What is Ultram?

What is Ultram?

There are 514 comments on the Associated Content story from Nov 29, 2006, titled What is Ultram?. In it, Associated Content reports that:

By Superdork Ultram, also called Tramadol, is a good analgesic designed to treat moderate to severe pain.

Join the discussion below, or Read more at Associated Content.

“Shhhhsh I'm sleeping”

Since: Dec 06

Location hidden

#25 May 18, 2007
hotmommahb wrote:
Politics is the only reason tramadol/ultram isn't scheduled... because its mu-1 agonist properties is similar to that of morphine. I am glad it isn't scheduled tho :0)
Tramadol IS a narcotic in that it is opioid/opiate. It binds the mu-1 receptor... just like morphine. So that is why you have withdrawal type symptoms if you take more than the reccommended amount and then stop abruptly. It produces
Supposedly the reason why tramadol is not a "controlled" substance is because it has weak 5ht (serotonin) and NE (norepi) reuptake inhibition. The neurochemicals stay in the synapse longer...which some say make addiction less likely. 5-ht inhibition also makes people feel happier (its a pr0zac nation). NE or noradrenaline/norepinepherine reuptake inhibition is believed to make it harder to get addicted to.
The 5ht and NE's reuptake inhibition also helps with pain relief. Of course the mu binding part of tramadol accounts for its opiate type relief.
While tramadol isn't considered "controlled" (scheduled)... some states (OHIO at least)have pharmacies record it as tho it were.
Being a nerd who always reads Rx sample inserts (you laugh, but this helped me DRAMATICALLY during med school pharmacology!), Tramadol can cause dependence of the morphine type.
Bottom line, it is a safER alternative to traditional opiates, but don't be lulled into the belief that you can't become dependent or addicted to it becase you can!
It is really effective at pain relief! Just don't take too much.
hotmom...you seem to know your business on drugs could you please answer a few questions for me?

In 2005 I had cervical surgery with two disks being removed and a Tit plate installed. After surgery I still had neck and shoulder pain, I had had it for several years, but it was unrelated to the surgical pain which the surgery fixed.

I was placed on hydrocodone 7.5 X 3/24 for almost one year. I then visited a pain clinic and they had me on oxycontin 40 mg X 2/24 plus 10 to 20 mg/24 of oxycodone for break through pain. They also put me on Cymbalta 150 mg/24 ? and Lyrica 60 mg/24 ? these two may be in reverse, I don't remember. Along with all this I was taking 150 mg/24 of Imipramine for depression/anxiety which I had been on since 1995.

I was in my third month of the above regiment when all hell broke loose and my depression and anxiety went ballistic. I was put into a mental ward for 24 hours to see how withdrawl would go, my psych stopped all meds except my Imipramine which she increased to 200 mg and also added Ativan 1 mg as needed. After a few weeks I was feeling much better and never really had any cravings for the codiene/opoids.

All this was about eight months ago and things have been well except for off and on again neck and shoulder pain. A few days ago though, six to be exact, I got up for work and noticed more than usual pain, each day has been worse with pain between my shoulder blades, like a tooth ache at times and like a hatchet in my back at others.

I visited my GP today 5/18/07 and he put me on Tramadol 50 mg X 3/24 and Nabumetone 750 mg X 2/24. What do you think about this? He knows my history on the oxycontin and thought Tramadol might be something I could tolerate.

Do you think that Tramadol is something that a person with depression can take, long term, without having an increased chance severe depression risk? And do you know anything about Tramadol time released, is it simular to oxycontin? What do you think??

Thank you for any time you can spend on my questions.

