Can Singulair Cause Depression?

There are 20 comments on the Apr 4, 2008, About Depression story titled Can Singulair Cause Depression?. In it, About Depression reports that:

On March 27 the FDA issued a safety alert regarding the asthma medication Singulair . via About Depression

Join the discussion below, or Read more at About Depression.

First Prev
of 2
Next Last
GypsyGirl

Conyers, GA

#1 Nov 9, 2008
I have taken Singulair on and off for the past eight years. In that time I have had a series of self distructing events. All of witch occured on the drug. I never connected the two until the past week. I was given the drug on Wednesday. Today is Sunday and I have had severe nightmares, Irrational thoughts, such as leaving my husband and suspecting he wants to leave me, though we've been together since I was 14 and have a wonderful relationship. I think that for a lot of people this is a wonder drug, but for others it is a wonder they stay alive through it! Please, monotor your thoghts and feelings on this drug and stop right away if you even feel a little sad or irrational, there are other alternatives. Please, don't ruin yourself. I should have laid a foundation for my life in my 20's instead, I spent most of that time feeling like I was going crazy and being self distructive and unstable. I haven't taken it in two years and things have been better until this past week!!!
shargram

Norwalk, CT

#3 Feb 5, 2009
GypsyGirl wrote:
I have taken Singulair on and off for the past eight years. In that time I have had a series of self distructing events. All of witch occured on the drug. I never connected the two until the past week. I was given the drug on Wednesday. Today is Sunday and I have had severe nightmares, Irrational thoughts, such as leaving my husband and suspecting he wants to leave me, though we've been together since I was 14 and have a wonderful relationship. I think that for a lot of people this is a wonder drug, but for others it is a wonder they stay alive through it! Please, monotor your thoghts and feelings on this drug and stop right away if you even feel a little sad or irrational, there are other alternatives. Please, don't ruin yourself. I should have laid a foundation for my life in my 20's instead, I spent most of that time feeling like I was going crazy and being self distructive and unstable. I haven't taken it in two years and things have been better until this past week!!!
My Granddaughter has been on it for 4 years and is depressed has mood swings and is school phobic! I want to ask her Dr to try another med. to see if there is a change in her personality but I'm afraid a new med. will not work as well!
kimberly balmer

Philadelphia, PA

#4 Sep 8, 2009
i'm 13 and i have taken singulair for the past 5 years, and now i have started to have suicidal thoughts and have been cutting myself for three years.when my parents and friends found out they were very confused, i was confused as well.i never thought of myself as depressed because i had a good life, friends, family, a suportive boyfriend and i still was depressed.after a few years of suicidal thoughts returning, my mom finally researched my condition online. she found a lot of studies about my allergey medication, Singulair.in these studies, she found many cases of suicide, suicidal thoughts, and depression reported after the drug was F.D.A approved.she took me off the medication and sought help from my doctors. i'm finally able to look forward to a bright future filled with happiness.
Jpharm

Weatherford, OK

#5 Sep 22, 2009
In rare cases, psychiatric disorders including agitation, aggressive behavior, abnormal dreams, depression, and suicidal thinking have been reported.-source Sigler medical publishing and Epocrates digital drug reference.

This may be happening, but advice here it isn't the end all be all. The internet is not substitute for a real doctor. If you are taking singular for allergies, there generally are plenty of meds that may substitute. However if you are taking it for asthma, it will probably mean switching to an inhaled corticosteroid, or combo inhaler such as Advair. This may be problematic, but it may verify that singular is or isn't the problem.

Good Doctors don't magically take a way a med that works, but they do compare the risk vs benefit to the patient. You should keep your doctor informed so he can help you find the right med, even if it is OTC instead of RX.
ally

United States

#6 Sep 25, 2009
OMG I can't believe what I am reading I was put on singulair a month ago and lately I have been so sad and unsure of myself and I am driving my boyfriend nuts...I am not my usual happy go lucky self. I went from go with the flow to trying to control my surrounds and have unexplained fear and panic. I just called my doctor so I just wanted to thank all of you for your posts.
shargram

Norwalk, CT

#7 Oct 22, 2009
My Granddaughter was on this drug for 3 years and was totally out of control, failing school, mood swing you name it! Took her off it and there was a complete change within 1 month! She is doing just fine without it!
vip

