Diabetes Drug Tied To Heart Risks

A new analysis links the widely prescribed diabetes drug Avandia to greater risk of heart attack and possibly death.More than 6 million people worldwide have taken the GlaxoSmithKline drug since it came on the ... Full Story
JT Barrie

Springfield, OR

#23 May 22, 2007
We have the same problems with Avandia that we have with Meth. The government requires little actual evidence to take action. With Avandia there are clinical trials for approval for each drug for a specific purpose. These are done over a short period of time and only prove that these drugs work better than placebos. Bad side effects happen only after chronic use - so when I see the term "rare but serious side effects", I chuckle "they're only rare because the drug is so new".
Meth on the other hand was banned with no studies whatsoever. The cause of the ban was a small group of people who decided to deliberately misuse the product for deliberate impairment[get high]. What happened after criminal prohibition is that criminals took over production and distribution and Meth disappeared only to be replaced by Crystal Meth - a variant that was rarely used by the original abusers.
Despite the shortage of studies, getting drugs approved in this country is ridiculously difficult - compared to other countries. However, once they're approved they are hyped to no end, convincing many desperate people to coerce their physicians into putting them on the drug.
Maybe we should seriously consider privatizing the research and let the free market decide approval. We should ban ads for these drugs until more comprehensive studies of long-term effects are completed. People should not be denied new treatments by the government because of the FDA. Drug companies should be denied the early surge of profits from development - until all the bugs are worked out.
BTW, the risk of dependency has nothing to do with the drug and everything to do with the condition the drug treats. If your condition is mostly irreversible, all drugs used in treatment have huge risks of dependency. And are patients really addicted to using the drug - or are they addicted to living their lives free of pain or discomfort?
As for drugs like Meth and Cocaine: put them all in a "drug house" for recreational use, require disclosure [as if that really deters hard core users], and let the market decide. I'd rather have society deal with the thousands of people committing mayhem because they ARE using - than the tens of thousands who commit mayhem because they are NOT using and need money to pay for overpriced drugs.
chalee KY

Auburn Hills, MI

#25 May 22, 2007
I took Avandia for 4 or 5 year now.Lately my hart is been pain all time. And I have to go to do EKG,but they said nothing wrong with my hart. What I have to do now?
Ellie in UK

London, UK

#26 May 22, 2007
I could hardly believe my eyes when I saw Belle Frye's comment.

I've been glugging tonic water to keep leg cramps at bay and was wondering why I was getting sore veins and blue splotches on my legs.

Seems that Beta Blockers increased my chances of getting Diabetes by 50%- now Avandia is posing a similar risk for heart disease. I'm binning those pills and off to see the Doctor.
Yvonne O Connor

Auburn Hills, MI

#27 May 22, 2007
3 years ago I was placed on Avandia with the following side effects: Horrific constipation and weight gain. I was on this medication for a few months and took myself off. I had reactions after going off and the weight was nearly impossible to lose.
Peter7l

Wilmington, DE

#28 May 22, 2007
Folks,
People who are diabetic usually and have always died from heart failure sometimes after they become blind and sometimes before. This was the truth before Avandia just as it is now. So stop being so hysterical because it is the disease that causes the problems not the drug. Without Avandia patients would be progressing to insulin much sooner. Once you are diagnosed with type II diabetes there is no going back because the damage is irreversible. The only thing you can do is slow the process down with drugs. It is much harder to control your blood sugar with insulin compared to Avandia. Poor control of blood sugar is what causes all the damage to your body i.e. eyes and cardiovascular system. Avandia is 100% proven to substantially delay the progression of diabetes from type II to the very nasty type I.
Peter7l

Wilmington, DE

#29 May 22, 2007
chalee KY wrote:
I took Avandia for 4 or 5 year now.Lately my hart is been pain all time. And I have to go to do EKG,but they said nothing wrong with my hart. What I have to do now?
Try taking Prilosec OTC for a couple of weeks to see if your heart pains go away. You can buy it without a prescription now at your drug store. This drug controls the amount of stomach acid. Excess stomach acid can cause pain which appears to be near the heart. Let us know the outcome.
Louise

United States

#30 May 22, 2007
All meds have side effects...even aspirin. Any drug you take should be well thought out and researched. Just because an MD prescribes it, does not mean it's safe...and drug companies are clearly motivated by profits, so refuse to be a lab rat for them. Demand years of FDA testing and studies and do your own research. All medications should be a last resort---use only when absotlutely necessary to prolong life. Take responsibility for lifestyle changes FIRST, and you may never need a pill that may kill you later on. I am diabetic and suffer from severe pain due to spinal cord compression from degenerative disc disease. I exercise daily (90 minutes or more) to control my blood sugar and my pain. It isn't easy---but had I taken meds that were prescribed 15 years ago, I wouldn't be posting this now. Take back your control---say NO to the drug companies.
Gloria

Rushmore, MN

#31 May 22, 2007
I've been trying to get my doctor to take me off Avandia because I can't afford it
I have insurance that pays 60% and I still have to pay $165.00 so when the drug companies is making this much money I doubt if they will easly be persuaded to take it off the market
jonmulliniks

Meridian, MS

#32 May 22, 2007
I have been taking this drug for years twice a day, I have stopped, yesterday, will the body renew the damage? and what now??? I have always said stay away from doctors if you can, or they will kill you with these drugs...they only know what the PH. Salesman tells them, in most cases...I believe that you should use your own judgement after consultanting with doctor, they are doing their best to make all the money that they can, believe me, and you and I will be just another statistic...maranatha!!! my blog : Lil Pearley in your search window or the address: http://jonmulliniks.blogster.com
Lois Davis