kydrby4ever

West Palm Beach, FL

#26 May 18, 2007
john henry wrote:
<quoted text>
hotmom...you seem to know your business on drugs could you please answer a few questions for me?
In 2005 I had cervical surgery with two disks being removed and a Tit plate installed. After surgery I still had neck and shoulder pain, I had had it for several years, but it was unrelated to the surgical pain which the surgery fixed.
I was placed on hydrocodone 7.5 X 3/24 for almost one year. I then visited a pain clinic and they had me on oxycontin 40 mg X 2/24 plus 10 to 20 mg/24 of oxycodone for break through pain. They also put me on Cymbalta 150 mg/24 ? and Lyrica 60 mg/24 ? these two may be in reverse, I don't remember. Along with all this I was taking 150 mg/24 of Imipramine for depression/anxiety which I had been on since 1995.
I was in my third month of the above regiment when all hell broke loose and my depression and anxiety went ballistic. I was put into a mental ward for 24 hours to see how withdrawl would go, my psych stopped all meds except my Imipramine which she increased to 200 mg and also added Ativan 1 mg as needed. After a few weeks I was feeling much better and never really had any cravings for the codiene/opoids.
All this was about eight months ago and things have been well except for off and on again neck and shoulder pain. A few days ago though, six to be exact, I got up for work and noticed more than usual pain, each day has been worse with pain between my shoulder blades, like a tooth ache at times and like a hatchet in my back at others.
I visited my GP today 5/18/07 and he put me on Tramadol 50 mg X 3/24 and Nabumetone 750 mg X 2/24. What do you think about this? He knows my history on the oxycontin and thought Tramadol might be something I could tolerate.
Do you think that Tramadol is something that a person with depression can take, long term, without having an increased chance severe depression risk? And do you know anything about Tramadol time released, is it simular to oxycontin? What do you think??
Thank you for any time you can spend on my questions.
Im not the one you directed this towards however I was on that (ultram) for 1yr.... regardless of the drugs similarities to morphine, its relief will be better on muscular/tendons then disk/nerve pain... taken in low doses and taking days off (use aspirin off days)... its will work on the stated areas/issues but the body builds up a tolerance to it very fast and thats why I say rotate w/ aspirin/Ibuprophin, to avoid the quick tolerence ... if you up the dose on your own, it wont help, itll only be useless that much sooner, dont take it around the clock, only during the bad hrs, and the rest use Ibuprph.... It isnt time released it maintains for about 3hrs (they state 4-6) but no way do I believe that (my experience is 1st hand w/ that drug)... also it has a speedy affect on you so avoid in eves prior to sleep... take in am instead... its possible that they may have a t/r version, its been a few yrs since i used it but then it was immediate release only.... if you get some relief then id say discuss taking anti inflamatories/muscle relaxers in conjunction with tramadol.. it will help alot!! and they will help w/ sleep and are non narcotic... flexerill /soma are popular brands however SOMA has an abuse factor, especially when used w/ alchohol... excuse my typing, I can spell but my hands arent as fast as my brain..... good luck w/ your pain and keep us posted....

“Shhhhsh I'm sleeping”

Since: Dec 06

Location hidden

#27 May 19, 2007
kydrby4ever wrote:
<quoted text>Im not the one you directed this towards however I was on that (ultram) for 1yr.... regardless of the drugs similarities to morphine, its relief will be better on muscular/tendons then disk/nerve pain... taken in low doses and taking days off (use aspirin off days)... its will work on the stated areas/issues but the body builds up a tolerance to it very fast and thats why I say rotate w/ aspirin/Ibuprophin, to avoid the quick tolerence ... if you up the dose on your own, it wont help, itll only be useless that much sooner, dont take it around the clock, only during the bad hrs, and the rest use Ibuprph.... It isnt time released it maintains for about 3hrs (they state 4-6) but no way do I believe that (my experience is 1st hand w/ that drug)... also it has a speedy affect on you so avoid in eves prior to sleep... take in am instead... its possible that they may have a t/r version, its been a few yrs since i used it but then it was immediate release only.... if you get some relief then id say discuss taking anti inflamatories/muscle relaxers in conjunction with tramadol.. it will help alot!! and they will help w/ sleep and are non narcotic... flexerill /soma are popular brands however SOMA has an abuse factor, especially when used w/ alchohol... excuse my typing, I can spell but my hands arent as fast as my brain..... good luck w/ your pain and keep us posted....
I appreciate your response ky...thanks, and I will post about how things go with the tramadol.

It's a tough situation when one has to deal with clinical depression and pain issues also.
kydrby4ever

West Palm Beach, FL

#28 May 19, 2007
john henry wrote:
<quoted text>
I appreciate your response ky...thanks, and I will post about how things go with the tramadol.
It's a tough situation when one has to deal with clinical depression and pain issues also.
SUBUTEX IS WRITTEN FOR W/D AND DETOX, HOWEVER VERY SOON IT WILL BE FOR LOW LEVEL PAIN AND DEPRESSION... I know if a dr puts you on 2mg every other day, it will work for the pain and minimal side effects, you will feel like your"having a good day" im including a link w/ comments on subutex and the comments from the forum posters, the upside is that it can be taken every other day and opiates will not work when your on it, easy to walk away from and your view of life(mood) will be very much positve, having a good day, all the time... and it does suppress pain!!! good luck keep me informed... http://www.naabt.org/forum/post.asp...

