quadruple therapy cured my h pylori

United States

#21 Oct 1, 2010
I am so happy to finaly have found 1 positive review about antibioutis. I was just diagnozed with h pylori and exactly: no one can even imagnie how crapy you feel when you have it. Eveybody I told they say well it doest say that is that bad and you can take antibiotics and cure it. But do you know how I feel? And reading all the bad side effects and afeter treatmant condition you can catch on? Its terible. Im terifide. I've been suffuring for couple of months and I cant take it any more. its life consuming. Sometimes I cant eat anything for 4-5 days.
Anyway.... I'm going to see my doctor tommorow to prescribe me antibiotics. Can you plese tell me more what combination of pills worked for you? thank you so much in advance. Also what was your diet while taking the antibiotics? Did you took probiotics in the same time? And the most important.. did you had side effects and what were they? Please you will be on big help if you can answer me the quiestion tonite as I'm seing my doc tommorow.
Copy of spreadsheet

Aurora, CO

#23 Oct 10, 2010
Hi Susan,
Please send a copy of your spreadsheet and any foods you ate as well to me at [email protected]


Saint Albans, UK

#24 Nov 7, 2010
I just started quadruple therapy on Saturday. Could you e-mail me your spreadsheet to [email protected]? Thanks

Ogden, UT

#25 Nov 14, 2010
I just found your post. Can you email the spread sheet to me also. I appreciate your kindness.
Colleen [email protected]
susan wrote:
hi again, just thought I would post the below information which is how I found out about the quadruple therapy:(from website:
http://digestive.niddk.nih.gov/ddiseases/pubs... )
Bismuth subsalicylate (Pepto-Bismol) coats ulcers, protecting them from stomach acid. Although bismuth subsalicylate may kill H. pylori, it is used with—not in place of—antibiotics in some treatment regimens.
In the United States, clarithromycin-based triple therapy—triple therapy, for short—is the standard treatment for an ulcer caused by H. pylori. The doctor prescribes the antibiotic clarithromycin, a PPI, and the antibiotics amoxicillin or metronidazole for 10 to 14 days. Because research shows higher cure rates with 14 days of treatment, some doctors now prescribe triple therapy for this longer period.
Bismuth quadruple therapy is another treatment strategy used in the United States. The patient takes a PPI, bismuth subsalicylate, and the antibiotics tetracycline and metronidazole for 10 to 14 days. Bismuth quadruple therapy is used to treat patients in one of several situations, including if the patient
•cannot take amoxicillin—a penicillin-like antibiotic—because of a penicillin allergy
•has been treated before with a macrolide antibiotic, such as clarithromycin
•is still infected with H. pylori because triple therapy failed to kill the bacteria
Triple therapy and bismuth quadruple therapy may cause nausea and other side effects, including
•stomach upset
•a metallic taste
•a darkened tongue or stools
•flushing when drinking alcohol
•sensitivity to the sun
Patients should discuss any bothersome side effects with their doctor, who may prescribe other medicines to kill the bacteria and cure the ulcer.
Although antibiotics can cure 80 to 90 percent of ulcers caused by H. pylori, eliminating the bacteria can be difficult. Patients must take all medicines exactly as prescribed, even when the peptic ulcer pain is gone.
At least 4 weeks after treatment, doctors test patients using a breath or stool test to be sure the H. pylori infection has been cured. Blood tests are not useful after treatment because a patient’s blood can test positive for H. pylori even after the bacteria have been eliminated.
If infection is still present, ulcers could recur or, less commonly, stomach cancer could develop. Thus, some patients need to take more than one round of medicines to kill the H. pylori bacteria. Bismuth quadruple therapy is one of several treatments used after initial treatment has failed—a strategy called “rescue” or “salvage” therapy. In the second round of treatment, the doctor prescribes different antibiotics than those used in the first round. Amoxicillin, however, can be used again to treat H. pylori infection because H. pylori resistance to this antibiotic is rare.
hope this helps.

