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Kay

Palm Desert, CA

#1 Jul 28, 2006
If you are told Zetia does not give you muscle pain like statins, don't believe it. My doctor had me try Lovastatin, which gave me muscle pains in legs and arms after 15 days. He then gave me Pravastatin and within 10 to 12 days I had muscle pain in legs and arms plus joint pain. In both cases after I stopped taking these drugs, the pain was gone within 36 to 48 hours. Three days ago he put me on Zetia and told me that it would NOT cause the muscle pains like statins. On the second day, I started to feel joint pain and on the third day, my leg and arm muscles were killing me. I left a message with my doctor's nurse but have not heard back from them yet. I am taking myself off of the Zetia and I will NOT take any more prescription cholesterol lowering drugs. My cholesterol will just have to remain hi.
Minny

United States

#2 Jan 14, 2007
Kay wrote:
If you are told Zetia does not give you muscle pain like statins, don't believe it. My doctor had me try Lovastatin, which gave me muscle pains in legs and arms after 15 days. He then gave me Pravastatin and within 10 to 12 days I had muscle pain in legs and arms plus joint pain. In both cases after I stopped taking these drugs, the pain was gone within 36 to 48 hours. Three days ago he put me on Zetia and told me that it would NOT cause the muscle pains like statins. On the second day, I started to feel joint pain and on the third day, my leg and arm muscles were killing me. I left a message with my doctor's nurse but have not heard back from them yet. I am taking myself off of the Zetia and I will NOT take any more prescription cholesterol lowering drugs. My cholesterol will just have to remain hi.
Your cholesterol doesn't have to remain high. Just get off all animal products, eat a diet high in vegetables, whole grains, fruits and nuts and seeds. Mine went down 60 points in a few weeks. It can be done. My mother died at 68 from heart problems/high cholesterol and so it runs in my family. Mine is now at 141 and I am 48 years old. Go to Dr. John McDougall's website and plug in cholesterol and read all of the great changes people have made.
rebecca

Washington, DC

#3 Apr 13, 2007
i took zetia for one month, stopped after developing unusual muscle and joint pain esp. knees hips. i stopped taking zetia three months ago and my symptoms have not changed. i am in constant pain. will they ever go away? i'm hopeful!! BE WARNED!!!!!!!!!!
Gem524

Akron, OH

#4 Jun 17, 2007
I have a cholesterol of 254. My bad cholesterol is 190.
My doctor prescribed Zetia 10mgs. I have not started taking it yet. After reading all the reactions people have had on this, I am scared to try it..I decided to cut this small pill in half, because I am supersensitive to meds.I did this in the past with Zocor, and my cholesterol still went way down..had to get off Zocor, cause of the leg and stomach pains..
Doesn't anyone have good to say about this Zetia pill?
terri

Englewood, CO

#5 Sep 20, 2007
I was on zetia and simvastatin for 1 year and been having muscle aches in the upper part of my back, lower back, knees, arms stiffen, toss and turn at bedtime, shoulders.....I stopped taking both as of yesterday and my leg pain feels a bit better, but will give it more time and see if all goes away. In the meantime, i'm going to look for an alternative natural medicine to take. Anyone know of any good ones taht really work?
donh

Redwood City, CA

#6 Oct 4, 2007
I have had similar experiences with statins and Zetia over the past couple of years. Starting with Lipitor, after only a few weeks I began waking up multiple times each night with tingling so severe in my hands / arms that I would have to get up and walk around. I then switched to Crestor, which seemed to be symptom free for a few months, but soon I was having new muscle, tendon, and joint pain. After 2 Crestor dosage reductions followed by augmentation with Zetia, muscle pains and joint stiffness recurred, so I recently stopped cholesterol meds completely. Now, all of my pain & stiffness is gone, and am convinced these drugs are not for me! I exercise quite a bit and have heard that side effects like this are more common with active lifestyles. Has anyone else noticed this?
Dave

Maple Grove, MN

#7 Nov 2, 2007
I have had muscle and joint pain while taking statins and have went through the list from Lipitor to Zocor to Pravachol to Zetia and now Crestor.

Zetia had the worst side effects and in less than two weeks I stopped taking it. I have CHF and my heart function went down by 10% in that time period.
Kidney function was also affected.

The joint pain was in both my feet and hands. I was unable to grip a golf club and was walking on my heels to avoid putting any pressure on the toe joints.

Two weeks after stopping the medication I was pain free.

