Abilify plus an antidepressant for mo...

Abilify plus an antidepressant for mood disorders

There are 256 comments on the Channels.netscape.com story from Nov 25, 2005, titled Abilify plus an antidepressant for mood disorders. In it, Channels.netscape.com reports that:

The atypical antipsychotic drug Abilify appears to enhance the response to antidepressants in patients with treatment-resistant major depression, research suggests.

Join the discussion below, or Read more at Channels.netscape.com.

Kim- Swartz Creek- MI

Southfield, MI

#23 Nov 16, 2006
I have been on Zoloft,Wellbutrin SR, and Abilify for over a year now. I am stable emotionally, but I have been having trouble with 25-30# weight gain. I am athletic and try to eat well and not alot of calories, no more than 1800cal/24day. I want to change to a different antipsychotic to see if I can lose this weight. I hate buying bigger clothes and I don't feel I look very healthy either. anyone else having problems with weight gain??
mojo

United States

#24 Nov 16, 2006
hey Kim from swartz creek, we're neighbors sort of..........my isp location is wrong.
are you partof the zyprexa law suit?
Abilify is just as bad if not worse than Zyprexa for weight gain, I took abilify as well the only way I was able to loose my weight was to quit taking the abilify and apply some serious dedication to the American Diabetes Association Diet.
I limited my carbs to 45 grams per meal then I found the Dr Bernstein Diet which goes much further and I applied some of those principles to the diet as well and further reduced my carb intake to about 50 grams per day, and lost 20 pounds in my first month, 13 pounds in my second month and by the third month my weight loss dwindled to about 5 to 7 pounds per month.
get checked for diabetes, abilify is known to contribuate to diabetes and weight gain is also a huge factor in diabetes.
Be careful
be very careful
CSW

AOL

#25 Nov 16, 2006
Hello. My husband has been on Lithium for 23 years and sadly, he has lost almost 60% of his kidney function due to this medication.Lithium has always worked fairly well for his bipolar disorder but he has to get off of it or will end up on kidney dialysis. After much discussion, he is going to try Abilify; although it is with much trepidation. Tegretol was another choice offered but felt that there was a better chance of success with Abilify. Our main concern is the risk of tardive dyskinesia. Any one hear of any cases of this occurring with Abilify...we understand it is not as likely as with the older antipsychotics but there still is a chance. Thank you!
worried mom

St Louis, MO

#26 Nov 17, 2006
My daughter is eight years old.Since she was about two I have delt with mood swings, agitation, crying, and an occastional super happy day. I have tried everything, went to classes, spent more time with her, have been stern but fair etc. In kindergaten I learned my daughter had dyslexia, and that contributed to her emotional highs and lows since dyslexia affects the ability to follow more then one direction at a time, hearing sounds properly and the ability to learn how to read. It was exstreamy hard on me, and her father was never around to help, so at all fell me. I wouldn;t trade being her mother but god I needed to rest. I became agitated and worn out. Then my husband and I got divorced two years ago. This compounded my daughters problems ten fold. She was never happy, complained all the time, we even where seeing a counselor twice a week for a while. I tried evrything not to turn to any medication, but she developed stomache troubles that where getting worse, she was prescribed a medication to lessen the acid in her stomache so she wouldn't get ulcers from all the anxiety, but her mood was so sad. I was watching my baby, my eight year old daughter slip into what I saw as an unrecoverable depression. I was loosing her. Her therapist saw it too, and sent us to a psycatrist. after a long exstensive evaluation, and the fact that my grand mother, mother and older sister all suffered from bi-polar and my sister with violent psycotic episodes the doctor suggested Abilify in a small dose. I hesitated because I worried about side effects. But I heard my eight year old admit she wished she were dead, and I couldn't take the chance of that ever happening. I reluctently took the prescription for my daughter, thinking the benefits out weighed the side effects.