Phoenix, AZ

#26 Dec 2, 2010
Ms Susan in Hereford.. thank you for your very encouraging words. I've been suffering for 8 months now and after 2 worthless gi drs, I found Dr. Panetta (AZ-USA). He was amazing; he found the h-pylori. I think I still have them, but a breath test on the 8th will confirm yea or nay and if I do, I'm praying the quadruple therapy works. Listening to your story gives me hope. This is a very debilitating and challenging problem. Having a good gastroenterologist makes all the difference in the world. The doctors I dealt with before Dr. P were so insensitive and dismissive. To those sufferers out there like me, perservere and don't repress your feelings or suspicions. If something feels wrong, its probably wrong. Again, Ms. Susan, I'm so happy for you that relief came and I pray the same for myself and the many in the same boat as I. dbird

Singapore, Singapore

#28 Dec 8, 2010
Hi Susan. I also suffered stomach problem for 2 years and scope revealed that my stomach had very bad inflammation and also presence of H.Pylori bacteria. Was on triple therapy which didn't work and then Quad.therapy. I felt immence relief. Unfortunately now, 2 months later, i am again beginning to feel some hot feelings in the stomach area. I will be doing a UBT next week. Plse pray for me that my results will show that the HP has been exterminated. I am at a lost.

I am so happy for you that your regime works.

Sterling, VA

#29 Jan 2, 2011
hi dears i hope you feeling good more then 5 years is that i have h pylori i approuch to many doctors they gave me deffrind prescrption but those prescraption did`t work for me like 2 week antibatis 10 days actibatics and fainally i bought matula herbal tea but it also did`t work for me one think i wanna say that never try to buy matula herbal tea becuse it dose`t work and they never say if you have h pylori in your stomach more then 2 years matula dose`t work it is a business and i now i do`t know what should i do what is the best way which i should do that if your have good experience just sent me on this e mail ( [email protected] thank you iam from afghanistan my english is not too good i hope you understand me have a great day

Laval, Canada

#30 Mar 5, 2011
Hi Susan!

Your comments are so inspiring!

I tested positive for H Pylori and opted for the "quadruple therapy" as well. My doctor told me to begin taking it Monday (as he was away from the office these past few days)...I thought it was strange that he'd say that. He told me that I will be calling him as I will not be happy when undergoing this treatment.
I was petrified and stumbled upon your comments and I must say, your story is making me feel better.

I have had that "feeling" of something being off for a year now. Constantly bloated, heartburn is crazy!(when I'm not on omneprazole) The thought of getting rid of this bacteria is really wonderful.

Thank you for posting! I will surely keep your comments in mind in the next couple of days when the treatment gets difficult!:-)
susan wrote:
Hi, I am so sorry for not posting sooner, I have been away, In answer to your questions. I took the following as I am allergic to penicillin:
I took this for 14 days
Bismuth 4 times a day
Tetrecycline 6 times a day
metronidazole 3 times a day
omeprazole once a day 20mgcf
I do not have the grams per item at hand, but I am sure if you mention to your doctor that it is the quadruple therapy they will know the exact grams. For me, I think the bismuth did the job, plesase do some research on this to see what it does to h pylori.
I have not been retested, but will do so, but trust me, I am not lying when I tell you that, my acid reflux, nausea, bloating etc is a thing of the past. I mean it has stopped 100%. When I had the bug, I used to have to watch what I ate and near enough sit up in bed my reflux was so bad. I have completey stopped the omeprazole for the acid. I NEVER have acid, so h pylori was definetely the culprit. I have had 2 sets of antibiotics for this in the past, both triple therapy, and I know within one week that they had NOT worked, as my symptoms persisted.
I must stress though, be very strict with how you take your pills, if it says no milk with them, do not drink milk, as this reduces their effectivness. I actually made myself a spreadsheet with what to eat and when etc to remind me. I will email this to anyone who wants it, please leave your email address. I hope this hels you all as I really know how horrible this bug is, and I am a bit dissapointed by doctors who really undermine this awful bug. I am even thinking of setting up a website to help people through this as the doctors don't understand what it is like unless they have suffered with it themselves.
Please remember you must be very strict with timings and everything as this is the way it worked for me. Good luck

