Topamax can diminish sex drive

Topamax can diminish sex drive

There are 37 comments on the The Seattle Times story from Dec 14, 2008, titled Topamax can diminish sex drive. In it, The Seattle Times reports that:

Q: Does Topamax cause complete lack of sexual desire? And I do mean complete! A: Topamax is prescribed for epilepsy, but it also is used to prevent migraines.

Join the discussion below, or Read more at The Seattle Times.

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Luton, UK

#1 Dec 31, 2008
Has anyone had the problem where it has affected their sex drive completely?
I am using it to prevent migraines. Been on them for about 6 months and they are doing the job brilliantly, other than this side effect.

Terre Haute, IN

#2 Jan 2, 2009
I've been on it for almost 2 years for migraines and have the same side effect. I also get tingling fingertips!
Djidenou Sonouvi


#3 Jan 7, 2009
I am not using Topamax , my wife is but I am victim of two side effects: first she does not like sex anymore unless I persuade strongly. Second whenever we have sex I have the same side effects like her : drowsing, coordination, etc... Can Topamax be passed through genital secretions or saliva?

Skokie, IL

#4 Jan 9, 2009
it is the worst drug in the world i was on it after brain surgery and it almost killed me

Tucson, AZ

#5 Jan 26, 2009
Topamax is my miracle drug!! I am 54 yrs old. Have been taking Topamax for 3 yrs. I had back surg to remove a bone shard that broke off- no narcotic pain meds, back injections, physical therapy for months or ANYTHING helped the pain. Then my Neurolgist suggested trying Topamax as a last resort. It took 2-3 wks of nasty side effects to get used to it. However, I no longer suffer the severe sciatic and back pain, no longer have the SEVERE 2-3 day long cluster migaines I have suffered since I was 13 yrs old and have lost 60 pounds without even noticing them leaving. I DO have the sexual side effects (NO SEX side effects), have the mild memory loss and occassional numbness and tingling in fingers and hands but to be able to work and raise 2 and 6 yr old grandchildren almost pain free after NOTHING else worked is nothing short of a miracle!! THANK YOU TOPAMAX FOR GIVING MY LIFE BACK !!

Tucson, AZ

#6 Jan 26, 2009
I am, however, waiting breathlessly for the generic Topamax to come out!! Especially in these very difficult financial times the name brand is very expensive (even my co-pay). It is very difficult for me to consider not taking it but if I were to become, as some of my friends have recently, unemployed, and lose my insurance I would probably not be able to aford such a cost prohibative medication at all.

Newport Beach, CA

#7 Jan 31, 2009
I have been using topamax for (gosh) 5-6 yrs? I use it as a mood stabilizer. An added benefit is that it reduces my migraines, like others. I honestly have had very few side effects aside from the initial first month (ocular pain, numbness in the hands/feet). I didn't mind the word loss/memory loss.(I could use the memory loss/recall.) I also take a relatively low dose (75 mg once daily at night). I have had no sexual side effects whatsoever. The only thing that has affected my sex drive is pregnancy and breast feeding.
Btw, I love the weight control/appetite control aspect. I feel fit, healthy and young. I secretly fear ever going off of the med purely for vanity sake.
Also, before topamax, I was using depakote. That was a nightmare! I gained 45 lbs. in 4 months. I am a petite woman. Not good. My body and liver was toxic with valporoic acid build up, etc. My skin and tissues were purple, tender and bloated. Yuck! That's when I had no sex drive.

Topamax has been a dream since. I would never go back. I would persoanlly talk to my doc and look at other potential complications (drug interactions, life stressors/transitions, hormone levels, curent relationships -work, romantic, parental, etc.).
Best of luck.

Tonganoxie, KS

#8 Feb 11, 2009
Okay--the truth is, my wife never had orgasms (ever) until she took Topamax. But its only at a very narrow range of dosage that it worked that way, and it took a long time--in small increments--to find the precise dose (around 375mg). All I know is that for her and her sex life it made a wonderful difference. Might be something for some women to try...
Roberta Levine

Fremont, CA

#9 Aug 11, 2011
Of the many studies conducted on the side effects of Topamax, not much has been said about it affecting the sex drive of a person. However, it is the least problem among Topamax side effects because the birth defects are considered as the most serious discovered by far. I find it that this website would provide more information:
Psychiatry Video You tube

Irvine, CA

#11 Nov 24, 2011
"Making A killing"

Give it 2 minutes.