My daughter was started out on 2.5mg for two weeks, then moved up to 5mg. It has been almost a month in a half. She is a whole new child. She is doing well in school, the teachers have said she has had a phonomoinal turn around and is less agitated and more focused. She seems to relate to the other students better, and now can take several directions at a time. At home she is better with her sister and expresses herself in a more suitable way. We now can talk. She now feel more confidant and seems general happier.

After reading all the side effects and other things I am scared. But I also see this has been the only thing ever to make a difference, and is said to have the least amount of side effects.

Does anyone else have a take on this?
Schizophrenia

Wolverhampton, UK

#27 Nov 17, 2006
Just to add about Abilify. After i was diagnosed the psyc doc put me on onlazapine/zyprexa 5mg but it caused me weigt gain of 1stone in 6 months.

Then he changed it to Abilify Only 5mg a day of and within 4 days i had to go back to zyprexa as Abilify was not safe neither right for me. Baisicly in those four days it caused my symptoms to be worse like the first weeks when the illness started.

Apart from loosing sleep it speeded everything up my mind including my heart rate. I was in a state of parania, confusion, axiety & agitation i felt like my head was going to explode and at night when i closed my eyes didn't know what was goin on especial with my heart. Some of these symptoms i didn't have befor.

Any ways i had a bad experience to Abilify i'd think due to it was meant for the treatment of my condition.

Josh

Mount Tremper, NY

#28 Nov 17, 2006
Sunshine wrote:
My husband is on a combination of Abilify and Wellbutrin, and the positive changes in him are absolutely phenomenal! I wish we'd have gotten that done sooner!
"voodoo economics is sorcery and ronnie reagan a warlock"

profound political statement heed the call ^

im a young guy, 20 y.o., always been labelled as a bright and intelligent invididual by teachers,doctors alike
disagnosed as bipolar at around 11-13 y.o.
numerous symtpoms are intensifying in these last couple to few years leading me to isolate
potential schizophrenia as chaotic and disorganized thoughts intensify
as im still young, id like to go to college..pursue academic discourses and in all likeliehood become a teacher
im considering seeing a doctor and suggesting the same combo as mentioned above (abilify and wellbutrin)
ive been on wellbutrin before for a short while, it alleviated depressive symptoms and have me a degree of focus and concentration ive not had in some time
if available..id like to speak with you further about your husband, his condition and progress made
anyone else available to give recommendations, advice, solice, kindness, suggestions or share personal stories similiar in nature to my own..please contact me
TCanick

Sterling, VA

#29 Nov 22, 2006
Sunshine wrote:
My husband is on a combination of Abilify and Wellbutrin, and the positive changes in him are absolutely phenomenal! I wish we'd have gotten that done sooner!
I am also on this combo and it appears to be working reasonably well. I am presently weening myself from Effexor, which both worked and didn't.
Mackula

Roebling, NJ

#30 Dec 21, 2006
TCanick wrote:
<quoted text>
I am also on this combo and it appears to be working reasonably well. I am presently weening myself from Effexor, which both worked and didn't.
I'm also taking 5mg Abilify, just started 150mg Wellbutrin and weening off of 12.5mg Paxil. So far my moods have stablizied and have been feeling rather good. I still feel very tired all of the time even though I sleep well. There has been a weight gain though that I think is because of the Abilify.
Rumple Stiltskin

Poughkeepsie, NY

#31 Dec 22, 2006
I am a thorozine victim - survivor, 1978, at age 10. Thirty years later my parents still refuse to admit what they did to me was torture - lobotomy.
anon

