Effect of not taking 1200 mg of seroquel for 3 days

[Steve]

I am an attorney with a client who is taking 1200 mg of Seroquel a day for schizophrenia and has been for 9 months. Two questions: 1. The jail pharmacy ran out of the prescription for 3 days before he was interviewed for a sanity evaluation. How might that have effected his performance. 2. Anyone have any experience with that high of a dosage

[Brigid]

Seroquel has a nasty withdrawal including severe intractable insomnia, restlessness, irritability, anger, rage, psychosis ( hallucinations, delusions, paranoia) It should not be stopped abruptly, but gradually tapered down. 1200 mg. a day is a high dosage and would tend to be very sedating. I hear that they keep many in the prison population sedated on such high doses of antipsychotics so that they are more compliant.

[Steve]

Brigid--Any sources that I can use to cross examine a psychiatrist on this information.
Thanks

[Brigid]

Unfortunately, the drug companies are less than forthcoming about the withdrawal effects from Seroquel and other psychotropic meds. They do not fund and/ or manage to supress much of the data. Most of the research I know of is anecdotal in nature for this reason. I hope the following sites will help you and your client.
http://bipolar-disorder.emedtv.com/seroquel/s...
http://www.psychdrugtruth.com/seroquel_withdr...

[Omi]

Dear mr. attorney :)
I'm quite sure, that if you take 1200 mg seroquel (i suppose you habe no schizophrenia) yourself for some weeks, and get off of it like that, you wouldn't come through sanity evaluation either. But then again, high doses of Seroquel can be quite disableing (and even make some not-psychotic folks hear voices).
other than that, i dont even think such high doses have been researched (yet). so chances are, if your client is really THIS schizophrenic, he might be quite better off with a higher potency or less sedating neuroleptic (risperdal, amisulpride, sulpirid, maybe zyprexa) which dont cause so much sedation and works in the mg range and not the gramm range. these are also less sedating although they can slow down the thought process more. they basicly leave the person calm and retarded but at least awake and responsive.
BTW in my opinion, taking someome suddenly off of so much seroquel is BATTERY AND TORTURE. Sue them.