Prognosis for advanced kidney cancer with Nexavar

[searching for info]

I have a friend that was recently diagnosed with stage IV renal cell carcinoma with mets to the lung, lymph nodes and brain.

He was just started on the newly approved drug Nexavar. Does anyone know how well this new drug works on metastatic kidney cancer?

[Phil]

I have stage IV Renal cell. I started Nevavar in late November, 2005. After 2 months my scans showed signifigant shrinkage.
The side affects are not too bad.(Mainly fatigue)
I hope this helps.

[Tim]

My Dad has Kidney cancer. He had a kidney removed about a year ago, but now its back in his lungs. What is the prognosis for those who have the cancer come back somelace else?

[larry miller]

searching for info wrote:

I have a friend that was recently diagnosed with stage IV renal cell carcinoma with mets to the lung, lymph nodes and brain.

He was just started on the newly approved drug Nexavar. Does anyone know how well this new drug works on metastatic kidney cancer?

My wife has just been diagnosed with the same and is undergoing tests at a Phoenix location. She too will be put on the new drug Nexavar. We are anxious to hear any information of what we have face and how it will help us. Is there any proven places where anyone knows that we can get good advice and care.

[JSN]

My mother was diagnosed with renal cell carcinoma 7 years ago. After removal of her kidney, she was placed in the trial for Nexavar. I her case it has worked wonders. Her metastisized tumors have shrunk considerably. She is still very my alive and kicking!!!

[sue]

Tim wrote:

My Dad has Kidney cancer. He had a kidney removed about a year ago, but now its back in his lungs. What is the prognosis for those who have the cancer come back somelace else?

I can't answer your question because I have the same one, and am writing here to see if you found out anything. My mother-in-law has the same story. Thanksgiving of 2004 she had a kidney removed and now the cancer in back, 2 spots in one lung, largest 6 cm. Information we have received is so contradictory. Does anyone out there have any information on prognosis, experimental treatments, etc...

[caring daughter]

Mu father was diagnosed with kidney cancer 3 yrs ago. It has spread to lungs, spine, adrenal glands. He was on Nexavar for 3 months. In that three months it spread to the spine, the tumor is his adrenal gland doubled in size. He was taken off of it. He was extremely sick while he was on the meds. No appetite, very tired, nauseous. I hope everyone else has better results with it. He was put on it the very day it was FDA approved.

[sheri]

My mother was last month diagnosed stage 3 renal cell carcinoma and now its in her lungs, stage 4, she is suppose to go on Nexavar next week, is there any hope on this drug? Or is this just buying more time?

[Herb]

My wife has been diagnosed with kidney cancer. She goes in to have her affected kidney removed on the 7th of june.
Should we put her on nexavar at $1,000 a month?
Please advise

[budj]

have been on nexavar 4 months. tumor still the same not growing. very few side effects.

[val gray]

My husband has kidney cancer 1V and is on sorafenib he has not been feeling to well, and has also has a bleed from the bladder his bp appears to be high ,will this all settle down in time.
he has been on it 3weeks

[budj]

val gray wrote:

My husband has kidney cancer 1V and is on sorafenib he has not been feeling to well, and has also has a bleed from the bladder his bp appears to be high ,will this all settle down in time.
he has been on it 3weeks

i had fatigue at the beginning. then blisters on hands and feet. after a while they went away. fatigue stills returns on some days. the side effects i have had are manageble.

[Howie]

sheri wrote:

My mother was last month diagnosed stage 3 renal cell carcinoma and now its in her lungs, stage 4, she is suppose to go on Nexavar next week, is there any hope on this drug? Or is this just buying more time?

I've heard good things about Nexavar but even more about Sutent. In Clinicals Sutent showed tumor size reduction in around 40% of patients. Nexavar only showed reduction in 2%. Nexavar did stop growth however in 80%.

We decided to go for the 40% with my Dad who has RCC and so far great results. The tumors are shrinking. While the drug is expensive, it is worth every penny. He does have good insurance so he gets it relatively cheap.

I highly recommend investigating sutent as well as all news points to the miracous nature of this drug.

Best of luck. Life is worth fighting for!

[Howie]

Herb wrote:

My wife has been diagnosed with kidney cancer. She goes in to have her affected kidney removed on the 7th of june.
Should we put her on nexavar at $1,000 a month?
Please advise

I've heard good things about Nexavar but even more about Sutent. In Clinicals Sutent showed tumor size reduction in around 40% of patients. Nexavar only showed reduction in 2%. Nexavar did stop growth however in 80%.

We decided to go for the 40% with my Dad who has RCC and so far great results. The tumors are shrinking. While the drug is expensive, it is worth every penny. He does have good insurance so he gets it relatively cheap.

I highly recommend investigating sutent as well as all news points to the miracous nature of this drug.

Best of luck. Life is worth fighting for!

[Cathy]

My mother now 81 had a kidney taken 10 years ago due to a renel cell tumor on the out side, the whole kidney was taken at the time. In Oct 2003 she was diagnosised with renel cell cancer in the L2 and L4 lumbar region of her spine. She had Avastin treatments, which helped shrink the tumors some. She has been in hospice since Feb 2006 and is on many pain meds. I now realize this is a "long suffering evil disease".

[Herb]

My wife had her left kidney and lympth nodes removed on 06/09/2006. She now needs to go on something to head off cancer in other parts of her body. We will be offered options of therapy in 2 weeks and can someone give me the costs per month of the following?

1. Nexavar
2. Sutent
Also:
How long do you stay on it?

[budj]

both are about the same price. if you dony have ins about 4000.00 a month. doc told me as long as it works i will continue to take it. it has been working fine for me. there are some programs available to help if you qualify. check the web for nexavar info.

[Donna]

My husband is 56 years old . He had his right kidney removed 4 years ago Oct. 2005 cancer is back in his left lung and chest wall. He has been on Nexavar for 8 months now. No sign of growth or spreading of cancer so far. Side effects are managable.

[Herb]

My wife goes on Nexavar next week and I will keep all informed of her progress. At this time she is off of pain pills and has no pain but feels blue due to her unknown future. I do my best to keep her spirits up.

[Nancy]

Had kidney and tumor removed April, 2003. Cancer back in lymph node behind heart. Started Nexavar April, 2006. After 2 months, tumor shrank. Had side effects of rash all over and blisters on hands and feet, which have cleared up. My hair got very thin (I purchased a wig), but mostly feel pretty good. I'd love to hear from more people what side effects they are having (if any) and how they are managing. But Nexavar does work (along with prayer)!