United States

#33 May 22, 2007
Why are we buying these drugs from forign countries
Read behind the headline

UK

#34 May 22, 2007
read the study and what is behind it.....this is a poor study and would be laughed at by scientists...choose your outcome and you will get a result.Worth looking at who sponsors the writer and seeing what drugs they sell for diabetes!
Angry at stupid people

United States

#35 May 22, 2007
For all of you people complaining about your loved ones you lost...first, I'm sorry for your loss. Second, Avandia probably gave you a few extra years with your loved one.
Healthnut

United States

#36 May 22, 2007
They should heve commercials saying,'good diet & exercise, the anti-drug.' If people didn't develop type 2 diabetes in the first place this wouldn't happen.

High blood sugar over a long period of time can cause lost limbs, kidney failure, blindness, and yes, death. Avandia had probaly prolonged those lives of the people who died.
Nicole

Houston, TX

#37 May 22, 2007
...Never trust the FDA.....we should be looking into holistic measures to combact disease.....never trust the FDA....go to there website you will not be able to take half the durgs over the counter.......never trust the FDA...
jim from michigan

United States

#38 May 22, 2007
Peter7l wrote:
Folks,
People who are diabetic usually and have always died from heart failure sometimes after they become blind and sometimes before. This was the truth before Avandia just as it is now. So stop being so hysterical because it is the disease that causes the problems not the drug. Without Avandia patients would be progressing to insulin much sooner. Once you are diagnosed with type II diabetes there is no going back because the damage is irreversible. The only thing you can do is slow the process down with drugs. It is much harder to control your blood sugar with insulin compared to Avandia. Poor control of blood sugar is what causes all the damage to your body i.e. eyes and cardiovascular system. Avandia is 100% proven to substantially delay the progression of diabetes from type II to the very nasty type I.
This is typical, this is what is wrong with our country, it takes years of unhealthy eating, lack of excerise, and doing vises in excesses, for most, this is the reason behind the significant increase disease in the recent years, then when people are affected they want instant resolution, e.g drugs, there are NATURAL Remedies to control And with some aliments even cures.very few people put forth the effort and work to do their own research, i do not have diabetes BUT i do have a very rare and very painful affliction which the doctors know very little about, i've had this for almost 20 years, 12 years ago they (the doctors) told me i was wheelchair bound unless i started a certain drug regiment, it wasn't a cure and would just slow progression and the side effects were scary at best, i started looking for natural remedies and i'm still walking today, in fact better than i was 12 years ago, i go to our family doctor once a year for a physical, just for my own peace of mind, my bloodpressure is perfect, cloesterol is perfect, as well as my sugar indexes, besides my condition which has impaired my mobility some i'm still in perfect heath otherwise, point being is there are Alot of natural remedies. do you know it illegal for anyone,even a doctor.... to tell you about a cure if it isn't a approved fda drug, for instance.. scurvy completely cureable, but they can't patent the cure because it's natually occuring and easily attainable. I hope people wake up and see that the government and drug companies are tied together at the hips, the good people of this country need to get off there ass and do a little research and work for themselves instead of believing everything a doctor, drug company, or the government tells them is true.
Man in the White Hat

Ojai, CA

#39 May 22, 2007
All part of the New World Order.
juliday

Auburn Hills, MI

#40 May 22, 2007
....so which is worse...taking it, or not taking it???
Read writing on the wall

Houston, TX

#41 May 22, 2007
very interesting to to fda.com ....hit recalls.....you will be suprized....
Furious and victimized

Etobicoke, Canada

#42 May 22, 2007
I cannot believe this garbage, I'm furious and disgusted! Even worse, some of the ignorant responces from some of you, saying people should be thankful to the drug companies for offering a drug that extends your life. Until you've been in a similar situation and experienced a loss or side effects keep you arrogant heartless comments to yourself. These drug companies are vulutures who make a living from the illnesses of people who trust them.
I'm a young healthy male 31 yrs old, I've always been active and regularly exercise since I was 16 yrs old. I'm not overweight, I don't eat fast food, I don't drink or smoke, don't do drugs...and what I deserve this! Perhaps I should be thankful?
I don't have type II diabetes. I was put on this drug as a volunteer patient because I suffer from chronic psoriasis. They told me this drug was safe by my doctor. He told me the side effects were minimal and only affected old people which is a lie. I was very skeptical about doing this trial research from the beginning in early 2003. The drug trial lasted for 1 yr. Thank God I did not experience any side effects, although I'm terrified to think about the long term damage that may have been done. Sure were all fine now, but what about 5, 10, 20 yrs down the line.
This taught me a very valuable lesson, never trust you doctors full advice. Seek other doctors opinions and investigate ALL other options before commiting to new medications.
All these drug company criminals will do what they do best. They will bribe the right people, hire the best lawyers to sweep all this under the corrupt government heirarchy and again get away with killing sick, innocent trusting people.
Severe criminal punishment should be used as an example against these devious pharmacieutical companies.
kathy from ontario

Canada

#43 May 22, 2007
I've been on 2 avandia plus 5 metforms a day I am other wise healthy but I get racing heart beat that lasts for hours. this has been going on for a year

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