United States

#31 Apr 26, 2011
Im so scared and lost..I too have h pylori, it cause tremendous bloating, nasea stomach ALOT, crampy feeling, problems with bowel moments, constopated and then diareah sometimes, shaky feeling, headache sometimes, gas that wont relieve most times..Now they put me on the metronidazole and the flagyl and pepto since I could not afford the 400 dollars in thw ''heli pac'', I took a few ONE TIME And had to quit it as it made me feel very depressed and blue..Im not saying it will do this to everyone but did to me..HELP!!I need an alterntive..Im tired , so tired of being sick :(

United States

#32 Apr 26, 2011
my email is [email protected] , please reply if you have alternative that works, or informtion..also please put H PYLORI at top of page so I will know to read as my inbox is all mess and hard to figure whats what..Thank you all so much.

Cambridge, MA

#33 May 25, 2011
hi Susan,

I started quadruple therapy. could you please email me what foods you ate and how to take antibiotics.

Thanks a lot


Cambridge, MA

#34 May 25, 2011
my email is [email protected]


#35 May 27, 2011
hi Susan,

not sure if you still check this page, but if you are there could please forward me the information as well as I just started with quadruple therapy. here is my email [email protected] thanks

Saint Charles, MO

#36 May 29, 2011
susan wrote:
hi, I suffered from hpylori for over 2years, I had constant acid feeling in my stomach all day, I felt nauseaus, acid reflux, bloating, it was horrible. I was on 20mg of omeprazole all this time and the symptoms persisted.
I was put on two separate courses of antibiotics, but neither worked. So in the end I did my research on american websites to see what dose was best. It turns out my doctor had under prescribed me the amount I should have been taking. I really think doctors dont' realise how bad the symptoms can get.
So in the end I told my doctor what course I wanted to take. I insisted it be a 14 day course, not a 7 day course and a quadruple course, with bismuth.
I was really strict with when I took my pills, I even made a spreadsheet to tick them off as I took them. I also took care to not drink milk or eat food before the pills that said this on the instructions as they would not be as effective.
I finished the course and started to feel better, then I just stopped my omeprazole, it took my stomach about a week to settle as you do get a sort of rebound when you stop the omeprazole.
And guess what, I no longer have ANY acid stomach, refux, nausea etc. I feel great. I have not yet been tested to see if it has gone, but I just feel normal for the first time in 2 years and after the other treatments I still had the hpylori symptoms.
It has now been nearly 3 months and no symptoms at all.
So my advice to anyone is go straight for the quadruple therapy with bismuth. Be really strict whilst taking the pills and if it says don't eat before then don't do it, so they work to the maximum. You do feel crap whilst on them, but no way near as crap as I have felt every day for the last 2 years.
If anyone has any questions, just ask. I know what you are going through.
For me, the mastic, aloe vera, etc, never worked for me, but that is just my own experience.
All the best to others who are trying to eradicate this nightmare. If I ever caught it again, I would go straight for the quadruple therapy with bismuth, without a doubt.
Hi Susan,
I too have H.Pylori and started the quadruple therapy 2 days ago. I was wondering if you were still symptom-free at this time and how long did it take before you began to feel better during the treatment regimen? Did you have heartburn/weird acidy feeling in throat with yours? Did you have a follow-up breath test? Do you still avoid certain foods? Any comments appreciated.

Thanks :)

Culver City, CA

#37 May 30, 2011
Hi SUSAN i know this post is late but can you email me about your spreadsheet at [email protected]

Put in the subject area "Susan from U.K" thanks. I am so glad your symptoms are gone. Please email SUSAN

United States

#38 Jun 9, 2011
Hi, Susuan,
I was wondering if you can email me your spreadsheet at [email protected]

I failed the triple therapy and I'm going to see the doctor soon.

many thanks.

Warner, Australia

#39 Jun 15, 2011
Hi all,

I thought I'd share my current experience. Here's a little on my background first, followed by my experience. I've numbered my paragraphs so that you can refer to them.

1. I live in Australia (I mention this as I will list the brand name of my medication)

2. I work in IT and am at the top of my profession, as such I am very analytical and will usually seek a scientific view point.

