A persons body chemistry might react differently with different types of fermented and distilled beverages. Though, the actual alcohol is the same in all products....the source of which that alcohol is made is very different.
Cactus, grapes, grains and the like have many differnt componants to which some may be allergic either to a small or large degree. Which would, of course, make completely different reactions in a test group. And could really affect your buzz.
btw: triple sec is usually very low in proof. you might have to drink quite a bit of it to get your buzz on.