To whom it may concern:

My case is relative to COX-2 inhibitors (VIOXX in particular) ruining bone/spinal repair operations that I have had (many). All Pre-VIOXX were tremendous successes; all of the POST-Vioxx ops. were failures, which severely damaged my life - and were due to taking VIOXX during the recovery time – before, during, and after, not skipping a beat -(no-one was ever warned - even though Merck most likely knew).

This clearly shows the devious and arrogant behavior by Merck, consistent with its actions with the heart cases. In fact, I can only believe that knowing what I have to say could affect the heart cases to the detriment of Merck.

Thank you for you consideration.

Sincerely,

Dennis Harrison
Hurley, NY
dennisharrison@hvc.rr.com (845-231-3272)

Just a couple of articles of MANY news articles – unfortunately Merck never disclosed info to the Medical community.

COX-2 inhibitors may interfere with bone growth, healing - By SARA SELIS

Researchers at the medical center have found that selective COX-2 inhibitors — a class of medications widely prescribed for painful inflammatory conditions such as osteoarthritis and rheumatoid arthritis — interfere with the healing process after a bone fracture or cement less joint implant surgery. Their findings, published in the November issue of the Journal of Orthopaedic Research, suggests that patients who regularly take COX-2 inhibitors should switch to a different medication, such as acetaminophen or codeine derivatives, for a period of time following a bone fracture or cement less implant…

Stanford Univ. Med. Cntr.- Researchers show COX-2 inhibitors interfere with bone growth, healing

Researchers at Stanford University Medical Center have found that selective COX-2 inhibitors - a class of medications widely prescribed for painful inflammatory conditions such as osteoarthritis and rheumatoid arthritis - interfere with the healing process after a bone fracture or cement less joint implant surgery. Their findings, published in the November issue of the Journal of Orthopaedic Research, suggest that patients who regularly take COX-2 inhibitors should switch to a different medication, such as acetaminophen or codeine derivatives, following a bone fracture or cementless implant. The study, conducted in rabbits, also suggests that physicians should consider changing prescribing patterns since many doctors commonly prescribe anti-inflammatory drugs including COX-2 inhibitors under the very circumstances in which the drugs should be avoided…

…and there are MANY more news articles citing many other testing results: