Continuous Nebulized Albuterol Versus...

Continuous Nebulized Albuterol Versus Nebulized Albuterol and I...

There are 28 comments on the Fire Rescue Magazine story from Nov 7, 2006, titled Continuous Nebulized Albuterol Versus Nebulized Albuterol and I.... In it, Fire Rescue Magazine reports that:

Salo D, Tuel M, Lavery R, et al: "A randomized, clinical trial comparing the efficacy of continuous nebulized albuterol versus continuous nebulized albuterol plus ipratropium bromide for the treatment of acute ...

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KATY RIGGS

AOL

#1 Feb 25, 2007
I HAVE BEEN USING DUONEB FOR A NUMBER OF YEARS. IT WORKS QUICKER THAN AN INHALER WHICH I USE ALSO.
KATY RIGGS

AOL

#2 Feb 25, 2007
I HAVE BEEN USING DUONEB FOR A NUMBER OF YEARS. IT WORKES QUICKER THAN AN INHALER WHICK I USE ALSO.
smile

United States

#3 May 28, 2007
when instruct to use a continous nebulizer treatment which is better to use, albuteral or duoneb
Gina

Waltham, MA

#4 Jun 4, 2007
Inhaled Albuterol is just as good and safer than Duoneb. Hospitals sometimes give Duoneb in nebulized form and alternate with albuterol. But, there is no real major advantage to using duoneb, which introduces another med into your system.
Dr L

Waltham, MA

#5 Jun 4, 2007
Duoneb contains ipratropium, which is an anticholinergic substance. I advise all my patients to use Albuterol nebulization unless there is a good reason for switching to the more costly and more prone to side-effects "Duoneb". Obviously, as "laypeople" you do not fully comprehend the implications of additional medications into your system. As a learned and trained Pulmonary Specialist with credentials from Tufts Medical and Harvard, with 17 years practice at a well known Boston Hospital as well as private practice - I should know far better than random patients writing very subjective and non-scientific views. You people should listen more to your Pulmonary doctor and less to each other if you wish to maintain good health!!
Dr L

Waltham, MA

#6 Jun 4, 2007
KATY RIGGS wrote:
I HAVE BEEN USING DUONEB FOR A NUMBER OF YEARS. IT WORKS QUICKER THAN AN INHALER WHICH
I USE ALSO.
You are foolish!!
Dr L

Waltham, MA

#7 Jun 4, 2007
smile wrote:
when instruct to use a continous nebulizer treatment which is better to use, albuteral or duoneb
It depends on your intrisic leukocite pulmonary index - something that requires a PHD Function Test in a hospital setting (ask your doctor).In general, albuterol is very adequate.
Dr L

Waltham, MA

#8 Jun 4, 2007
Gina wrote:
Inhaled Albuterol is just as good and safer than Duoneb. Hospitals sometimes give Duoneb in nebulized form and alternate with albuterol. But, there is no real major advantage to using duoneb, which introduces another med into your system.
Good for you Gina. You are exactly right!!!

Since: Mar 07

San Francisco, CA

#9 Jun 12, 2007
WARRICK CFC ALBUTEROL INHALERS NOW AVAILABLE!

1. GO TO OUR PETITION AND FIND THE CONTACT INFORMATION FOR GILLESPIES PHARMACY- and remind yourself what it feels like to breathe freely again.

2. While you are there, SIGN THE PETITION TO SAVE CFC ALBUTEROL INHALERS, and MOST IMPORTANTLY, FILE A COMPLAINT BY TELEPHONE WITH THE FDA AGAINST THE NEW HFA ALBUTEROL INHALERS (phone number in HUGE RED NUMBERS- IF you have a medical complaint).

3. TELL THEM YOU WANT YOUR NAME PLACED ON THE LIST (YES, they ARE collecting names) OF PEOPLE WHO WANT TO SAVE CFC ALBUTEROL INHALERS!

ACT NOW! DO NOT WAIT!

GO HERE NOW:

http://tinyurl.com/3bul5u

You never know. We may get lucky, despite everything you've heard.

BUT EVERYONE MUST FILE COMPLAINTS (IF they have MEDICAL complaints) WITH THE FDA NOW!

YOU SNOOZE,
YOU LOSE.
FOREVER.

