Wyeth - Prempro / Premarin: settlement

Wyeth - Prempro / Premarin: settlement

There are 54 comments on the PharmaGossip story from Jul 20, 2008, titled Wyeth - Prempro / Premarin: settlement. In it, PharmaGossip reports that:

Back stories here. Wyeth has agreed to settle a Nevada case in which two women claimed that its hormone-replacement drugs Prempro and Premarin caused their breast cancer.

Join the discussion below, or Read more at PharmaGossip.

chanelglass

Alameda, CA

#21 Oct 24, 2008
Believe me I know all about the risks involved. I had a biopsy on
the wrong breast in 2006, this was
all way before I began taking Prempro. I have fibrocystic breasts.
I realize many Women believe there
is a strong correlation between HRT
and breast cancer.

I do not plan on staying on Prempro
for years! Today I feel good, and
for this day I feel much gratitude.
Gail Perry

Pinellas Park, FL

#22 Oct 24, 2008
It does ease symptoms, there's no doubt about that.

Chanel, I didn't criticize *your* muscle mass. And, I've explained why I think it's a bad idea. I think it's just messing with Mother Nature in a very fundamental way. We could also end menstrual cramps, which I found far more distressing than the symptoms of menopause, by the constant administration of birth control pills, but it's never been tried because no one thinks that, in that case, using hormones to alleviate symptoms is a good idea.

I see HRT in the same way. And believe me, I know about menopaus symptoms. On an AI, my menopause symptoms have been tripled. I did not know a person could have that many hot flashes in a day or perspire that much. The slightest raise in temperature ...

Sorry. I assumed that when you gained mass you gained weight.

I would just like women to think very carefully about HRT. It clearly has been tied to increase breast cancer. It also increases the risk of ovarian cancer, blood clots, heart attack and stroke. Obviously we aren't having a tidal wave of disastrous side effects but the risks are real, which brings me back to the fact that HRT "treat" a normal stage of life.

That's my bias: that menopause is no more a medical condition requiring medication than puberty is.
chanelglass

Alameda, CA

#23 Oct 24, 2008
You raise some interesting thoughts to ponder. I felt at one point in this whole ovaries die thing not so much hot flashes,but my anxiety attacks would come on out of the blue, and I was losing weight. My OBGYN said that some Women can lose weight.

Prempro was offered to me by my physician. I was reluctant to take this medication, then when I started taking Prempro, I felt energetic, and limber. I have quit
taking Prempro many times. One day
I will just decide to quit. I do
cherish my energy and general feeling of well being. I understand
your point of view.
Gail Perry

Pinellas Park, FL

#24 Oct 25, 2008
Well, I'm glad it helped you, but I would like women to know that I felt energetic without it.

Your OB/GYN is right. Most women gain wait in menopause, not lose it.

Honestly I think whether you "feel well" is partly about how you perceive menopause. My mother was a woman who seemed to have a crystal ball hidden in her closet somewhere. She pointed out in the late fifties that Florida shouldn't have planted eucalalyptus trees (I spelled that wrong) because they weren't native to FL and would make problems. We had just moved to Florida, and no one was thinking about those things then. She was concerned about the state of the environment and what we were doing it back then.

And when she and a friend entered menopause, her friend took the new estrogen drugs (now known to cause uterine cancer in some people) and she didn't.

Her friend did get uterine cancer (she survived, thank goodness). My mother had had breast cancer at 38, but the doctors were going to let her take it anyway.

That's part of my point. Just because something's been approved doesn't mean it's unlikely to cause problems. In this case, even though HRT has been around a while, they have only recently tied it to some forms of breast cancer.

Believe me, I know about wanting to feel good and be free of (in particular) the hot flashes and perspiration, but it is just a symptom. I urge people to be cautious.

One thing that has helped me (and as I say, I have hot flashes on steroids) is something called "cooling scarves." They go around your neck and they contain little beads that absorb water. When I'm having a "hot" day I wear two -- one around my forehead and one around my neck. And, I soak them in ice water. They really, really help me.
Gail Perry

Pinellas Park, FL

#25 Oct 25, 2008
I'm not trying to tell anyone else what to do, but looking for something else I just came across this, from March 2008:

"New results from the Women's Health Initiative (WHI) confirm that the health risks of long-term use of combination (estrogen plus progestin) hormone therapy in healthy, postmenopausal women persist even a few years after stopping the drugs and clearly outweigh the benefits. Researchers report that about three years after women stopped taking combination hormone therapy, many of the health effects of hormones such as increased risk of heart disease are diminished, but overall risks, including risks of stroke, blood clots, and cancer, remain high. "

http://public.nhlbi.nih.gov/newsroom/home/Get...
chanelglass

Alameda, CA

#26 Oct 25, 2008
Hormone replacement can improve life quality. I have read so many
conflicting so-called Health Initiatives. I know how I feel
since beginning this medication.