“Shhhhsh I'm sleeping”

Since: Dec 06

Location hidden

#29 May 19, 2007
kydrby4ever wrote:
<quoted text>SUBUTEX IS WRITTEN FOR W/D AND DETOX, HOWEVER VERY SOON IT WILL BE FOR LOW LEVEL PAIN AND DEPRESSION... I know if a dr puts you on 2mg every other day, it will work for the pain and minimal side effects, you will feel like your"having a good day" im including a link w/ comments on subutex and the comments from the forum posters, the upside is that it can be taken every other day and opiates will not work when your on it, easy to walk away from and your view of life(mood) will be very much positve, having a good day, all the time... and it does suppress pain!!! good luck keep me informed... http://www.naabt.org/forum/post.asp...
Thanks... I will talk with my shrink about this and see what she thinks. She was on vacation when this pain issue reappeared so I haven't been able to talk with her about the Tramadol, she may not like it. We'll see.

I'm not sure where the pain is coming from, I have always thought the c-6 c-7 disk was where the long term pain in my right shoulder and neck was coming from but nothing has ever shown up in mri's or mylogram <-- was a real bad experience.

The depression is the big issue for me. opoids, being depressants, cause episodes when they are out of my system, not so much on lower dose hydrocodone 20 30 mg/24, but pretty severe at higher doses in the oxycontin t/r form.

After I speak with her I'll let you know what she thinks. She is a very respected psych, she is head of the geriatric/psych department at a fairly large hospital system in Nashville. She has been my doctor since 1994, and I love her...she's really great.

I just turned 50 in April and live a pretty active life, this pain is for the birds!

Thanks again...
kydrby4ever

West Palm Beach, FL

#30 May 19, 2007
john henry wrote:
<quoted text>
Thanks... I will talk with my shrink about this and see what she thinks. She was on vacation when this pain issue reappeared so I haven't been able to talk with her about the Tramadol, she may not like it. We'll see.
I'm not sure where the pain is coming from, I have always thought the c-6 c-7 disk was where the long term pain in my right shoulder and neck was coming from but nothing has ever shown up in mri's or mylogram <-- was a real bad experience.
The depression is the big issue for me. opoids, being depressants, cause episodes when they are out of my system, not so much on lower dose hydrocodone 20 30 mg/24, but pretty severe at higher doses in the oxycontin t/r form.
After I speak with her I'll let you know what she thinks. She is a very respected psych, she is head of the geriatric/psych department at a fairly large hospital system in Nashville. She has been my doctor since 1994, and I love her...she's really great.
I just turned 50 in April and live a pretty active life, this pain is for the birds!
Thanks again...
if anything, print the comments from that link I sent, that dr from va bch made sense, I have been hearing more and more about subs as anti depressants, people go thru hell w/ pain meds but in the beginning they are a huge help w/ depression, then, when they go on subs to detox, the depression goes away, and its not like small doses are an issue w/ subs, doses of less than 1mg are possible, the 2mg pill can be cut in 1/4s and that be .5 mg and the results are huge.... and very easy to stop, also can prevent opoid use, bcuz it will block the euphoric effects yet allow you to see everything clearly... good luck!
Mel2552

Mcdonough, GA

#31 May 20, 2007
XYZ wrote:
People saying that Ultram is only "psychologically" addictive have obviously never been on it. Someone who's been on Ultram off and on for several years, I have experienced horrible withdrawals. I did not self-medicate, I took the dose prescribed. Never more than 8 a day. However, since Ultram also has SSRI (anti-depressant) properties, when you've been taking it a sufficient amount of time and then stop, not only do you go through opiate withdrawals but you ALSO go through SSRI withdrawals. Think of it as going through a codeine withdrawal and a Paxil withdrawal at the SAME time. People do not realize how horrible the withdrawals can be.
I'm on day 8 from withdrawals from Tramadol, how much longer can i expect this? I went cold turkey from 8 - 50mg. a day and i still feel sad and very off balanced and sick to my stomach???
Mel2552

Mcdonough, GA

#32 May 20, 2007
I'm just wondering how long withdrawal symptoms will last? It has been 8 days and it's a little better but i'm still very sad and still feel sick to my stomach and off balanced all the time.

