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hazmat535

Bethlehem, PA

#1 Jul 18, 2010
Hi,

I was just prescribed Exalgo, a once-a-day, time released pain killer that uses a push-pull sysytem to deliver a constant dose of hydromorphone.

Out of curiosity I tried to cruch one without very much luck. I then proceeded to cut the pill in half & found (inside) one half was a VERY TIGHTLY COMPACTED white matter & the other half was a very tightly compacted gray matter. The whole thing is surrounded by what seems to be a pretty heavy-duty plastic-type shell with a pin-point hole in the center of the one side. My understanding is that the "hard candy shell" is passed out through the stool after the drug does its job in your digestive system.

So....doe anyone have any experience with these new Hydromorphone ER pills yet? They seem to be pretty abuse resistant. Just curious what others have experienced.
Kelly

Starkville, MS

#2 Aug 19, 2010
Yea I hope you didnt take it after you cut it - if so it could very well kill you. Its a fabulous medicine that has really helped my husband better than anything he has ever used. Sounds to me thought that you are looking for a means to abuse otherwise why on earth would you cut it - freaky
ttaM

Bronx, NY

#3 Aug 19, 2010
I've experimented by cutting & skinning them of their tough plastic shell as well. From online diagrams of exalgo pills online I believe the white side is the hydromorphone layer & the dark stuff is the push/pull stuff to make it release throughput that little hole in the center. I have had an impossible time getting the white substance to flake up or be ground into a fine powder so the best I can do now is swallo it. If I have 2 16mg ones at once I feel the effects very minimally. I'm usually taking 200 - 220 mg of Opana daily as per my dr's prescription, and after giving exalgo a shot for a few weeks it proves that Opana Is what works best for me.

Anyone else taking two 40' er opana ER twice daily & 4-6 10mg opana IR for breakthrough & still not getting what I consider adequate improvement with my pain? Any suggestions? I will sometimes take up to 320-400mg of Opana per day on bad days & i can still function perfectly fine.I realize that I'm on a pretty high level of Opana, but my insurance covers it & I only pay $50 total per month for 120 40mg er & 180 10mger.

I've tried Methadone, all the different morphines out there & now finally exalgo without nearly the effectiveness of opana.

I hope I'm not threadjacling too bad, but I've never posted before.

tt
Sinwillfindyou

United States

#5 Sep 2, 2010
Thanks all of you for honesty and yer drop dead sexiness. Lol. I am currently on 4 40 mlg opana er and 2 10 mlg opana ir and today my doc recommended exalgo but I think I will refuse his offer. Opana really is the host with the most. Well...I guess I'm the host..so it offers it's host the most...or Some crazy thing like that. Chronic pain is a bitch and anyone out there asking why we would abuse our own meds the answer is because to get the relief I get from opana taking it orally I'd have to probably take ten at a time and I've yet to meet a doc willing to do that! Don't judge till you've had severe nerve damage. And come to think of it, even if you do, you don't have mine. I've found a way to go about my day without self medicating with street drugs or using needles with ANY drugs. Not that I'm judging you if that's what it takes to get yer shoes on in the morning. Crippled rock stars are people too! Just harder to look at or god forbid have sex with! But for those few beautiful ladies that do...god bless each and every molecule and even the atoms that make up those molecules!!! So to wrap it all up with a nice polka dot bow...eat yer veggies, we all have our cross to bear, booze is for squares, and sex with handicapped folks builds strong bones and healthy teeth. Good nite everybody and good luck....ok sorry, I'm a writer and I felt a touch inspired all of the sudden. One love.
sr poopalot

Chambersburg, PA

#6 Nov 7, 2010
take the exalgo and get plyers and crush it. i do that with 2 16 mg exalgos and it works good
pjay140II

Salinas, CA

#8 Dec 18, 2010
sr poopalot wrote:
take the exalgo and get plyers and crush it. i do that with 2 16 mg exalgos and it works good
im thinkin bout changing from the new shitty version of oxy,[the op 80's] to the exalgo. or dilaudid er basically. thanks for the 411. but wut about the inner white/grey split. wutcha do with that?
dilaudid8

Dearborn Heights, MI

#9 Jan 27, 2011
the most powerful pill iS THE dilaudid8 this I no for sure 100 percent I have snorted and took the opana 40 mg and they suck big time but they came out with a fentanyl pill dont no how good it is but going to give it a try
lyt

Theodore, AL

#10 Mar 16, 2011
im scared to half th 12mg exalgo
beline

United States

#11 Apr 23, 2011
Yes the white part is the good stuff. Take a hose clamp and shave it as best as u can. Either eat it or snort it as best as you can. Its best to swallow the white part as it will work better. I was prescribed it also and I find that it sucks. If you have a tolerance to pain meds you will NOT die!
Polaroid-Princes s