AOL

#32 Dec 24, 2006
No more meds 4 me wrote:
I was in a double blind study for abilify about 5yrs ago I found out since then that it seems to be o.k. but in my opinion it's too early in long term effects studies for it to be considered safe for children.Some people nowadays are quick to have their kids diagnosed or are quick to think they're predisposed to have something biologically inherited from their parents.Try to cut back on meds and get creative on passing on social tools or coping skills so to speak.My parents thought meds were the answer and I spent my adolescence doing the thorozine shuffle leaving me to contemplate why I had to take pills and my peers didn't.Kids talk at school you know.Don't pass off your lack of parenting skills by just saying your kid(s) is manic or has learning disabilities or is bi-polar.For pete's sake their brains haven't even matured yet.Kids will be kids.Don't put them on drugs because they don't think the way you want them to.
THANK YOU. TRUTH IS THESE KIDS WILL MORE THAN LIKELY ABUSE DRUGS WHEN THEY ARE OLDER...FOR SELF ESTEEM REASONS.
Alexs Mom

Pleasanton, CA

#33 Dec 27, 2006
My son is 6 1/2 and was just put on Abilify a week ago. He is diagnosed with PDD-NOS (on the autism spectrum) with this he has horrible mood swings, violant outbursts and does not sleep well. Its been a week and we already can see a differance. He takes 2mg a day and he just smiles more, is more at peace and pays more attention. We are hoping this is a huge key to the puzzle at school.
Yes I too was very worried about the side effect but they are a low risk and his quality of life is important as well.
worried mom wrote:
My daughter is eight years old.Since she was about two I have delt with mood swings, agitation, crying, and an occastional super happy day. I have tried everything, went to classes, spent more time with her, have been stern but fair etc. In kindergaten I learned my daughter had dyslexia, and that contributed to her emotional highs and lows since dyslexia affects the ability to follow more then one direction at a time, hearing sounds properly and the ability to learn how to read. It was exstreamy hard on me, and her father was never around to help, so at all fell me. I wouldn;t trade being her mother but god I needed to rest. I became agitated and worn out. Then my husband and I got divorced two years ago. This compounded my daughters problems ten fold. She was never happy, complained all the time, we even where seeing a counselor twice a week for a while. I tried evrything not to turn to any medication, but she developed stomache troubles that where getting worse, she was prescribed a medication to lessen the acid in her stomache so she wouldn't get ulcers from all the anxiety, but her mood was so sad. I was watching my baby, my eight year old daughter slip into what I saw as an unrecoverable depression. I was loosing her. Her therapist saw it too, and sent us to a psycatrist. after a long exstensive evaluation, and the fact that my grand mother, mother and older sister all suffered from bi-polar and my sister with violent psycotic episodes the doctor suggested Abilify in a small dose. I hesitated because I worried about side effects. But I heard my eight year old admit she wished she were dead, and I couldn't take the chance of that ever happening. I reluctently took the prescription for my daughter, thinking the benefits out weighed the side effects.
My daughter was started out on 2.5mg for two weeks, then moved up to 5mg. It has been almost a month in a half. She is a whole new child. She is doing well in school, the teachers have said she has had a phonomoinal turn around and is less agitated and more focused. She seems to relate to the other students better, and now can take several directions at a time. At home she is better with her sister and expresses herself in a more suitable way. We now can talk. She now feel more confidant and seems general happier.
After reading all the side effects and other things I am scared. But I also see this has been the only thing ever to make a difference, and is said to have the least amount of side effects.
Does anyone else have a take on this?
Alexs Mom

Rockville, MN

#34 Dec 27, 2006
My son is 6 1/2 and just started taking Abilify a week ago. He is on Adderal XR, Prozac, and Trazadone (though benadryl now works better for him I just swithed). Yes, abilify already has seemed to help him in just a week! I hope it continues but I understand your concern as a parent. There are risks, my son is isolated at school, has outbursts for no reason and lashes out at people, I have to think of his well being and quality of life. I feel this is the right choice though it is gut renching, difficult and make me question what I'm doing to my child though when I see him smile, make friends, and play with others I feel like I'm doing the right thing.
Kathy wrote:
<quoted text>I am trying to decide whether to puy my daughter on abilify. Her doctor has prescribed it but I am afraid of the side effects. She is only 18 and is taking Adhd medication and prozac and trazadone. It seems like overkill. How old are you and do the side effects go away after awhile?
Steve