“Shhhhsh I'm sleeping”

Since: Dec 06

Location hidden

#33 May 20, 2007
Mel2552 wrote:
<quoted text>
I'm on day 8 from withdrawals from Tramadol, how much longer can i expect this? I went cold turkey from 8 - 50mg. a day and i still feel sad and very off balanced and sick to my stomach???
I read on line that 1 x 50/mg of Tramadol is the same as taking 1 x 7.5/mg hydrocodone. So, 8 x 7.5 = 60/mg. This means you were taking the equivalent of 60/mg of hydrocodone per day.

If Tramadol had the same affect as hydrocodone, as far as withdrawel symptoms, You'll probably be sick for about eight to ten days, the weakness will probably drag on for another week and after that you should begin to feel okay.

I would guess that the physical dependence is about the same between the two, it would probably be the addiction or mental craving for the drug that you won't have since the opoid isn't a factor in tramadol.

“Shhhhsh I'm sleeping”

Since: Dec 06

Location hidden

#34 May 20, 2007
Mel2552 wrote:
I'm just wondering how long withdrawal symptoms will last? It has been 8 days and it's a little better but i'm still very sad and still feel sick to my stomach and off balanced all the time.
Have you ever been diagnosed with depression? If you haven't the blues should probably clear up after 10 or 15 days. If you have suffered with depression it could take a lot longer.

When I came off all my pain meds, the depression was the hardest part of my withdrawel. But, I have been diagnosed with depression and am on anti-depressants.

All the withdrawel problems you have will probably also depend on how long you took the drug. The longer you took it the longer the withdrawel I would guess.

Keep your chin up, and watch funny shows on tv for a while, stay away from sad movies, newspapers and news in general...it always seems to be sad.

Think happy...:)
kydrby4ever

West Palm Beach, FL

#35 May 20, 2007
Mel2552 wrote:
I'm just wondering how long withdrawal symptoms will last? It has been 8 days and it's a little better but i'm still very sad and still feel sick to my stomach and off balanced all the time.
the ultram /tramadol has a totally different effect on the mind/body compared to hydrocodone, I personally would see a detox specialist and lie, tell him ya been on percs/vicodin, if he will set ya up on subutex for a few days (5-10) all will be fine, energy returned no depression, time starts moving again and youll feel like your just "having a good day" 1/3 pill every other day will do it, take 1/2 2x first day and 1/3 ea day after(1st 3 days) then cut it to 1/3 every other day for a week and its over, you can cold turkey after that w/ no issue, just tell the specialist ya just stopped that day so he doesnt ask ya to go!! if he sets ya up for tem=n days youll be fine, i promise, I went from 250mg a day oxy to zero and 20+ days later no desire to use.. never a bad day...

“Shhhhsh I'm sleeping”

Since: Dec 06

Location hidden

#36 May 21, 2007
kydrby,

You mentioned early about a "speedy affect" with Tramadol, last night was my third evening taking this drug, 3 X 50/24, I took a 50/mg at about 6:00 PM and I didn't go to sleep till abt 1:00 AM this morning. I also felt kind of numb all over, very strange.

Do you think the above symptoms are due to the Tramadol?

I also read that Tramadol is quick release and that Ultram is Tramadol time release, do you know anything about this?
kydrby4ever

West Palm Beach, FL

#37 May 21, 2007
john henry wrote:
kydrby,
You mentioned early about a "speedy affect" with Tramadol, last night was my third evening taking this drug, 3 X 50/24, I took a 50/mg at about 6:00 PM and I didn't go to sleep till abt 1:00 AM this morning. I also felt kind of numb all over, very strange.
Do you think the above symptoms are due to the Tramadol?
I also read that Tramadol is quick release and that Ultram is Tramadol time release, do you know anything about this?
as far as my knowledge goes tramadol is the active ingredient in ultram, the brandname maker of the drug, any script written for tramadol is the generic for ultram... if your bottle says tramadol, beneath it it should say generic for ultram... if the drug kept ya from sleeping either take it sooner ,earlier, which is an issue, waking up in pain, or take something w/ it 1/2 xanax or anything to assist sleep, I hate to tell people to add alchohol but w/ pain med, its guaranteed to help sleep, just one measured drink! dont pound either or both...1 and 1 = good sleep....

“Shhhhsh I'm sleeping”

Since: Dec 06

Location hidden

#38 May 21, 2007
kydrby4ever wrote:
<quoted text>as far as my knowledge goes tramadol is the active ingredient in ultram, the brandname maker of the drug, any script written for tramadol is the generic for ultram... if your bottle says tramadol, beneath it it should say generic for ultram... if the drug kept ya from sleeping either take it sooner ,earlier, which is an issue, waking up in pain, or take something w/ it 1/2 xanax or anything to assist sleep, I hate to tell people to add alchohol but w/ pain med, its guaranteed to help sleep, just one measured drink! dont pound either or both...1 and 1 = good sleep....
My script just has Tramadol on it. The word Tramadol is followed by 50mg and then a TA...

