Reduced Cardiac Vagal Modulation Impacts on Cognitive Performance in Chronic Fatigue Syndrome
There are 1 comment on the Free Republic story from Dec 30, 2012, titled Reduced Cardiac Vagal Modulation Impacts on Cognitive Performance in Chronic Fatigue Syndrome. In it, Free Republic reports that:
Cognitive difficulties and autonomic dysfunction have been reported separately in patients with chronic fatigue syndrome .
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#1 Jan 11, 2013
This study demonstrates some of the construct difficulties in researching this disease. Myalgic encephalomyelitis (chronic fatigue syndrome) has a number of transdiagnostic symptoms. A common caveat with medical populations is that symptoms that commonly occur with disease, including fatigue or loss of energy, changes in sleep patterns and cognitive difficulties, may be misinterpreted by healthcare providers, researchers or patients as mood-related particularly when specificity and severity are lacking.
As well, many of the instruments used to diagnose mood disorders can become a confounding variable in medical studies.(Jason et al 2012) So does the failure to separate patients with psychosocial overlays from patients without depression or anxiety as well as differentiating between patients with pre-morbid psychiatric illness and patients without.
As well, there are multiple definitions used under these umbrella terms that define very different populations ranging from the very heterogeneous (White et al 1991) to the narrowly defined (Caruthers 2011) some of which may have mood disorders only (Jason et al 2012). This can limit extrapolation of results between groups.
A search of the literature reveals demonstrated cognitive symptoms in ME and CFS including processing-speed deficits and working memory impairment - which are also found in MS for example.(Tiersky et al 1997; DeLuca et al 1997, 2004; Busichio et al 2004; Lange et al 2005).
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