United States

#8 Nov 16, 2009
I started taking "Singulair" during the summer of 2006. I took it for asthma. I did not feel any suicidal thoughts, however it was affecting my emotions. When I was worried about something I would become extremely fearful. Or when I felt happy, I would become too excited. In other words, it seemed to intensify my emotions to an extreme. I stopped taking singulair in Dec 2008, and after 2 days immediately I felt more clear-headed, able to articulate easier, and control my emotions. I have since been taking "Xolair" and have never felt better. But the only reason Xolair works good for me is because my doctor discovered that I have "Allergic Asthma". If you are on Singulair like I was and are looking for an alternative, ask your doc to test you to see if you qualify for Xolair therapy instead.
MOM of 3

United States

#9 Dec 1, 2009
My son is 11 years old and has been on singular since he was around 3 years old. Last year he started getting really depressed. About 3 years ago he strted waking up in the middle of the night with night terrors. It was horrible for the whole family. He went through testing all night at the hospital where they found everything to be normal. But the Dr. did say that they have had kids that were on singular have the same symptoms but couldnt diagnose that because there hadnt been enough studies. Well awhile back I took him off and he started acting like himself again and has not had any night terrors. And these night terrors had lasted for about 3 years off and on. Now I am hearing all kinds of stuff about suicidal thoughts and depression are side effects of this drug. That is really scary to me because I use to hear him say he just wanted to die and how sad he always was. I believe I am going to keep my child off this drug and talk to the Dr about other ways to help prevent his flare ups of asthma. I think more people need to know about this too it is very important information.
marika

San Francisco, CA

#10 Dec 4, 2009
has anyone experienced or heard of symptoms of depression or anxiety getting worse after stopping Singulair? My 14 year old recently went off Singulair after 6 months on it, and at the same time began to experience aggression, anxiety and depression, way beyond usual teen angst. She went off the medication unbeknownst to me, and we just realized that it coincided with her sudden behaviour and mood changes. Any one with any experiences with this or suggestions?
Jenna P

Washington, DC

#12 Dec 28, 2009
marika wrote:
has anyone experienced or heard of symptoms of depression or anxiety getting worse after stopping Singulair? My 14 year old recently went off Singulair after 6 months on it, and at the same time began to experience aggression, anxiety and depression, way beyond usual teen angst. She went off the medication unbeknownst to me, and we just realized that it coincided with her sudden behaviour and mood changes. Any one with any experiences with this or suggestions?
Actually yes. I never considered my depression to be related to my allergy medication. I'd just moved to a new city after nearly 30 years at home and just chalked it up being home sick and being somewhere new. I'd also thought it had something to do with the birth control I'm using to regulate menstruation and extraordinary mood swings. But thinking back, those subsided once I started on the birth control and then started back up shortly after starting singulair a couple months later. Recently, I had to stop taking Singulair cuz my insurance lapsed from my old job and I ran out of pills. It's been a little over a month since I took anything regularly and I've experienced ridiculous mood swings, depression, lack of confidence, unreasonable anger towards my roommate and all around feeling crappy about life. Thanks for posting this. It makes a world of sense.
mark

Encino, CA

#13 Dec 28, 2009
i quit because it works through neurotransmiters and i was on antidepressants (and not feeling human or feeling at all). i also quit the antideprants and started to feel better. a week later i let my parents know and my father told me he quit because of emotional side effects. and if they are going to tell me my ace inhibitor may cause me to have a dry cough but they wont tell me it will make me want to kill.
Anonymous

Stow, OH

#14 Mar 12, 2010
Singulair not only works extremely well for my asthma and allergies, it also HELPS my depression and anxiety -- I feel very calm and level on this stuff. Go figure!
John

San Diego, CA

#15 Mar 20, 2010
I find a good source about Singulair (Montelukast)- http://montelukasts.com At this site I find a lot of useful information - dosage, side effects, description.
jrk

Tacoma, WA

#16 Apr 28, 2010
marika wrote:
has anyone experienced or heard of symptoms of depression or anxiety getting worse after stopping Singulair? My 14 year old recently went off Singulair after 6 months on it, and at the same time began to experience aggression, anxiety and depression, way beyond usual teen angst. She went off the medication unbeknownst to me, and we just realized that it coincided with her sudden behaviour and mood changes. Any one with any experiences with this or suggestions?
Yes! our 9yr old son has been off singulair for the last week, and has never been worse: anxiety, crying jags, panic, stomach trouble, etc. each day is better but we can't wait for this to be out of his sytem!
JbAA

Washington, DC

#17 Aug 19, 2010
marika wrote:
has anyone experienced or heard of symptoms of depression or anxiety getting worse after stopping Singulair? My 14 year old recently went off Singulair after 6 months on it, and at the same time began to experience aggression, anxiety and depression, way beyond usual teen angst. She went off the medication unbeknownst to me, and we just realized that it coincided with her sudden behaviour and mood changes. Any one with any experiences with this or suggestions?
YES! I had just finished my junior year of high school and everything was going perfectly. I have always been extremely happy. I had been taking singulair for about 2 months for seasonal allergies and then I stopped in late june because I ran out. I shortly after realized that I could not think anymore and it was very scary. Everything death spiraled from there and I began to think I was dying or had a brain tumor. Over the past two months I have experienced extreme anxiety and depression, and the doctor says it is probably an anxiety disorder. Worse yet, after about a month of suffering I went back to the allergist and he re-filled my prescription for singulair and had me start taking it again. I just stopped taking it yesterday and I am hoping the damage is not long lasting or permanent. I'm thinking of filing suit because singulair has made the last two months of my life a living hell.
Jaime

Pittsburgh, PA

#18 Sep 14, 2010
I have been on Singulair since last Feb.I am 34 year old healthy female. Since then i have been having very vivid dreams and heard loud crashing noises that have woken me out of a dead sleep! my boyfriend laughs and tells me its ghosts in his house! Recently I have been very anxious and depressed,its almost becoming my "normal" and i dont like it!I tried quitting a few times and my allergies where too unbearable so i began taking it again.Has anyone else experienced any of this??
Krissi

United States

#19 Feb 2, 2011
My doc put me on Singulair one month ago for eosinophilic esophagitis. I normally don't have trouble with depression or anxiety. I'm also healthy and usually feel great. After being on Singulair for about 15 days, I began to feel very depressed and anxious. I have also been feeling like I have a bad case of the flu complete with body aches, sore throat, earaches, a nasty cough, and a high temp (around 103). I have an appointment with my doc tomorrow and I'm going to beg him to take me off this med. This feeling is NOT me!! I'm glad to see it's not just me who has trouble with this med.
Sara

London, UK

#20 May 16, 2011
Thank you all for your stories, it is very comforting to hear I'm not alone! I was prescribed Singulair following a breast augmentation to prevent hardening of the implant and I have not been my happy, cheerful self ever since I started taking the drug 6 weeks ago. I have tried very hard to understand what is wrong and why I feel so down and sad and decided to look up side-effects of this drug when I found this forum. I too do not sleep as well as I used to and feel generally not like myself. I will finish the prescribe dose of the drug (3 months) but I would not want to keep taking the medecine for a long period of time but try to find alternative drugs. Thank you!
AnnaP

Olney, MD

#21 May 19, 2011
jrk wrote:
<quoted text>
Yes! our 9yr old son has been off singulair for the last week, and has never been worse: anxiety, crying jags, panic, stomach trouble, etc. each day is better but we can't wait for this to be out of his sytem!
I know it's been a year since your comment but I just wanted to know if things have improved for your son and how long it took. I really hope that he is better. My son is 9 and took Singlair for 5 years. We took him off (10) days now and noticed a big improvement in his mood and concentration. As if a big cloud was lifted. But some symptoms have continued and intensified (hallucinations and anxiety attacks).
Anne

Willow Springs, IL

#22 Aug 11, 2011
My Dr. gave me samples to try this for severe allergies, but after reading all these comments, not even going to consider it. Thanks all for your information. I just hope my Dr. doesn't give me crap about it. You know, they think we are all stupid.

Tell me when this thread is updated:

Subscribe Now Add to my Tracker
First Prev
of 2
Next Last

Add your comments below

Characters left: 4000

Please note by submitting this form you acknowledge that you have read the Terms of Service and the comment you are posting is in compliance with such terms. Be polite. Inappropriate posts may be removed by the moderator. Send us your feedback.

Merck Discussions

Title Updated Last By Comments
News Merck's mumps vaccine clinical tests were total... Mar '15 Vaccines Cause ADHD 13
News Merck grants free license for pediatric HIV drug Feb '15 VACCINES MAIM KILL 1
News Merck senior management tried to pay off its ow... Feb '15 followthecrowdoff... 1
News Merck's MSD Pharma to create 800 jobs in India (Nov '08) Dec '14 BASAVARAJ G 221
News New Gardasil vaccine protects against additiona... Dec '14 PHARMA MISINFO 1
News Merck's shingles vaccine, Zostavax, recommended... (Jun '08) Aug '14 Susanna 75
News Pfizer, Merck 1Q sales boosted by acquisitions. (Jun '12) Jun '14 Darryl 17
More from around the web