There must be another way.
Alfred

San Diego, CA

#8 Nov 12, 2007
Have been on various statins and went to Zetia. I was aware that I could have muscle pain. When ever working in the yard I would be overly sore in by joints. So I thought. Worked vary hard in my yard moving a lotof dirt into my one ton truck and shoveling it off at the dump. That night my muscles in the back of my head, collar area and buttocks were extremely sore. Could not sleep. It has been that way for at least 4 to 5 weeks. Stopped taking the Zetia and the pain has lessened somewhat. I can not find anything on the Internet about correcting the muscle, joint pain. It is difficult to sit on the toilet, sleep , get up off of a chair etc. Will this pain ever stop, should I start working out the muscles daily or take some thype of other medication.?
frank

Fremont, CA

#9 Jun 20, 2008
I have been on 10 Mg Zetia since 2007, and it seems to help, for I can reach a 143 reading.
It took a while to get to adjust to this medication. The shoulder muscle pains started, at first, but with weekly adjustments, the pain lessened and went away.
I am seeking a lab reading below a 100.
Marie Theron

South Africa

#10 Jun 21, 2008
ALFRED: It is very important tot take sufficient CoEnzymeQ10 while on any cholesterol medication. You must test for myopathy (muscle damage).
Alfred wrote:
Have been on various statins and went to Zetia. I was aware that I could have muscle pain. When ever working in the yard I would be overly sore in by joints. So I thought. Worked vary hard in my yard moving a lotof dirt into my one ton truck and shoveling it off at the dump. That night my muscles in the back of my head, collar area and buttocks were extremely sore. Could not sleep. It has been that way for at least 4 to 5 weeks. Stopped taking the Zetia and the pain has lessened somewhat. I can not find anything on the Internet about correcting the muscle, joint pain. It is difficult to sit on the toilet, sleep , get up off of a chair etc. Will this pain ever stop, should I start working out the muscles daily or take some thype of other medication.?
WandaM

Merrick, NY

#12 Jul 15, 2008
Nancy

Saint Paul, MN

#13 Aug 2, 2008
OMG it's so nice to find this site!

Although it makes me nervous to stop the Zetia, I must. It tricked me, because I have been on it for a year or two, and I thought any side effects would have already happened.

The last several weeks, my thighs started getting so sore that I can't walk normally. I can't climb stairs without pulling myself up with railings and sliding against the wall! I can't lift my legs. I toss and turn at night, and my hips & buttocks hurt. I thought it may be coincidental since I started a different job a few months ago that is more physical. I know it is the Zetia. I had tried three statins in the past and had different type of muscle aches.

This is scarey. I'm going to have to find a way to lower my cholesterol naturally.

Pepper

AOL

#14 Aug 16, 2008
my husband was put on zetia three years ago. he is not the kind to complain, so i had to notice what was going on. he is having memory problems, itching, sweating, and shoulder pain. can we just stop it ourselves. thank you
Ant

Los Angeles, CA

#15 Nov 23, 2008
I had a series of problems with a statin - muscle pains, tendonitis, injuries that did not respond easily to Physical Therapy, I had an X-ray and a cortisone injection did work. I did not relate any of this to the statin until reading a blog on the internet. Nor did I relate having coke colored urine that smelt of yesterdays beef wrapper to the drug. Nor did I know until months after I had point blank refused to take any more statins that azole antifungals have a dangerous interaction with statins. Although I have been told that topical usage of the azole antifungal does not count, I am not completely convinced, as I had used the antifungal for such a long period of time.
I tried Zetia a few months ago and quit the drug after 5 weeks as I was getting the problems again. First legs cramps. I am about to start physical therapy again for my left elbow, although it feels like there is also something wrong with my left shoulder and my right finger. To be fair to Zetia, perhaps if I had never used the anti-fungal nor the statin , then all would be fine.
Donh suggests that the cholesterol medication has the worst impact on those with an active lifestyle. I have also read this. On a busy day I walk as much as 9 miles and my work involves using my whole body. The last ten days have been really tough!
Richard O