Art

P.S. DO NOT BELIEVE THE BIG LIE THAT HFA ALBUTEROL INHALERS HAVE "THE SAME MEDICINE" AS CFC ALBUTEROL INHALERS. THAT'S TOTAL BULLSHIT!!

1. HFA propellent is NOT as safe as CFC propellent! Schering-Plough says: "Rapid heart beat, vomiting, chest pain, and palpitation occurred more frequently with PROVENTIL® HFA (than with Proventil CFC).

2. HFA inhalers use ALBUTEROL SULFATE unlike CFC inhalers which use ALBUTEROL BASE. MANY PEOPLE are ALLERGIC TO SULFATES. This MAY or MAY NOT be a factor.

3. TWO OF THE THREE HFA INHALERS (IVAX/TEVA PROAIR and PROVENTIL) USE ETHANOL AS AN EXCIPIENT (to disperse the medication). MANY PEOPLE MAY SUFFER BREATHING AND OTHER PROBLEMS FROM ETHANOL, WHICH IS IN LARGE ENOUGH DOSES TO AFFECT BLOOD ALCOHOL LEVELS! CFC INHALERS USE OLEIC ACID AS AN EXCIPIENT WHICH IS HARMLESS.

4. BY FAR, WE RECEIVE MORE SERIOUS COMPLAINTS AGAINST IVAX/TEVA PROAIR HFA ALBUTEROL THAN ANY OTHER HFA.(We suspect that's because IVAX/TEVA PROAIR uses ONLY ETHANOL AS AN EXCIPIENT- unlike PROVENTIL, which uses a combination of ETHANOL and OLEIC ACID as an excipient- and is #2 in complaints.

VENTOLIN USES NO ETHANOL- and has the FEWEST complaints- but we HAVE had some BAD VENTOLIN COMPLAINTS also.

5. Are these MEDICAL PROBLEMS due to the HFA propellent, the SULFATES, the ETHANOL (except in VENTOLIN) a COMBINATION of these things, or SOMETHING ELSE? We don't know, but we DO know that SOMETHING IS VERY WRONG WITH THESE HFA ALBUTEROL INHALERS as far as MANY PATIENTS are concerned. JUST READ THE PETITION COMMENTS!

6. DEMAND THAT YOUR MD WRITE A "NO IVAX/TEVA PROAIR" PRESCRIPTION FOR YOU. DO NOT USE IVAX/TEVA PROAIR ALBUTEROL AT ALL. PERIOD. END OF STORY. IN OUR OPINION, IT IS POISON GAS FOR
ASTHMATICS. IF YOUR DOCTOR REFUSES YOUR REQUEST FOR A "NO IVAX/TEVA PROAIR" PRESCRIPTION- HE OR SHE IS AN IDIOT, AND YOU MUST NEVER ARGUE WITH AN IDIOT! JUST GET A NEW DOCTOR!

Now get over to our petition and DO YOUR PART NOW, and get yourself some nice refreshing CFC ALBUTEROL INHALERS FROM GILLESPIES while you're there.(We do not make ANY MONEY from GILLESPIES SALES of these CFC ALBUTEROL INHALERS, by the way. It's a free referral service we offer to our petitioners.)

DO IT NOW:

http://tinyurl.com/3bul5u
Dr L

Waltham, MA

#10 Jun 13, 2007
Arthur Abramson wrote:
WARRICK CFC ALBUTEROL INHALERS NOW AVAILABLE!
1. GO TO OUR PETITION AND FIND THE CONTACT INFORMATION FOR GILLESPIES PHARMACY- and remind yourself what it feels like to breathe freely again.
2. While you are there, SIGN THE PETITION TO SAVE CFC ALBUTEROL INHALERS, and MOST IMPORTANTLY, FILE A COMPLAINT BY TELEPHONE WITH THE FDA AGAINST THE NEW HFA ALBUTEROL INHALERS (phone number in HUGE RED NUMBERS- IF you have a medical complaint).
3. TELL THEM YOU WANT YOUR NAME PLACED ON THE LIST (YES, they ARE collecting names) OF PEOPLE WHO WANT TO SAVE CFC ALBUTEROL INHALERS!
ACT NOW! DO NOT WAIT!
GO HERE NOW:
http://tinyurl.com/3bul5u
You never know. We may get lucky, despite everything you've heard.
BUT EVERYONE MUST FILE COMPLAINTS (IF they have MEDICAL complaints) WITH THE FDA NOW!
YOU SNOOZE,
YOU LOSE.
FOREVER.
Art
P.S. DO NOT BELIEVE THE BIG LIE THAT HFA ALBUTEROL INHALERS HAVE "THE SAME MEDICINE" AS CFC ALBUTEROL INHALERS. THAT'S TOTAL BULLSHIT!!
1. HFA propellent is NOT as safe as CFC propellent! Schering-Plough says: "Rapid heart beat, vomiting, chest pain, and palpitation occurred more frequently with PROVENTIL® HFA (than with Proventil CFC).
2. HFA inhalers use ALBUTEROL SULFATE unlike CFC inhalers which use ALBUTEROL BASE. MANY PEOPLE are ALLERGIC TO SULFATES. This MAY or MAY NOT be a factor.
3. TWO OF THE THREE HFA INHALERS (IVAX/TEVA PROAIR and PROVENTIL) USE ETHANOL AS AN EXCIPIENT (to disperse the medication). MANY PEOPLE MAY SUFFER BREATHING AND OTHER PROBLEMS FROM ETHANOL, WHICH IS IN LARGE ENOUGH DOSES TO AFFECT BLOOD ALCOHOL LEVELS! CFC INHALERS USE OLEIC ACID AS AN EXCIPIENT WHICH IS HARMLESS.
4. BY FAR, WE RECEIVE MORE SERIOUS COMPLAINTS AGAINST IVAX/TEVA PROAIR HFA ALBUTEROL THAN ANY OTHER HFA.(We suspect that's because IVAX/TEVA PROAIR uses ONLY ETHANOL AS AN EXCIPIENT- unlike PROVENTIL, which uses a combination of ETHANOL and OLEIC ACID as an excipient- and is #2 in complaints.
VENTOLIN USES NO ETHANOL- and has the FEWEST complaints- but we HAVE had some BAD VENTOLIN COMPLAINTS also.
5. Are these MEDICAL PROBLEMS due to the HFA propellent, the SULFATES, the ETHANOL (except in VENTOLIN) a COMBINATION of these things, or SOMETHING ELSE? We don't know, but we DO know that SOMETHING IS VERY WRONG WITH THESE HFA ALBUTEROL INHALERS as far as MANY PATIENTS are concerned. JUST READ THE PETITION COMMENTS!
6. DEMAND THAT YOUR MD WRITE A "NO IVAX/TEVA PROAIR" PRESCRIPTION FOR YOU. DO NOT USE IVAX/TEVA PROAIR ALBUTEROL AT ALL. PERIOD. END OF STORY. IN OUR OPINION, IT IS POISON GAS FOR
ASTHMATICS. IF YOUR DOCTOR REFUSES YOUR REQUEST FOR A "NO IVAX/TEVA PROAIR" PRESCRIPTION- HE OR SHE IS AN IDIOT, AND YOU MUST NEVER ARGUE WITH AN IDIOT! JUST GET A NEW DOCTOR!
Now get over to our petition and DO YOUR PART NOW, and get yourself some nice refreshing CFC ALBUTEROL INHALERS FROM GILLESPIES while you're there.(We do not make ANY MONEY from GILLESPIES SALES of these CFC ALBUTEROL INHALERS, by the way. It's a free referral service we offer to our petitioners.)
DO IT NOW:
http://tinyurl.com/3bul5u
There is absolutely NO PROVEN DATA to support the allegations made. Scientific data does not support most of what the cretin states!
Dr Manishankar Butto

Waltham, MA

#11 Jun 13, 2007
hello, I am a visating colligue of seviril doctors who are on this site. I totaly agree with Dr L, a felow physisian in the same ospital. There is no data to suport these conclusion. In my country I practise pulmonary medisine in Bombay and have treated eveybodys except peoples who are in class of "untouchables". In my practise, I have cured many peoples and find now that the new medications are very good. Be very careful of asuming the worst without good data.

