Molecular marker for the diagnosis o...

Molecular marker for the diagnosis of fibroadenoma

Posted in the Breast Cancer Forum


Madison, WI

#1 Sep 25, 2012
US patent issued on Sept. 11, 2012 – Described the use of constitutively active mutants of the prolactin receptor (PRLR) for the diagnosis or prognosis of patients with fibroadenoma, multiple fibroadenomas and hypermastia. In mutants, the Ile residue at position 76 or at position 146 of the mature form of PRLR has been substituted by another amino acid residue. Molecular analysis of these receptor mutants can be used for evaluating the risk of fibroadenoma evolving to multiple fibroadenomas.
Source: [Patent%20News]

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