Circle Pines, MN

#12 Dec 4, 2011
I have been on Topamax for years for my Epilepsy. It has never caused issues with my sex drive, ever.=)
I was on Depakote for a while, which made me depressed, miserable, FAT, and didn't help the seizures much either. they put me back on the Topamax and the weight came flying off, I was happy again, my mood was great! Sex drive back again. I even heard they were thinking of putting it on the market as a weight loss pill...?

Whittier, CA

#13 Jul 7, 2012
I have been taken the generic type topiramate form for two months now for petit mal and i feel great, a little tingling in the toes and less apetit and yes my libido is a little on the low side now and im always Thirsty and i also notice im a but slow and my memory sucks BUT... i rather have all that than feel dizzy , drunk like and confused like i used to before the medication. topiramate is really afordable only 199 dlls for a months worth, 100 ml a day


#14 Jul 22, 2012
Ive been on topamax for 9 months for migraines and my doseage is now at 200mg daily its been this for about a month now! I'm feel very anxious on it and most days I'm very irritable! My sex drive is non exsistant and I feel so bad for my husband as he has been so patient and understanding through all this, has anyone else experienced lose of sex drive with it as it's putting a lot of pressure on us xx


#15 Aug 7, 2012
I googled Topamax and sexual dysfunction because I wondered if anyone else had been experiencing the same thing I had. I took it over about a four year period and my orgasm was almost nonexistent. I wasn't sure if it was the Topamax that was causing this as I was taking other medications also. I have been off of the Topamax for seven months now and after about two or three months my orgasm was back to full intensity. Just thought I'd share and maybe others have experienced this?

Dearborn, MI

#17 Oct 6, 2012
I am on 300 Topamax. NO SEX drive at all. Very unusual for me. My Rx ran out & I have been off for 5 days. Sexual effects 100% gone. This started with a dose increase. Hoping if we decrease dose sexual effects do not return.

Medicine Hat, Canada

#20 Jan 23, 2013
So torn! I've been put back on this for nerve damage to a leg and arm & it's only been 24 hours & already I remember why I went off it! Sex drive went on me last time within one week & I LOVE PEPSI & it tasted absolutely TERRIBLE! So tonight I had a Pepsi and against is AWFUL😖. I LOVE Pepsi and its my only vice! So I think I can give up the Pepsi for a while but I'm praying that the sex drive doesn't take a dive again! I'm only 52 and far from dead😃👍 . But it CAN be a side affect.

Medicine Hat, Canada

#21 Jan 23, 2013
PS. Sorry for the #'s that showed up. They must have been put in place of my smiley faces etc.....

Modesto, CA

#25 Jan 28, 2013
I buy topamax from
Robbie Enderson


#26 Feb 4, 2013
I have ordered prescription drugs (without a prescription) online from about two years ago, and was pleased with the speed and quality of service.
I'm thinking of doing the same thing with my medication. The meds is expensive, but there is a generic version available overseas.
I love the idea of taking responsibility for my own health (or lack of health) and skipping the bureaucracy... to say nothing of having to drive to the doctor, wait in line, yet again, to get a prescription refilled.

Plymouth, MI

#27 Feb 14, 2013
Lindy wrote:
I googled Topamax and sexual dysfunction because I wondered if anyone else had been experiencing the same thing I had. I took it over about a four year period and my orgasm was almost nonexistent. I wasn't sure if it was the Topamax that was causing this as I was taking other medications also. I have been off of the Topamax for seven months now and after about two or three months my orgasm was back to full intensity. Just thought I'd share and maybe others have experienced this?
Yes I experienced the same thing. I have been on the generic brand of Toamax for several years now, but have up'd my dosage to 50mg twice a day for a bout a year now and have now started having problems achieving orgasms. I am taking the medication to treat migraines. So, what does a person do when your boyfriend things he's the problem. I am going to back off of my medication and see if the medication is the problem. Thank you for your post I have wondered if it was the medication causing the problem.

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