Merrick, NY

#16 Nov 25, 2008
christian

Warrensburg, MO

#17 Feb 28, 2010
rebecca wrote:
i took zetia for one month, stopped after developing unusual muscle and joint pain esp. knees hips. i stopped taking zetia three months ago and my symptoms have not changed. i am in constant pain. will they ever go away? i'm hopeful!! BE WARNED!!!!!!!!!!
I've taken Zetia on three different occasions over the past 6 months and experienced the same hip pain you're discribing. It's turning me into an old man each time. The first time I stopped, the pain went away. Not so the second time, thus making me believe it may be something else. Last week I started it again, and the pain is worst than ever, keeping me from sleeping through the night. On my first experience, my pain went away shortly after starting a round of prednisone. I started another round this morning and hope that will take away the pain once again. I'll post again in about a week, to let you know if that worked. My recommendation to others is not to use Zetia if you experienced muscle or joint pain when you tried the statin drugs. I am now taking Krill Oil to reduce my cholesterol, and I'm very excited about the possibilities, no only for cholesterol, but for joint pain as well.
P.S. I will also be adding Niaspan back into my arsenal. It provides many of the same benefits as the statin drugs, but I've never experienced muscle/joint pain with it until the doctor increased my dosage to 2000 mg per day. Niaspan (niasin) comes with flushing, but works best if taken at night. You'll get a flush that will wake you up every once in a while, but most of the time, you sleep right through them if taken with aspirin or Aleve.
christian

Warrensburg, MO

#18 Mar 8, 2010
rebecca wrote:
i took zetia for one month, stopped after developing unusual muscle and joint pain esp. knees hips. i stopped taking zetia three months ago and my symptoms have not changed. i am in constant pain. will they ever go away? i'm hopeful!! BE WARNED!!!!!!!!!!
I promised to post again to let you know how the Prednisone worked to take the pain out of my hip. I've been sitting at the computer for some time now and just got up with no pain in the hip. It took longer than I expected, and my dosage is not over yet. I started out with 60mg a day for two days, 50mg for two days, 40mg for two days, and just went to 30mg this morning. The prednisone is working, you just have to get off it.

Let me also recommend another natural substance to you to help cholesterol and arthritis. Antarctic Krill Oil. I purchased it from VitaCost.com . Best prices, excellent quality. I have some arthritis in my right index finger I have had problems with for years. After a week on Krill Oil, it's gone. It supposedly reduces bad cholesterol by 36% and increases good by 43% vs. about 4% with fish oil. Give it a try. It certainly what put you in a wheel chair the way Zetia was moving me toward.

I noticed this site had not been posted on for a couple years. I sure hope someone gets this information and can use it. I'm certainly glad I found it. Thanks...
Stuart Anstis

Slovakia

#19 Jun 6, 2010
Statins have few possible side effects, for example Lipitor - most famous statin has side effects for one full page :) Check this - http://www.lipisite.com/lipitor-side-effects....
Jessica

Kaneohe, HI

#20 Jul 9, 2010
I have been on various statis to lower my cholesterol, all with the same side effects of severe muscle pain in my legs and thighs. My physician switched me to Zetia a few years ago and I did not experience the muscle pain for the first year or two. In the last year I started having some muscle soreness that I attributed to doing a lot of activity and being on my feet all day. In the last few months the pain in my legs is so bad that I had difficulty standing after sitting at the computer for an hour or lying down for for a little while. Like other people, I felt like I was going to be crippled. I reported this to my doctor and she suggested I stop taking it for a month to see if the muscle pain goes away. I am very reluctant to try anything else.
Leg Pain - Rhabdomyolysis

United States

#21 Jun 26, 2011
If you experience joint pain, pain in the calves of your legs or other muscle pain you are developing Rhabdomyolysis - toxic poisoning to your muscle tissue due to the intake of Statins. It is very dangerous in the latter stages and fatal due to Kidney failure, release of excess potassium from the muscle into the bloodstream which can cause a fatal heart rhythm and excess bleeding due to changes in the blood's ability to form a clot.

I took one Zocor and the next day I could not walk. Two years later, I let an alternate doctor talk me into taking Zetia. After two weeks I am now unable to walk due to the muscles in my calves being damages. A visit to the ER convinced me. They told me not to take Statins. Some of us are just plain allergic to it and cannot tolerate the smallest amount in our bodies.

If you have that kind of pain after being prescribed Statin and the doctor does not give you a blood test to see if you have Ryabdomyolysis you should change doctors or go to the ER where they will give you the blood test. And, stop taking the Statin - this can't hurt you but Ryadomyolysis can be fatal.

Don't risk your life because a doctor says Statin is not harmful to you. Without the blood test, he hasn't the faintest idea if it is harmful to you or maybe he does.

Remember that pharmaceuticals and doctors have have lowered the cholesterol standard by 30 points so that they can prescribe more Statins and make more money than they already do. Heaven knows they make enough money already.

In closing, be careful with Statins and make sure your symptoms are not due to Statin intake.

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