Since: Mar 07

San Francisco, CA

#12 Jun 13, 2007
WARNING:‘DR. L’(aka DR. VINNIGUMPA aka CHIEF PULMONARY MD aka Dr. MANISHANKAR BUTTO- ALL FROM WALTHAM, MA) IS A PSYCHIATRIC BASKET CASE AND A VERY POORLY INFORMED MD. IGNORE HIM. I TOLD YOU THAT HE WOULD CONTINUE TO CHANGE PSEUDONYMS EARLIER- AND HE HAS- AND HE WILL CONTINUE TO DO SO.)

For all intents and purposes, HFA ALBUTEROL INHALERS ARE NEW DRUGS FIRST INTRODUCED EN MASSE IN 2007- AND THE PATIENT RESPONSE HAS BEEN MASSIVELY, VIOLENTLY NEGATIVE (read petition comments here: http://tinyurl.com/3bul5u ).

Yes, it’s true that Proventil HFA was introduced in the US in 1996, but it’s also true that there have been problems reported with it, very similar to what patients are complaining about today:

Bamber MG. Difficulties with CFC-free salbutamol inhaler, The Lancet 1996; 348 (21/28) 1737

Further, common sense suggests that any patients who tried Proventil HFA since 1996 or Ventolin HFA since 2004 and had any complaints about either of them, simply went back to CFC ALBUTEROL- WHICH HAS MASSIVELY DOMINATED THE ALBUTEROL MARKET UNTIL 2007- and THIS is why HFA inhalers- particulary MARKET LEADER AND COMPLAINT LEADER IVAX/TEVA PROAIR (aka ‘MAXIMUM ETHANOL, POISON GAS FOR ASTHMATICS’)- MUST BE LOOKED AT AS THOUGH THEY ARE NEW DRUGS, because in terms of SUBSTANTIAL POSTMARKETING DATA, THEY DAMN WELL ARE!

And for the record, I DON’T TRUST ‘patient acceptance’ of HFA albuterol inhalers in other countries. Since I don’t believe the GARBAGE DATA (ie,‘CFC INHALERS HARM THE OZONE LAYER’- WHAT COMPLETE AND UTTER BULLSHIT!) that constantly spews from our own FDA and EPA, why should I trust any OTHER country’s ‘FDA’ or ‘EPA’ when they report on ‘patient acceptance’ of HFA albuterol inhalers?

The MOST IMPORTANT PROOF OF SAFETY of ANY new drug (and as I’ve explained above, HFA albuterol inhalers MUST be considered to be new drugs as of 2007) is the POSTMARKETING DATA- the complaints generated when the drug gets into the hands of patients on a large scale (read this article and show it to any MD WHO SAYS THERE’S ‘NO PROOF’ THAT HFA ALBUTEROL ISN’T AS SAFE AND EFFECTIVE AS CFC ALBUTEROL: http://tinyurl.com/2zsmyb ).

ANY THOUGHTFUL, SEASONED CLINICIAN SHOULD BE ALARMED BY THIS IMMEDIATE, WIDESPREAD PATIENT REACTION. It usually takes YEARS to uncover a new drugs major adverse reactions- in the case of HFA albuterol inhalers- it only took WEEKS! IF YOUR MD DOES NOT TAKE YOUR HFA ALBUTEROL COMPLAINT SERIOUSLY, IF YOUR MD REFUSES TO GIVE YOU A “NO IVAX/TEVA PROAIR” PRESCRIPTION (try Ventolin, try Proventil, try Xopenex- get some WARRICK CFC [see details for Gillespies Pharmacy at our petition]- BUT NEVER USE IVAX/PROAIR!)- THEN GET A NEW DOCTOR!

Good luck to all albuterol users, and if you have not yet done so:

1) sign the petition
2) file a telephone complaint with the FDA (if you’ve had a problem with a HFA inhaler- FDA # IS AT THR PETITION IN BIG, RED NUMBERS)
3) Ask the FDA to put you on the list of people who want to SAVE CFC INHALERS (YES- they ARE collecting names of people who want to save CFC albuterol)
4) Call Gillespies for some WARRICK CFC ALBUTEROL if you want it
5) AND IGNORE THIS SCHMUCK MD ‘DR.L’ aka…aka…aka…aka… FROM WALTHAM, MA!)