Some Women choose this medication
to help them get through this very
difficult, and confusing period of
transition.

We are all fortunate that we are
able to choose, or decline this
medication.
Gail Perry

Pinellas Park, FL

#27 Oct 25, 2008
Yes, quality of life, really, really counts. But somewhere one of my posts -- I must have failed to send it.

I pointed out that I had at least as much discomfort from menstrual cramps. Birth control pills could be used to eliminate periods, but they aren't. That was a real quality of life for me too.

As I said, not trying to tell anyone else what to do, just putting the other side out there. Only the individual woman can decide for herself.
chanelglass

Alameda, CA

#28 Oct 25, 2008
Women who take Hormone replacement therapy to treat menopausal symptoms do not have higher than usual risk of heart attack. My Dad died when he was only 46yrs. he had a condition rhuematic fever. I will always be aware of my heart health. I do have plenty of energy without taking hormone replacement.
chanelglass

Alameda, CA

#29 Oct 25, 2008
I will end this session by saying that Hormone replacement will always be a controversial subject.
Women have passion in their convictions, thats what makes for a very interesting exchange of ideas.
Gail Perry

Pinellas Park, FL

#30 Oct 25, 2008
I don't think it will always be controversial. I think they'll keep working on it and improving it, and I think one day the potential downside will really be much better. I am optimistic. They're still improving birth control pills, after all.
chanelglass

Alameda, CA

#31 Oct 25, 2008
I think Hormone replacement is still, and will always have some element of controversy.
chanelglass

Alameda, CA

#32 Oct 25, 2008
Mabey in the not too distant future pharmaceutical companies will distribute something that Women will be able to tolerate more than what is being offered.
Gail Perry

Pinellas Park, FL

#33 Oct 25, 2008
I think they'll get there.
chanelglass

Alameda, CA

#34 Oct 25, 2008
I will continue my medication(quite expensive by the way)
Gail Perry

Pinellas Park, FL

#35 Oct 25, 2008
Chanel I'm sure you are doing what is right for you.
chanelglass

Alameda, CA

#36 Oct 26, 2008
(maybe) not mabey I sure slaughtered that spelling!
Cheryl H

AOL

#37 Nov 26, 2008
chanelglass wrote:
Like I have stated on this forum previously I had a biopsy on my right breast. I have dense,fibrocystic breasts,this is all way before I began taking prempro. It was not cancer, and I can understand you are angry. thirteen years is a long time. Iam currently off prempro, and I feel terrible! In the end it all comes down to freedom of choice. By the way all of the possible side effects are explained in the Patient Prescription Information.
You are no doubt being paid by Wyeth to make comments on this forum.
You have no idea what you are talking about.
chanelglass

Alameda, CA

#38 Nov 27, 2008
Paid by Wyeth? what a angry person you seem to be. I hope you can understand the concept that Women experiencing this phase in their life will, and can choose their own path!
chanelglass

Alameda, CA

#39 Nov 27, 2008
Education, and freedom to choose short term hormone replacement is a very personal, and individual choice. Wyeth did not pay me for that comment.
Cheryl H

AOL

#40 Nov 28, 2008
If I am angry - it is a righteous anger.
Where is your compassion for all the people on this post who have gone through years of suffering because they just simply "didn't know
better". Many of us trusted our Drs. and in my
case my next door neighbor was a Dr. who came over to visit me and picked up the phone and ordered prempro for me.- I have suffered now
for over 5 years.
Just because you are opinionated in peoples rights
doesn't give you the right to judge everyone by your standards and make unkind, certainly unhelpful remarks and use this site to take up the case for Wyeth who has made billions of dollars off of a drug that has killed and injured
many innocent women.
I will not reply any further on this site - other than to say I am sorry you get your "jollies" this way.
Looking back at all these comments you have made-there is a serious lack of compassion on your part.

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