Arvada, CO

#12 May 20, 2011
beline wrote:
Yes the white part is the good stuff. Take a hose clamp and shave it as best as u can. Either eat it or snort it as best as you can. Its best to swallow the white part as it will work better. I was prescribed it also and I find that it sucks. If you have a tolerance to pain meds you will NOT die!
I find it sad that people just want to abuse these medications. I have terrible nerve damage that has led to RSD/CRPS (Complex Regional Pain Syndrome) as well as MS. As a 21 year old you couldn't begin to imagine the hoops I have had to jump through to get the correct pain medications because so many people abuse their pain meds. I am on Opana er which by the way is specially made so people cannot abuse it. It contains a silicate I believe so when anything liquid or moisture it turns into a very thick gel almost like liquid nails.Thus making Opana virtually impossible to abuse, when snorted it gels in your sinuses etc. Also there is no way that you could inject iv. I know this because as a Psych Major I like to educate others about the dangers of these types of medications. I am also on a fairly moderate dose of roxicodone. The point is, when so many people abuse pain medications it makes it harder for people like myself to get the medication I need, thank god for my pain doctor but I had to pretty much sign my life away to get the medication. There is a huge difference between abuse and need. I cannot make it through the day without my medication and am on crutches until the day comes that I will require a wheelchair. Anyways I just find it upsetting that because of people who abuse narcotic medications people who really truly need them have such a hard time getting them. Its even worse that some of you have doctors that don't mind to give you tons and tons of pills when there are ways to control pain without scripts of hundreds of pills, granted some people need them but that should solely NEED them to manage their pain. And to those of you with doctors that are loose with their prescription pads should have their medical license's taken away. They are just adding to the drug abuse epidemic. Just remember when you abuse medication it makes it that much harder for someone like me to receive their essential medications.
Storm

Seneca, SC

#13 May 29, 2011
First of all the ppl on here talking about ppl who prefer to snort pills than take them and s at ayin we are what makes it hard for ppl that are in pain to get em shut up ppl like yall are who I buy my pills from but about the exalgo I had a very hard time breakimg it down I took a sharp knife and cut it 4 quarters then crushed all of it with a zippo both parts.white.n gray like 30min agoand I feel.like I done a.30mg opana so I guess thhere good :) n bout the opanas there.is a wayto abuse them I live in nc inthe xoumtry n more than half this resnexks shpot the IR tens n fives and snort all the ers because obvioualy it.doesnt gel on ur nose but.the drainge that comes up the.throat is gel,
Storm

Seneca, SC

#14 May 29, 2011
And if yall didnt notice I was talkin to polaris princess no offense but ur bein a hypocrite cause ur prob high everday and lovein it and maybe u sould try snortin one of urs ull love it and u said ppl like us n blahblah well ppl like u are the ones who make us pillheads ik whwre u live but I live in lexington nc the ppl here pay ten to twenty dollars over the mg for opanas ive seen ag uy personal pay 70for a 40mg, crazzzyyy. But all im sayin is quit bein a hypoxritits called suply n demand ppl like u polarid supply ppl li ke me demand and make ppl like u richhh. Or I make my suppliers rich at least. Get at me on facebook anybody if u wanna tal sum deals like up storm kinley or kinley1322@yahoo.com :) lol not jokimg
M5Rules

Topeka, KS

#15 Jun 10, 2011
I have been on 400mg of Oxy a day for several years now due to back pain. I have always had a very high tolorence to pain meds (including novacain at the dentist) and a low tolerence to pain. I started on exalgo taking 6-16mg 1 X per day, and it was increased to the maximum the Doc felt comfortable with of 8-16mg per day. I do pretty much get releaf from that, but I still prefer the 2-80's and 1-40mg 2 X per day, because I can take them whenever they are needed, and don't have to wait 8 hours for the exalgo to kick in. I have not gotten any kind of "buzz" from the exalgo. The only thing I got out of taking 2 more then perscribed was total pain releif, and any more then 10 per day made me nasious, which was no fun. My main complaint is that on my dosage of 8 - 16mg per day costs me near $5,000 per month, compared to the 400mg Oxy is $1,800 mo. Doc wanted me to go on Methadone, but I'm very reluctant after going into a-Fib 2 x in the last 3 years. I'm curious as to other's thoughts.
manic

Forest, VA

#16 Jul 17, 2011
I am prescribed 16mg exalgo a day (2 8mg pills to be taken at the same time).
Cut them with a pill splitter. Scrape off the pink shell. Using a box cutter or exacto knife, cut the grey part off. Discard the grey stuff. The white stuff left over is pure hydromorphone. Dilaudid. It's not as much of a buzz as oxy, but it will give you lots of energy and keep you mellow at the same time if that makes sense. If you are not a long-time, heavy duty opiate user, DO NOT do this! Unless you want to stop breathing.
Bobby

Auburn, MA

#17 Jul 19, 2011
If you are a writer.... All you write in is you're diary. You are terrible. Go inspire and pop some more Opana. Wenth

Since: Jul 11

Cordele, GA

#18 Jul 19, 2011
When people are talking about cutting the Exalgo, they must be a heavy opiate user... describe heavy. Dr. recently just put me onto this 1 8mg x day. 2 of these a day dont seem to faze me in the least bit. But previously I was only on norco and vicadin... and was taking those very very heavily.
missy

