Estrogen-Testosterone Combo Could Up Risk

Full story: The Associated Press

Older women who take hormone pills that combine estrogen and testosterone more than double their risk of breast cancer, according to a study of more than 70,000 nurses.
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1 - 20 of 29 Comments Last updated Sep 23, 2013
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Karen -Nurse Practitioner

Fairbanks, AK

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#1
Jul 25, 2006
 
I believe the benefit of this medication for most women outweighs the risk provided the person taking the medication is aware of the possibility and the percentages of that risk. Crossing the street in a traffic area has risk and although I don't know the percentage I would guess it would be higher than the possibility of getting breast cancer due to this medication. Quality of life has to be weighed and I believe it would tip the scales largely in favor of the benefit derived from this medicine. Ultimately, it comes down to personal choice but needs to be done with non judgemental information.
Susan Hochstetter

Denver, CO

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#2
Jul 26, 2006
 
If I had the choice to do it over again, I would certainly not take Estrogen and Testosterone no matter what the symptoms of menopause were. After being on the combination and having breast cancer, the benefit would never outweigh the risk. It is very easy to say that you feel it outweighs the risk if you have never had breast cancer. I believe that you would change your mind.
amc

Orange City, FL

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#3
Jul 27, 2006
 
help, I have NO sex drive, haven't for atleast 10 years. I know I have hormonal problems, hemorraging every 21 days. WEnt to gyno, tested me for estrogen and progesterin but never mentioned testestorne? Why? Why can't I be told the information? So I can say, yes... give me the hormones, monitor me and let me have a chance at passionate feelings again.. I am sick of crying and being moody every three weeks!
Pamela

O Fallon, MO

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#4
Aug 24, 2006
 
I am taking a HRT Femhert and was wondering if anyone out there has taken this drug and what complications you had. So far it has taken away my hot flashes (power surges) and I can sleep at night, don't have the mood swings. I'm 49 and I have fibrosist disease and am concerned about having more of a risk of getting breast cancer with taking HRT.
Jane

United States

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#5
Sep 16, 2006
 
Yikes. Where was I when this latest report came out? I still agree with what one of the writers said, the number of women who got breast cancer was still statistically very small. I'm wondering if I should try once more to wean myself from these very complicated pills. My symptoms are pretty horrendous and if they return as they usually do, I think I'll go back on. but I hate feeling I'm taking this chance.
Thanks for your input, all of you.
Ellen

Phoenix, AZ

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#6
Oct 28, 2006
 

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Following complete hysterectomy and non-functional adrenals, estrogen therapy alone was useless. Estratest has restored to normal: thinning skin, stopped bone loss (fosamax alone or with estrogen ineffective), restored my sunny assertive personality, muscle mass back to normal, energy level returned. Antidepressants make me feel awful. If the gov takes this option from me, I will scour the earth to find it again. Please, let me be the person to decide how much risk is too much.
TONI

Austin, TX

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#7
Jun 21, 2007
 

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I have NO desire for sex, have not since I started periomenopause. Can anyone tell me if the estrogen and testosterone combo has helped them regain a normal sexual desire?
TONI

Austin, TX

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#8
Jun 21, 2007
 

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I have NO sexual desire, have not since perimenopause five years ago. Can anyone tell me if they have taken the estrogen/testosterone combo? AND, has it helped?
Bonnie

Stockton, CA

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#9
Jul 3, 2007
 

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DOES EVERY ONE NO WHERE ESTROGEN COMES FROM?A PREGNUT MARES PEE. THEY HAVE TO KILL HER AND THE BABY SHE IS CARRING.LOOK IT UP .
darlene

Grayling, MI

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#10
Jul 4, 2007
 
I had the choice to do it over again, I would certainly not take Estrogen and Testosterone no matter what the symptoms of menopause were. After being on the combination and having breast cancer, the benefit would never outweigh the risk. My doc said it did not cause breast cancer but it escalated it to where I would have lived long enough to die from something else like natural causes instead.
Judy

Kingsland, GA

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#11
Aug 1, 2007
 

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I am a long term user of estratest. Had a total hysterectory at 32, have been on estrogen or estrotest for 35 years since then. Feel great except when I stop, or recently, when a pharmacy gave me generic, insisting they were equivalent. Within a month I was whiney, weak, a total drip. Back on the real thing, I feel great again, can run my business, help lots of people and enjoy my husband and friends. I dislike taking pills and am concerned about breast cancer, but for me, life is just way too gloomy without estratest.
Carolyn Cook

