hotmom...you seem to know your business on drugs could you please answer a few questions for me?Politics is the only reason tramadol/ultram isn't scheduled... because its mu-1 agonist properties is similar to that of morphine. I am glad it isn't scheduled tho :0)
Tramadol IS a narcotic in that it is opioid/opiate. It binds the mu-1 receptor... just like morphine. So that is why you have withdrawal type symptoms if you take more than the reccommended amount and then stop abruptly. It produces
Supposedly the reason why tramadol is not a "controlled" substance is because it has weak 5ht (serotonin) and NE (norepi) reuptake inhibition. The neurochemicals stay in the synapse longer...which some say make addiction less likely. 5-ht inhibition also makes people feel happier (its a pr0zac nation). NE or noradrenaline/norepinepherine reuptake inhibition is believed to make it harder to get addicted to.
The 5ht and NE's reuptake inhibition also helps with pain relief. Of course the mu binding part of tramadol accounts for its opiate type relief.
While tramadol isn't considered "controlled" (scheduled)... some states (OHIO at least)have pharmacies record it as tho it were.
Being a nerd who always reads Rx sample inserts (you laugh, but this helped me DRAMATICALLY during med school pharmacology!), Tramadol can cause dependence of the morphine type.
Bottom line, it is a safER alternative to traditional opiates, but don't be lulled into the belief that you can't become dependent or addicted to it becase you can!
It is really effective at pain relief! Just don't take too much.
In 2005 I had cervical surgery with two disks being removed and a Tit plate installed. After surgery I still had neck and shoulder pain, I had had it for several years, but it was unrelated to the surgical pain which the surgery fixed.
I was placed on hydrocodone 7.5 X 3/24 for almost one year. I then visited a pain clinic and they had me on oxycontin 40 mg X 2/24 plus 10 to 20 mg/24 of oxycodone for break through pain. They also put me on Cymbalta 150 mg/24 ? and Lyrica 60 mg/24 ? these two may be in reverse, I don't remember. Along with all this I was taking 150 mg/24 of Imipramine for depression/anxiety which I had been on since 1995.
I was in my third month of the above regiment when all hell broke loose and my depression and anxiety went ballistic. I was put into a mental ward for 24 hours to see how withdrawl would go, my psych stopped all meds except my Imipramine which she increased to 200 mg and also added Ativan 1 mg as needed. After a few weeks I was feeling much better and never really had any cravings for the codiene/opoids.
All this was about eight months ago and things have been well except for off and on again neck and shoulder pain. A few days ago though, six to be exact, I got up for work and noticed more than usual pain, each day has been worse with pain between my shoulder blades, like a tooth ache at times and like a hatchet in my back at others.
I visited my GP today 5/18/07 and he put me on Tramadol 50 mg X 3/24 and Nabumetone 750 mg X 2/24. What do you think about this? He knows my history on the oxycontin and thought Tramadol might be something I could tolerate.
Do you think that Tramadol is something that a person with depression can take, long term, without having an increased chance severe depression risk? And do you know anything about Tramadol time released, is it simular to oxycontin? What do you think??
Thank you for any time you can spend on my questions.