Diabetes Drug Tied To Heart Risks

There are 110 comments on the CBS 2 - KCAL 9 story from May 21, 2007, titled Diabetes Drug Tied To Heart Risks . In it, CBS 2 - KCAL 9 reports that:

A new analysis links the widely prescribed diabetes drug Avandia to greater risk of heart attack and possibly death.More than 6 million people worldwide have taken the GlaxoSmithKline drug since it came on the ...

Join the discussion below, or Read more at CBS 2 - KCAL 9.

Small Voice By The Still

Saint Paul, MN

#84 May 24, 2007
Considering the circumstances, I'd say at least one cuss word is allowed.

If you don't have diabetes or heart disease, thank God!
ironhead

AOL

#85 May 24, 2007
whom wrote:
How many of these doctors , which prescribe avandia and metformin have American blood in their veins?
not many
antiquerose123

Saskatoon, Canada

#86 May 24, 2007
Tenn hillbilly wrote:
<quoted text>you need to talk to your doctor...i found the leg and tired muscles was caused by my diet,,,also how low is your blood suger.is it to low..also you will find drinking tea.instead of coffee will help..the sweating will go away if you eat right///keep your diet below 1600 cal.for at least 2 weeks..talk to your doctor and get the proper diet..
THANKS TENN HILLBILLY...COULD BE, THE LOWEST IT HAS GOTTEN DOWN TO IS 3.7AND I FELT LIKE I WAS GOING TO FAINT. SOMEONESAID TO ME THAT WHEN I SWEAT LOTS, IT IS MY BODY TELLING ME TO EAT...AND ONE DAY THEY SAID TO ME "WATCH, ONCE YOU EAT YOU MOST LIKELY STOP SWEATING"...AND IT DID. MY MUSCLES FEEL LIKE THEY ARE WEAK, AND LIKE THEY ARE PULLED. I STILL WORK, BUT THAT REALLY BURNS ME OUT....
Small Voice By The Still

Saint Paul, MN

#87 May 24, 2007
Lay off that whiskey and let that cockaigne be!
Jeff

Newport, TN

#88 May 25, 2007
frances wrote:
my daughter took this drug and she died of heart trouble two years ago.
This is the most uneducated group of comments I have heard. Avandia is safe and the benefit certainly outweights the risk. 65% of diabetics die of cardiovascular disease regardeless of medication. Avandia keeps patient alive longer.
no name

United States

#89 May 25, 2007
Jeff wrote:
<quoted text>
This is the most uneducated group of comments I have heard. Avandia is safe and the benefit certainly outweights the risk. 65% of diabetics die of cardiovascular disease regardeless of medication. Avandia keeps patient alive longer.
In this case I don't believe that. Maybe you work for the pharmaceutical company? I know of a story of a nurse who gave 10 mg of a drug to her patient because she read the doctors order incorrectly. The doctors order read 1.0 and the person died. NO MEDICATION CANNOT BE ALL THAT HEALTHY FOR A PERSON!
I CAN TAKE A WHOLE CUP OF BROCCOLI WITHOUT THE SLIGHTEST DAMAGE.
wjb

United States

#90 May 25, 2007
Alex wrote:
<quoted text>
Yes, heart murmurs are a possible side effect of Avandia. Are you pre-disposed to heart failure?
Alex
PharmD Candidate
I am not sure, I haven't had any problems until the last six months or so when I noticed rhythm problems. I will be paying a visit to the cardiologist next week.
no name

United States

#91 May 25, 2007
Small Voice By The Still wrote:
Considering the circumstances, I'd say at least one cuss word is allowed.
If you don't have diabetes or heart disease, thank God!
Cuss words are unacceptable to many people under any circumstance. They are very unprofessional and they are a risk to a person's eternal life. A person must ask themselves if this is a risk they really want to take.
Alex