3. I cannot confirm this, but my consultant, as do I, believe that I have had H-Pylori for decades. This is likely as I spent much of my teenage years living in a developing country.

4. I do not believe home and natural remedies can eliminate H-Pylori. I believe they can sometimes relieve the symptoms, but once off, I personally believe the symptoms will return. H-Pylori is an amazing and very resistant bug.

5. My concern is not so much the very uncomfortable symptoms, but the increased risk in stomach cancer associated with H-Pylori. My consultant has made it clear that this increased risk only occurs after 40-50 years of having H-Pylri. More can be read here:


6. Please be aware that according to the H-Pylori foundation, H-Pylori is VERY common. Staggeringly so. A visual representation of the epidemiology can be seen here:


7. A few months ago, I had a Urea breathe test (that involves blowing into a bag after taking a pill) and the breathe count (counts per minutes and is the scale the amount of H-Pylori is present) returned from the pathologist as 3600. A typical positive (according to the pathologist) is 800. I *think* the scale differs from test to test, so I wouldn't use it to benchmark against your own results. A great document on how breathe counts are measured can be seen here:


8. My GP was concerned (about the high count and the Cancer thing) and was quick to prescribe me the conventional first line triple therapy course:


Namely: Nexium HP7 (an australian brand name) that consists of:

a. Antibiotic: Amoxil (amoxycillin trihydrate) x 4 capsules a day. Each capsule is 500mg

b. Antibiotic: Klacid (Clarithrmoycin) x 1 tablet a day. Each tablet is 500mg

c. Proton-pump inhibitor: Nexium (Esomeprazole) x 2 tablets a day. Each tablet is 20mg.

The medication is pretty awful. Nausea and stomach cramps and disorientation etc. Taken for 7 days.

After the course, the symptoms were gone for a week and then returned.

9. My GP recommended an Endoscopy for the H-Pylori and another condition I was suffering from (Eosinophilic Esophagitis). After a gastric biopsy, the results returned as a "moderately active" amount of H-Pylori. Difficult to compare with the first test as no breathe count was taken, but I assumed that the earlier antibiotics killed some of the bacteria. But, it was clear I now had a resistant strain. Hardly surprising considering the decades of antibiotics since I've been infected.

10. So now I am on a second-line quadruple therapy. I would like to point out that the addition of Bismuth does not mean quadruple therapy. There is a triple therapy that has Bismuth too. What makes it quadruple is the addition of a particular potent antibiotic called Furazolidone. According to Wikipedia Furazolidone is banned in the USA (?) Here in Australia, special permission had to be gained from a government agency before it was sent to me by post.

To clarify, I'm now on all of the medication in point 8 above PLUS:

a. Furozolidone antibiotic x 4 tablets a day (each 100mg)
b. De-Nol (Bismuth) x 2 tablets a day (each 350mg)

The medication in point 8 is for 7 days, the medication in point 10 an additional 3 days, totalling 10. This round makes the other seem like popping candy. Diarrhoea, covered in a rash, strong nausea, extreme tiredness. Lasts for about 3 hours after taking the medication before I can function.

I'm on day 3. I'll let you know how it goes.

Warner, Australia

#40 Jun 16, 2011
Oh, just to add. H-Pylori is not gone until another breath test/gastric biopsy is done. Unfortunately eradication of symptoms does not mean eradication of H-Pylori.

Wellington, New Zealand

#41 Jun 16, 2011
Hi Drew

Thanks so much for sharing that with us. My story is very similar to yours too. I believe I've had this for decades. I lived in Africa for years, had loads of antibiotics throughout my life and have failed a first line treatment (PPI, Amoxycillin, Clarithomycin).

I've managed to keep it under control for the last year or so using natural stuff..broccoli sprouts, mastic gum etc. but recently found out, after starting to experience the old symptoms that I still have the pylori.

I'm just about to embark on a De-Nol, Metronizadole, Tetracyclene and a PPI for 14 days.

Good luck with your treatment..I look forward to hearing your progress. Keeping fingers crossed for you!

Warner, Australia

#42 Jun 16, 2011
Thanks Smudge1. You too!

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