AOL

#35 Dec 27, 2006
It's a good medication. I take 20 mgs of it. That is the only medication that I am prescribed. I sleep a lot on it though. I also gained weight.
BSK

Muscatine, IA

#36 Dec 29, 2006
Kim -
My son has been on many of the drugs you mention, but it was not until he started Ambilify that his weight gain exploded. He doesn't appear to have less energy, but if he doesn't get plenty of rest he gets frustrated and angered easily. I don't know of any alternatives to Ambility but I am considering taking him off this drug to see if it helps his rage (the wieght reduction and reduced risk of diabedes would be a secondary win).
BSK

Muscatine, IA

#37 Dec 29, 2006
My son (now 8) was put on medications for severe obsesive behaviors and general anxiety disorder. This later matured into more frequent angry outbursts (almost rage filled). His first year of school he was sick almost every day (vomiting). We didn't realize it at first, but some of his sickness was self induced (in the stalls of the rest room or when his head was down, with finger in mouth). He also would get sick without self induction as witnessed by the teachers in class. On weekends - magically - NO SICKNESS. He also has his happy highs and manic lows as you've described. The doctors have danced around many diagnoses, but we are seeing a new Dr. in March to get his thoroughly tested (blood, psyc, hearing, etc). Ambilify has cause him to gain a lot of weight. We went through a period of bliss for a couple months, but now (no med change) he is having extreme moments of unmerited rage. He directs it at every figure of authority even after most repond with consistant love and compasion to him.(I fought for shared custody of my son and his younger brother and sister a year ago - the divorce confounded my sons issues, but I don't see it as core)- I welcome more sharing of history as I am desperate to do right by my son and am also worried about the Antipsychotic - Ambility on his young developing mind ([email protected])
BSK

Muscatine, IA

#38 Dec 29, 2006
worried mom wrote:
My daughter is eight years old...
please see above reply from BSK
Anonymous

Omaha, NE

#39 Dec 29, 2006
In response to the posts above. I have been on Abilify and Zyprexa. That was a while ago. I don't remember the affects they had on my mood but Zyprexa caused severe weight gain. Anyway, I am not a doctor, but my doctor put me on a drug called GEODON at least a year ago. No weight gain since and about twenty pounds lost through diet and exercise. I used to take a capsule of geodon at night to sedate and one in the morning, but was sluggish after morning pill so I switched to two at night. I don't know if GEODON is alright for children but could be worth asking your doctor about. Geodon helps me sleep at night, was almost hyper before at night with racing thoughts, it may help with rage. But again, I'm not a doctor, don't take my advice without consulting a doctor, it is just that my doctor said that GEODON had the same effects of abilify and zyprexa with little to no side effects.
undecided