Stoughton, MA

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#12
Aug 9, 2007
 
I took Estratest for 9 years before I developed breast cancer. I am convinced that my cancer was due to a high dose of estrogen and progesterone in addition to Estratest. I felt great, looked great....life was good, however, I would not have taken HRT if I had been aware of the risk for developing breast cancer. The risk is just too great. It has been almost 4 years since I was diagnosed....the hot flashes are only bearable but I am alive and feel good.
Patti Stiles in Atlanta

Atlanta, GA

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#13
Jun 4, 2008
 

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I took Estratest only 3 years before developing breast cancer (diagnosed 1/08). My doctor knew I was at high risk for breast cancer (my mother has had two different types), yet he prescribed it anyway. I am convinced that this drug gave me cancer. Please, please get off this hormone, especially if you are in a high risk category.
danka

Corinth, NY

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#14
May 7, 2009
 
Bonnie wrote:
DOES EVERY ONE NO WHERE ESTROGEN COMES FROM?A PREGNUT MARES PEE. THEY HAVE TO KILL HER AND THE BABY SHE IS CARRING.LOOK IT UP .
excuse me...NO!!! WHERE??? What's a pregnut? Idiot
Joanna

United States

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#15
Jun 1, 2009
 
Judy wrote:
I am a long term user of estratest. Had a total hysterectory at 32, have been on estrogen or estrotest for 35 years since then. Feel great except when I stop, or recently, when a pharmacy gave me generic, insisting they were equivalent. Within a month I was whiney, weak, a total drip. Back on the real thing, I feel great again, can run my business, help lots of people and enjoy my husband and friends. I dislike taking pills and am concerned about breast cancer, but for me, life is just way too gloomy without estratest.
My experience is identical to yours, except I've been taking Estratest only 12 years now, following a complete hysterectomy. Today I learned that Solvay announced on 3/10/09 that it had stopped making Estratest and Estratest HS. Since every time I've had an interruption or taken the generic I felt like I'd been run over by a truck, I am really at a loss how I'm going to retain any quality of life. Do you have any suggestions?
Brenda

AOL

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#17
Jul 14, 2009
 
I've been taking Estratest for 4 yrs and also recently found out that Solvay has stopped manufacturing. I actually ran out last week & my GYN was on vacation. The unbearable hot flashes have started already. I spoke to my GYN today & she perscribed an estrogen replacement only. I've tried them in the past but it didn't help the hot flashes. But it's not only the hot flashes, it's what happens to me mentally. Feels like I have PMS EVERYDAY! I may look into an herbal alerternative. Does anyone have any suggestions??
Joanna wrote:
<quoted text> My experience is identical to yours, except I've been taking Estratest only 12 years now, following a complete hysterectomy. Today I learned that Solvay announced on 3/10/09 that it had stopped making Estratest and Estratest HS. Since every time I've had an interruption or taken the generic I felt like I'd been run over by a truck, I am really at a loss how I'm going to retain any quality of life. Do you have any suggestions?
andrew langham

UK

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#18
Jul 26, 2009
 
testosterone is an essential part of cell transcription note when testosterone becomes adultarated by chemicals rogue genes' HIV etc then mis-transcription occurrs causes disease alzhimers, fibroids, cancers, aids hiv and many many other medical conditions such as diabetes; andrewlangham@yahoo.co.uk
Tammy

AOL

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#19
Nov 5, 2009
 
Ive been on estratest hs for 5yrs now with no problems at all . my dr put me on femhrt. omg its not working the terrible headaches and the roaring in the ears. here we go again on the rollercoaster to hell n back. this is sad because it worked. i was happy not hot flashes, no problems. now we all have to find a new one that works. wish insurance paid for bio identical hormones. life would be so much easier. limited incomes hurt too. cause most of the combipatches or pills are not covered. pharmacutical companies are making out like fat rats while the rest of us suffer.
alex

New York, NY

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#20
Nov 5, 2009
 
Same problem here, I need my estratest and I was given the generic, don't know what to do, don't trust the generic it does not feel the same. I have been taking it for 10 years without any problems. I don't know what to do, any opinions?
Lou

O Fallon, MO

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#21
Nov 21, 2009
 
I took estratest for almost 10 years before it was pulled from the market. Sex drive gone. Having hot flashes, night sweats. MISERABLE. Tried generic a few times, but caused acne and generally irritated skin.

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