Illness course impacts suicide risk in bipolar and depressive disorder
Differing illness course, rather than the illness itself, is the greatest determinant of the differential risk of suicide attempts between patients with bipolar disorder and those with major depressive disorder , study findings indicate.
Join the discussion below, or Read more at Medical News.
Saint Petersburg, FL
#1 Mar 23, 2014
The selling of bipolar disorder stresses that the disorder takes a fearsome toll of suicides. And indeed the controversy surrounding the provocation of suicide by antidepressants has been recast by some as a consequence of mistaken diagnosis. If the treating physician had only realized the patient was bipolar, they would not have mistakenly prescribed an antidepressant. Because of the suicide risk traditionally linked to patients with bipolar disorders who needed hospitalisation, most psychiatrists would find it difficult to leave any person with a case of bipolar disorder unmedicated. Yet, the best available evidence shows that unmedicated patients with bipolar disorder do not have a higher risk of suicide.
Storosum and colleagues analyzed all placebo-controlled, double-blind, randomized trials of mood stabilizers for the prevention of manic/depressive episode that were part of a registration dossier submitted to the regulatory authority of the Netherlands, the Medicines Evaluation Board, between 1997 and 2003 . They found four such prophylaxis trials. They compared suicide risk in patients on placebo compared with patients on active medication. Two suicides (493/100,000 person- years of exposure) and eight suicide attempts (1,969/100,000 person-years of exposure) occurred in the group given an active drug (943 patients), but no suicides and two suicide attempts (1,467/100,000 person-years of exposure) occurred in the placebo group (418 patients). Based on these absolute numbers from these four trials, I have calculated (see Figure S1 showing calculation, and see Figure 2) that active agents are most likely to be associated with a 2.22 times greater risk of suicidal acts than placebo (95% CI 0.5, 10.00).
Read more http://www.plosmedicine.org/article/info%3Ado...
The psychiatric pharmaceutical industry does not want the public to know that the best available evidence shows that unmedicated patients with bipolar disorder do not have a higher risk of suicide.
Add your comments below
|Viagra May Help Women (Jul '08)||23 hr||pillenapotheke||11|
|Facts about bipolar disorder||Mon||MaryWh||2|
|Few kids receiving mental health care - Zeni (Jul '08)||May 17||many went 2 Acton||11|
|botcho cream for buttocks/hip enlargment (Sep '12)||May 17||sista||18|
|Antidepressants not as effective as previously ...||May 16||HumanSpirit||1|
|Depressed? It could be adult ADHD||May 16||HumanSpirit||1|
|Study reveals why some depressed patients have ...||May 14||space ace||2|
Find what you want!
Search Depression Forum Now
Copyright © 2016 Topix LLC