I tried Actonel 150 mg monthly dose last month. I was sick for 4 days and had bad depression during the 4 days and a day or two each week. I told my doctor and he gave me samples of Evista to take this month. I'll be starting it in a couple weeks. I'm hoping that I won't have the bad side effects that I had with Actonel. Did anyone have trouble with depression while on Evista? I haven't read that it makes people sick to their stomach the way Actonel does so I'm not expecting to be sick again. Any information will be appreciated. Thanks.