Treating ADHD with supplements; Krill oil and Phosphatidyl Serine

[steven d]

I found out that using a high dosage of krill oil together with phosphatidyl serine has concentration enhancing properties. I use it against ADD. I find it working better then traditional meds. As a long time dexedrine user I really know what I am talking about. This is my dosage:

08:00 6 softgels krill oil.
09:00 1 softgel phosphatidyl serine.
12:00 1 softgel phosphatidyl serine.
14:00 4 softgels krill oil
15:00 1 softgel phosphatidyl serine.
18:00 1 softgel phosphatidyl serine.
20:00 4 softgels krill oil
21:00 1 softgel phosphatidyl serine.

Total: 14 capsules krill oil and 5 softgels PS.

Sometimes I also take lecithin (which is cheaper then phosphatidyl serine, but not as calming).

People who don't have ADD might also use these supplements as a mind enhancing, concentration improving nootropic.

Remember: All these supplements are fats that originate from diet and body.

The brand krill oil is neptune krill oil (2 softgels = 1.0 g neptune krill oil/ NKO) and the brand phosphatidyl serine is Nature's Way.

After taking the phosphatidyl serine I feel the substances have concentration enhancing but also calming, relaxing properties.

How does it work:

The brain cells membrane is made of fat. One of these fats is phosphatidyl serine. Krill oil has DHA/EPA connected to phosphatidyl choline. This works as an anchor and enables more phosphatidyl serine to anchor to the cell membrane. More phosphatidyl serine improves the brain electral conduction and makes the electrical signals stronger, causing more neurotransmitters to be released. Something like that...

[steven d]

I have an important message. I am changing to another brand of krill oil (azantis/ enzymotec/ arcticpure), because the previous neptune krill oil suddenly lost it's potency (suddenly it didn't work much anymore). When examining the neptune krill oil capsules I concluded that the product looked much different then before (light orange instead of the usual dark red). I am seriously thinking the product is less potent because it's less concentrated. Something must have gone wrong at production and neptune can't guarantee me their product always contains the same ingredients (which is impossible with these "natural" products; they aren't standardised). I read an article stating they had some problems due to the high krill oil demand.

[steven d]

Superba krill oil doesn't work either. Now trying Jarrow Azantis krill oil.

[steven d]

Has anyone tried this mix with what results?

[steven d]

I think I found out why the superba krill oil didn't work but Neptune did.

With great difficulty (probably due to my concentration problems) I studied the krill oil extraction patents:

Superba krill oil:

http://www.faqs.org/patents/app/20080274203

Neptune krill oil:

[url]http://patft.uspto.gov/ne tacgi/nph-Parser?Sect1=PTO2 &Sect2=HITOFF&p=1& u=%2Fnetahtml%2FPTO%2Fsearch-b ool.html&r=1&f=G&l =50&co1=AND&d=PTXT &s1=6,800,299&OS=6,800 ,299&RS=6,800,299[/url]

Superba krill oil is actually heated in order to extract the lipids and neutralize enzymes:

In some preferred embodiments, freshly caught krill is first subjected to a protein denaturation step. The present invention is not limited to any particular method of protein denaturation. In some embodiments, the denaturation is accomplished by application of chemicals, heat, or combinations thereof. In some embodiments, freshly caught krill is wet pressed to obtain oil and meal. In some embodiments, the meal is then heated to a temperature of about 50° C. to about 100° C. for about 20 minutes to about an hour, preferably about 40 minutes to denature the proteins.

But neptune krill oil isn't heated, it's washed with pure acetone or something:

After separation by filtration on an organic solvent resistant filter (metal, glass or paper) the residue is optionally washed with pure acetone, preferably two volumes (original volume of material) to recover yet more lipids. The combined filtrates are evaporated under reduced pressure. Optionally, flash evaporation or spray drying may be used. The water residue obtained after evaporation is allowed to separate from the oil phase (fraction I) at low temperature.

Very interesting is this:

U.S. Pat. No. 4,331,695 ([u]not neptune, but a traditional extraction method[/u]) describes a method using pressurized solvents which are gaseous
at room temperature, such as propane, butane or hexane. The extraction is performed at
preferred temperatures of 15 to 80.degree. C. on shredded vegetable or finely divided
animal products. The extracted oils are then made to precipitate under high pressure and
elevated temperatures of 50 to 200.degree. C. However, hexane is a poor extraction
solvent for marine animals such as krill.[b]Furthermore, the high temperatures used in the
precipitation step negatively alters the lipids.[/b]

So high temperatures should not be used when extracting krill oil. This explains why superba wasn't effective as the high temperatures may have destroyed the PC-DHA.