knee to drain it for 48 hours. I had a PICC line put in and given several different antibiotics. I travelled back to Iowa 9/24 with an immobilzer and had poly replacement surgery 9/28. I am still in pain and it has been a difficult rehab knowing that the infection could resurface at any time. The CRP and sed rate markers are coming down and I am feeling better. At 56 years of age I didn't expect this infection to slow me down as much as it has. I am still in Physical therapy and walking ok without a cane, but steps are still a bit of a struggle. Does anyone know what the % of reoccurrence of the infection is after this type of treatment? I am expected to be on Levaquin and Rifampin for 6 months or more and the Drs. say it could reoccur up to a year after the antibiotics are stopped!
Tonya Oregon city OR

Aurora, OR

#20 Nov 12, 2010
I just found out that I may have staph again in my knee. I had TKR Jan 2003, and have had little problem. Now it is swollen and in much pain. Went to the Dr. he took blood and my sed rate is high. Not really sure what this all means. I had osteotomy done in 1994, that resulted in a terrible staph infection, had to go in emergency surgery to clean it out. After TKR had another staph infection caught early and treated. If any one can help me with more info I would appreciate it. I did not know that staph could come back after so many years. Now dr is talking removing the knee, spacer then replacement, but he feels since I am so young and have had so many surgeries on my knee that I may be looking at amputation in the future. This scares the bejesus out of me.
Thomas

Houston, TX

#21 Dec 7, 2010
TKR 5/3/2010 with minimal issues. Did the rehab and went back to work in 6 weeks. 8/21 went to ER due to pain and swelling resulting in inability to walk. 8/22 arthroscopic irrigation of the knee was done and then on the 25th the spacer was replaced. After 6 weeks of vancomycin pic line twice a day I'm back to work and taking Doxycycline twice a day for 6 weeks then once a day for 6 more.

All this is very scary and the surgeon acts like it's all great. They will never take an x-ray of the area where the infection started.

Has anyone gone to a second doctor and had X-rays done to establish a baseline to monitor knee over long term? Was a second doc responsive / cooperative? The Ortho seems scared to death and he's in CYA mode. I'm not interested in anything, but survival and minimalizing the already bad situation.

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