DO IT NOW! ALL PHONE NUMBERS (FDA COMPLAINTS, GILLESPIES DRUGS FOR WARRICK CFC) ARE AT THE PETITION:

http://tinyurl.com/3bul5u

YOU SNOOZE,
YOU LOSE,
FOREVER!

Art
Dr L

Waltham, MA

#13 Jun 13, 2007
Clinical Results

A 12-week, randomized, double-blind trial compared Ventolin HFA to CFC 11/12-propelled albuterol and an HFA-134a placebo inhaler. The trial included adolescent and adult subjects (12-76 years of age) with mild to moderate asthma. Serial forced expiratory volume in one second (FEV1) measurements showed that two inhalations of Ventolin HFA produced a significantly greater improvement in FEV1 over the pretreatment value than placebo.

A second 12-week, randomized, double-blind trial evaluated the effectiveness of switching subjects from CFC 11/12-propelled albuterol to Ventolin HFA. In an initial run-in phase, all subjects received CFC 11/12-propelled albuterol. During the double-blind treatment phase, Ventolin HFA was compared to CFC 11/12-propelled albuterol and an HFA-134a placebo inhaler in adolescent and adult subjects with mild to moderate asthma. Serial FEV1 measurements showed that two inhalations of Ventolin HFA produced significantly greater improvement in pulmonary function than placebo. The switching from CFC 11/12-propelled albuterol inhaler to Ventolin HFA did not reveal any clinically significant changes in the efficacy profile.

Additionally, a two-week, randomized, double-blind trial was conducted to compare Ventolin HFA, CFC 11/12-propelled albuterol, and an HFA-134a placebo inhaler in 135 pediatric subjects (4-11 years old) with mild to moderate asthma. Serial pulmonary function measurements showed that two inhalations of Ventolin HFA produced significantly greater improvement in pulmonary function than placebo, and that there were no significant differences between the groups treated with Ventolin HFA and CFC 11/12-propelled albuterol.

A controlled trial in adult subjects with asthma showed that two inhalations of Ventolin HFA taken approximately 30 minutes prior to exercise significantly prevented exercise-induced bronchospasm compared to an HFA-134a placebo inhaler. In addition, Ventolin HFA was shown to be clinically comparable to a CFC 11/12-propelled albuterol inhaler for this indication.(from Ventolin HFA Product Information)
ofe2

Keller, TX

#14 Sep 3, 2007
A Japonese Chiropractor gave my son 5 excercices which are based in synchronization of abdominal breathing (not from the torax), some lift weight, and in some special body posture or position. He was swimming, played soccer,and boat race...the asthma was getting worse. After one year of doing these excercices daily the asthma dissapeared. Today 30 years after he never have had an asthma problem, even we're living in Texas with a lot o allergy problems. Glad to pass them on.
Its me

West Monroe, LA

#15 Sep 9, 2007
There is also risk of cross allergy if allergic to soybeans or peanuts with ipratropium
Linda

Apex, NC

#16 Oct 9, 2007
Hum, all these double blind studies mentioned above, yet only ONE of all that BS above were HFA vs. Albuterol CFC. And even that study, according the FDA-EPA-believing Dr.s above, can not say that there is any difference between the two AND failes to mention that there IS a difference in the two by way of more negative side affects with the HFA!
Linda

Apex, NC

#17 Oct 9, 2007
Again,

Bamber MG. Difficulties with CFC-free salbutamol inhaler, The Lancet 1996; 348 (21/28) 1737
stephanie parker

United States

#18 Sep 12, 2008
The protest link to the FDA is broken ( tinyuri.com )
Marilyn L Strunk

AOL

#19 Aug 4, 2009
I have grown ver afraid of useing drugs over the years like Albuteral,its supposed too be the Same as provental HFA i have always used as some abuteral come from bad Labs, and cause ne trouble and frighten me. I have had bronkitis since I was born. and the Astma came on in 1956. Steroids are worse as they killed my daughter with the same problems as me I am 73 she died at 51. My Dr, did not know whar albuterol too give me,now I am very [email protected] m]
IWAW

Waltham, MA

#20 Aug 18, 2009
Marilyn, I'm sorry about your Daughter. I'm afraid steroids will be the death of me someday. The site below has some great info that will help you.

http://tinyurl.com/pjwfqe

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