Oregon City, OR

#40 Dec 31, 2006
my son has been diagnosed with bipolar by two different child psychiatrists..but two other psychologists think that the behavior is either adhd or nonverbal learning disorder.. we have been given abilify which is concerning to me..this is the first day that he is on it.. i don't see any improvement..but i don't see any horrible side effects yet..any suggestions..does anyone know how dangerous it is to give a bipolar/adhd child a stimulant like ritalin or concerta..that seems to me to be a far safer drug
worried mom wrote:
My daughter is eight years old.Since she was about two I have delt with mood swings, agitation, crying, and an occastional super happy day. I have tried everything, went to classes, spent more time with her, have been stern but fair etc. In kindergaten I learned my daughter had dyslexia, and that contributed to her emotional highs and lows since dyslexia affects the ability to follow more then one direction at a time, hearing sounds properly and the ability to learn how to read. It was exstreamy hard on me, and her father was never around to help, so at all fell me. I wouldn;t trade being her mother but god I needed to rest. I became agitated and worn out. Then my husband and I got divorced two years ago. This compounded my daughters problems ten fold. She was never happy, complained all the time, we even where seeing a counselor twice a week for a while. I tried evrything not to turn to any medication, but she developed stomache troubles that where getting worse, she was prescribed a medication to lessen the acid in her stomache so she wouldn't get ulcers from all the anxiety, but her mood was so sad. I was watching my baby, my eight year old daughter slip into what I saw as an unrecoverable depression. I was loosing her. Her therapist saw it too, and sent us to a psycatrist. after a long exstensive evaluation, and the fact that my grand mother, mother and older sister all suffered from bi-polar and my sister with violent psycotic episodes the doctor suggested Abilify in a small dose. I hesitated because I worried about side effects. But I heard my eight year old admit she wished she were dead, and I couldn't take the chance of that ever happening. I reluctently took the prescription for my daughter, thinking the benefits out weighed the side effects.
My daughter was started out on 2.5mg for two weeks, then moved up to 5mg. It has been almost a month in a half. She is a whole new child. She is doing well in school, the teachers have said she has had a phonomoinal turn around and is less agitated and more focused. She seems to relate to the other students better, and now can take several directions at a time. At home she is better with her sister and expresses herself in a more suitable way. We now can talk. She now feel more confidant and seems general happier.
After reading all the side effects and other things I am scared. But I also see this has been the only thing ever to make a difference, and is said to have the least amount of side effects.
Does anyone else have a take on this?
Alice Jones

United States

#41 Dec 31, 2006
Alexs Mom wrote:
My son is 6 1/2 and just started taking Abilify a week ago. He is on Adderal XR, Prozac, and Trazadone (though benadryl now works better for him I just swithed). Yes, abilify already has seemed to help him in just a week! I hope it continues but I understand your concern as a parent. There are risks, my son is isolated at school, has outbursts for no reason and lashes out at people, I have to think of his well being and quality of life. I feel this is the right choice though it is gut renching, difficult and make me question what I'm doing to my child though when I see him smile, make friends, and play with others I feel like I'm doing the right thing.
<quoted text>
THE ONLY atypical approved for children is Resperdal for children with autism. We NEVER used to give all these drug cocktails to children. Did it ever occur that ADHD drugs can kick a child into "bipolar" (my children got bipolar at age twenty. It is congenital in my family. My son went on Zyprexa, after years on lithium, a proven natural salt, and died within two years.) I wouldn't do it. I have an acquaintance whwo refused to drug her child, spent many hours finding the right natural/organic foods and behavior management at home and at school a nd her child is doing well. I would never subject my child to this danger, knowing what I now know and having a permanently broken heart. Beware.
Zoompad

Coventry, UK

#42 Jan 2, 2007
Alice Jones wrote:
<quoted text>THE ONLY atypical approved for children is Resperdal for children with autism. We NEVER used to give all these drug cocktails to children. Did it ever occur that ADHD drugs can kick a child into "bipolar" (my children got bipolar at age twenty. It is congenital in my family. My son went on Zyprexa, after years on lithium, a proven natural salt, and died within two years.) I wouldn't do it. I have an acquaintance whwo refused to drug her child, spent many hours finding the right natural/organic foods and behavior management at home and at school a nd her child is doing well. I would never subject my child to this danger, knowing what I now know and having a permanently broken heart. Beware.
It's good to see someone speaking out against drugging children. My son is also autistic, and I will never allow him to be put on drugs, never.

There are alternative ways, much better ways, of helping children with autism. Unfortunatly, our societies do not seem to have the patience to help these children (although lots of parents, especially mothers, break themselves in half to help their children)

I think these children are treated like shitscum by the education system in the uk, and it makes me feel really angry. I will never drug my child just because some "expert" tries to co-erce me, for cheapness sake, to make my child more placid and easy to control. I am sorry about what happened to your son, Alice.

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