Astoria, NY

#19 Sep 20, 2011
its gonna be my first time taking exalago im curious on how its gonna make me feel i dont like the feeling of being high is this a pain med that makes you feel high
ca_lynn

Newark, NJ

#20 Sep 25, 2011
Dr. Just switched me from 20mg Opana 2x/day, to the 8mg Exalgo 3x/day... Before this I was up to Oxyxodone 30mg- 4x/day..which is when she added the Opanas for extended release, in hopes of decreasing need for the oxy... Adding the Opanas didn't seem to add any pain relief, so, after September being 'pain management awarenesss month' and having more training updates/classes, seminars, etc, she switched me to Exalgo and cut my oxys down to 15mg (wench!) 4x/day...only thing she told me about the Exalgo was that "people don't like em cuz they don't get you high"..and "they hit different receptors in the brain"... I'm not sure what to think at the moment... I was thinking she should of just raised my Opana mg, but guess she, likes to yo-yo everyone's meds without concern for withdrawals, which ticks me off more than anything. I have a high tolerance to narcotic meds; used to be on 2 80mg Oxys/day with previous doc (who got shut down for writing too many meds).. now I'm reading previous posts saying some are taking 400/mg of Opanas/day, 16 Exalgos/day..damn, more than I would even try to take, and at one point I was so addicted to Oxy that I was 'taking' 10 80s a day, and no, not orally as directed.. anyway, my question to all u guys is this- anyone taking the Exalgo (who has opiate tolerance) have chest tightening as an effect? I went to Em.Room few nights ago- they did ekg and it was fine...just wondering if the Exalgo could be doing it..??
Rosally

Lambertville, NJ

#21 Sep 26, 2011
M5Rules wrote:
I have been on 400mg of Oxy a day for several years now due to back pain. I have always had a very high tolorence to pain meds (including novacain at the dentist) and a low tolerence to pain. I started on exalgo taking 6-16mg 1 X per day, and it was increased to the maximum the Doc felt comfortable with of 8-16mg per day. I do pretty much get releaf from that, but I still prefer the 2-80's and 1-40mg 2 X per day, because I can take them whenever they are needed, and don't have to wait 8 hours for the exalgo to kick in. I have not gotten any kind of "buzz" from the exalgo. The only thing I got out of taking 2 more then perscribed was total pain releif, and any more then 10 per day made me nasious, which was no fun. My main complaint is that on my dosage of 8 - 16mg per day costs me near $5,000 per month, compared to the 400mg Oxy is $1,800 mo. Doc wanted me to go on Methadone, but I'm very reluctant after going into a-Fib 2 x in the last 3 years. I'm curious as to other's thoughts.
I have been in pain management for three years after a car accident left me with daily, severe chronic pain. For the past year, I have been on mostly methadone -- 100 mg per day for a 125 lb young woman -- with 40 mg dilaudid for breakthrough (or actually flare-up of the constant pain) everyday and a few other nerve-pain non narcotic drugs.(on really bad days I snort dilaudid, or go to the doc to get it IV'd) The methadone is the best pain med in terms of low side effects for me. Oxycotin took the pain away well, but I got side effects like headache and nausea from it. I would try the methadone if your doc recommends it, as long as you have something for breakthrough pain. Dilaudid for me is the best for breakthrough, esp IV, though the doc has me trying exalgo now (though can't get it any local pharmacies for a week!)

Good luck!
backpain T

Monett, MO

#22 Oct 16, 2011
Rosally wrote:
<quoted text>
I have been in pain management for three years after a car accident left me with daily, severe chronic pain. For the past year, I have been on mostly methadone -- 100 mg per day for a 125 lb young woman -- with 40 mg dilaudid for breakthrough (or actually flare-up of the constant pain) everyday and a few other nerve-pain non narcotic drugs.(on really bad days I snort dilaudid, or go to the doc to get it IV'd) The methadone is the best pain med in terms of low side effects for me. Oxycotin took the pain away well, but I got side effects like headache and nausea from it. I would try the methadone if your doc recommends it, as long as you have something for breakthrough pain. Dilaudid for me is the best for breakthrough, esp IV, though the doc has me trying exalgo now (though can't get it any local pharmacies for a week!)
Good luck!
I too am a new used of Exalgo going from 80 to 100 mg Norco /day. trying to cut down the amount of pills and make it easier for pain relief, but he 3 exalgo a day are not cutting it. i still have the 10 mg Norco for back up but still taking 80 mg or norco with the 24 mg of exalgo, notice SMALL difference in that the Exalo makes the Norco last a bit longer, but need to up the dose of exalgo to cut out the 10 extra pills a day problem. my job situation cannot support an every 3 hour dose, so trying the extended release. Wondering if Opana is stronger than Exalgo and yep i know one is oxymorph and the other is hydromorph (dilaudid). Never experienced chest pain tho, tht could be panic, ihave valium and xanax for ms relas and panic.

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