Smyrna, GA

#92 May 25, 2007
Jeff wrote:
<quoted text>
This is the most uneducated group of comments I have heard. Avandia is safe and the benefit certainly outweights the risk. 65% of diabetics die of cardiovascular disease regardeless of medication. Avandia keeps patient alive longer.
I wish that what Jeff were saying is true, but it's not. Yes, diabetics are more succeptible to cardiovascular problems, but I don't know where he got his statistics because the study conducted to show that Avanda attributed to a 64% increase in deaths due to CV problems, was conducted side-by-side with diabetics on other normal "secretagogues" (insulin enhancers) as the control group, meaning that the spiked increase is in fact due to the drug, not just the underlying condition of heart problems due to diabetes. I just want people to be aware that this drug has the propensity to be dangerous and that there are safer alternatives out there that WILL work.

Alex
PharmD Student
vegejuicer

United States

#93 May 25, 2007
Alex wrote:
<quoted text>
I wish that what Jeff were saying is true, but it's not. Yes, diabetics are more succeptible to cardiovascular problems, but I don't know where he got his statistics because the study conducted to show that Avanda attributed to a 64% increase in deaths due to CV problems, was conducted side-by-side with diabetics on other normal "secretagogues" (insulin enhancers) as the control group, meaning that the spiked increase is in fact due to the drug, not just the underlying condition of heart problems due to diabetes. I just want people to be aware that this drug has the propensity to be dangerous and that there are safer alternatives out there that WILL work.
Alex
PharmD Student

Pills are not healthy they frequently cause death from various problems. In the past I thought damage was done mostly to kidneys and liver because these 2 organs detoxify the body and are damaged in the process of the detoxification. I knew however damage to other body systems could occur such as blood cell damage brain and nerve cell damage. Until this news came out I was mostly unaware they caused heart attacks.
A good healthy lifestyle could do much to prevent diabetes and other diseases in the first place. Sometimes it can also cure diseases. I know of people who have cured themselves with healthy lifestyles.
Phenomenal

Brookline, MA

#94 May 28, 2007
Try alternative or natural medicine.
Small Voice By The Still

Saint Paul, MN

#95 May 29, 2007
no name wrote:
<quoted text>
Cuss words are unacceptable to many people under any circumstance. They are very unprofessional and they are a risk to a person's eternal life. A person must ask themselves if this is a risk they really want to take.
You gotta accentuate the positive.

Watch what you eat and drink. Drink lots of filtered water. Plain oatmeal for breakfast. Use Sweet & Low.

Pray. Trust God.
John

Savannah, GA

#96 May 30, 2007
Your diabetes caused your heart attack, not the medicine.
Frederica Harris wrote:
I have been on Avandia since it was first put on the market. In 2005, I developed a blod clot in my right coronary artery, causing me to have a heart attack. Could Avandia be to blame? Why is it that these studies are always after the fact? They warn people about buying drugs from Canada and Mexico because they may not be safe. What about the drugs purchased in the United States approved by the FDA? The truth is, that we cannot trust our government to make sure that the drugs being used in this country are safe. So what happens now? They pull it off the market and start a class action lawsuit? That really helps the ones who have died from heart attacks after taking Avandia.
Look At It This Way

Saint Paul, MN

#97 May 30, 2007
Small Voice By The Still wrote:
<quoted text>
You gotta accentuate the positive.
Watch what you eat and drink. Drink lots of filtered water. Plain oatmeal for breakfast. Use Sweet & Low.
Pray. Trust God.
Absolutely!
CSlaughter

United States

#100 Jun 6, 2007
My 43 year old stepfather had never had any significant health problems until 5 years ago, he was diagnosed with type 2 diabetes. He has been on Advandia for 5 years now, I was terrified of these new reports. Late last year he was having chest pains and shortness of breath and after a cath. he was diagnosed with blockages and has had 7 stents placed over 5 different cath procedures. He has been diagnosed woth severe coronary artery disease. He has NO small vessels in his heart that are functioning anymore. We have suffered everyday with the thought of losing him to this and wondered how did this come about so suddenly and to such a degree, I guess we know now. These greedy ass pharmecutical companies should be shut down! I have already lost my dad to a heart attack but the thought of losing the one who raised me because of a drug is outrageous and sickening!!!!!!!!!!
Stanley - KY

Louisville, KY

#101 Jun 6, 2007
I have taken Avandia for about three years and it has controlled my blood sugar. However, I have felt for the last two years that I have had a weaker heart. I have recently experienced a racing heart and wondering if this may have been caused by Avandia. Also, my mother has been on the drug for three years and had a heart attack about two years ago. Last year she had Congestive Heart Failure twice within a few months. She is 81 and has been a diabetic for a long time.
Craig

South Windsor, CT

#102 Jun 7, 2007
Small Voice By The Still wrote:
<quoted text>
You gotta accentuate the positive.
Watch what you eat and drink. Drink lots of filtered water. Plain oatmeal for breakfast. Use Sweet & Low.
Pray. Trust God.
HAHAH Sweet and low? The stuff that kills lab rats or gives them Cancer if they get fed 1000 times the recomended daily limit?
I am Diabetic and I use Splenda. There has been no nown links to death using this artificial sweetener yet. I said , YET.
I called my Dr. about Avandia today and his nurse has informed me that the drug is fine but if I felt the need , that I could stop taking it if I wanted.. Sure I could stop taking Glucotrol and Glucophage as well, and then what happens to my blood sugar?I also take Vytorin,a cholesterol lowering drug,but even that has a disclamer that it will not prevent a risk of a heart attack.Seems ironic that lowering your cholesterol wont prevent heart attack,but I guess for legal reasons they have to make that claim. Who knows if I am going to stop taking Avandia,they come out with a new study evey day.Yesterday they came out with a study saying Folic Acid (another med. my dr. is pushing)is bad for your liver but it still has heart strengthening properties.. So who knows what to believe, ha maybe the Folic Acid will cancel out the Advandia side effects and will only efect my Liver... GEESE it's always something, All those cholesterol meds have a chance of messing up your liver, thats why you need to have blood tests if you are on them.
Remember Baycol for cholesterol?(before they came out with the wonder drug Liptor) I was on that for 3 weeks and suffered a constant what felt like I had run a marathon in my legs.. That lactic acid kind of BURN when you run for a long time. Told the Dr. and he said , Na it can't be the pills.. A few days later I called him again and told him I did not feel like this before I went on Baycol ,so I am OFF these pills!Went off the pills and the BURNING stopped. A week later they pulled Baycol off the market because it had killed too many people!
It's all just a money game to these drug companies.They meet a quota for people who die takin the pills and then they just take the pill off the market. Like Rezulin.. Remember that GEM of a pill for diabetics??
They all just treat us like car accidents.If an intersection has enough accidents,then they put up a stoplight... Just hope you are not a statistic on the way to havin them put up that stop light.
Good Luck

C
Emma

Guilin, China

#103 Jun 14, 2007
life was like a box of choclate, you never know what you are going to get,
KathyZ

Kalispell, MT

#105 Jun 15, 2007
jonmulliniks wrote:
WELL I HAVE BEEN TAKING AVANDIA FOR YEARS, I NEVER HAD A PROBLEM WITH COLESTROL, BUT ABOUT A YEAR AGO MY DOCTOR TOLD ME THAT MY COLESTROL IS A MESS, AND i WONDER IF THE ADVANDIA HAS CAUSED THAT AND THAT i NEED TO GET OFF THE DRUG...DO YOU HAVE AN OPINION?
I took Avandia for 9 months while simultaneously eating carefully (low-fat diet), exercising, and losing 64 pounds. At the same time my cholesterol level has continued to rise in spite of a lifestyle that should have lowered it instead. I have suspected the Avandia, but cannot find any research that would link it. Has anybody else?
Horsewoman

Kalispell, MT

#106 Jun 15, 2007
I took Avandia for 8 months and even though I was eating a low-fat diet and lost 64 pounds during that time, my cholesterol levels have increased steadily, defying reason. I cannot find research that points to Avandia for my rising cholesterol levels, but suspect it. Anybody know any such research?

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