I eventually did take half of a 1 mg Ativan last night and slept okay after that. I worked 12 hours yesterday, didn't get home until 7:00 PM and then ate a big dinner, that was probably why I was up so late.

I'm also taking Nabumetone 750mg 2/24, which says it is for Relafen 750 mg tab, this is an anti-inflammatory.

I checked the site about Ultram and the extended relief is written Ultram ER... I guess Ultram can come either way.
kydrby4ever

West Palm Beach, FL

#39 May 21, 2007
yes there s slow release and i/r immediate release for break thru pain.... hopefully youll sleep this time around, im opposite, if I eat a nite time, its over im down for the count!!!Marc
darcy Elvidge

AOL

#40 May 24, 2007
Mesmer wrote:
I have been taking only a small dose of Ultram for 5 months (50-100mg a day). I am trying to get off of it. I have been weaning myself off slowly, going from one pill then yesterday I only had a half of a pill and today I want to die!!!! It's not like I was taking 10 a day! Only 1 pill a day and I am having HORRIBLE withdrawel. I feel like suing the doctor who very flippantly prescribed this pill over the phone and told me it was safe. Does anyone know how long these withdrawel symptoms last on people who were only taking very little?
My comment to you is that my husband took it for 4 days and felt very dizzy and that is the last thing he said to me and died. this was almost 2 years ago. He was 62.
darcy Elvidge

AOL

#41 May 24, 2007
My husband tore his miniscus in his knee. The doctor put him on the drug Ultracet which is ultram. He got extremely dizzy and could not get off the couch . He was on it for 4 days and Saturady morning October 2, 2004 he died saying he was so dizzy. His last words.

“Shhhhsh I'm sleeping”

Since: Dec 06

Location hidden

#42 May 24, 2007
darcy Elvidge wrote:
My husband tore his miniscus in his knee. The doctor put him on the drug Ultracet which is ultram. He got extremely dizzy and could not get off the couch . He was on it for 4 days and Saturady morning October 2, 2004 he died saying he was so dizzy. His last words.
That is terrible darcy, I'm sorry for your loss. It does seem that every drug out there has death as an extreme side effect.

I'm on the anti-inflammatory nabumetone, it has poor circulation with chance for a heart attack as a side effect and also internal bleeding, it's hard to know what to do.

Tramadol has worked pretty well for me, so far, but I'm taking a fairly low dose. For people dealing with chronic pain, or any pain for that matter,the benefits vs risks needs to be considered that is for certain.

“Compromise yourself for no one”

Since: Dec 06

Cajun Country

#43 May 24, 2007
darcy Elvidge wrote:
My husband tore his miniscus in his knee. The doctor put him on the drug Ultracet which is ultram. He got extremely dizzy and could not get off the couch . He was on it for 4 days and Saturady morning October 2, 2004 he died saying he was so dizzy. His last words.
I'm curious as to why he continued to take the medication for 4 entire days with the side effects he was having.
That strikes me as rather odd.
If something made me feel like that, I wouldn't have taken it a second time without calling my doctor.

I've never had one of my patients call me and tell me that they became dizzy with Ultram or Ultracet. If they did, I'd have them discontinue it and provide them with a substitute.

“Shhhhsh I'm sleeping”

Since: Dec 06

Location hidden

#44 May 27, 2007
aLifeUncommon wrote:
<quoted text>
I'm curious as to why he continued to take the medication for 4 entire days with the side effects he was having.
That strikes me as rather odd.
If something made me feel like that, I wouldn't have taken it a second time without calling my doctor.
I've never had one of my patients call me and tell me that they became dizzy with Ultram or Ultracet. If they did, I'd have them discontinue it and provide them with a substitute.
I wondered the same thing when I first read her post, I guess it all depends on how much pain he was in and just how "dizzy" dizzy is. By this I mean if her husband was in severe pain and the Tramadol wasn't helping much, and the dizziness was not too
bad, he might have thought the pain was the reason.

aLifeUncommon,

do you ever put a patient who is taking Tramadol, with some success, but needs something a little stronger from time to time, on hydrocodone? I have had some good days on Tramadol but on other days it doesn't seem to work very well. Do you think a combination of the above two drugs might be a reasonable option for someone with chronic back pain?

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