Down Syndrome cured?

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Really

Ankeny, IA

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Jul 17, 2013
 

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Scientists find way to silence extra chromosome that causes Down syndrome

For patients suffering from Down syndrome, the source of their condition can be traced back to just one extra chromosome inherited during development – chromosome 21.

While it is still unclear exactly how this extra copy causes the symptoms of Down syndrome – also known as trisomy 21, its presence in a person’s genetic code is associated with delayed cognitive ability, slowed physical development and a whole host of health conditions, including congenital heart disease, cancer and early on-set Alzheimer’s.

But now, researchers say they have found a way to turn off the extra copy of chromosome 21.

In a new study published online in the journal Nature, scientists from University of Massachusetts Medical School (UMMS) harnessed the abilities of a naturally occurring gene called XIST that acts as an “off switch” in X chromosomes. In a culture of stem cells, the researchers were able to repurpose the XIST gene so that instead of silencing X chromosomes, it silenced the extra chromosome 21 instead.

Though the research only shows proof-of-principle for turning off the chromosome – meaning the method is a long way from being utilized in humans – the findings have huge implications for the future of Down syndrome research. Researchers hope this study will pave the way for a better understanding of the disorder’s pathology and potentially help to create new therapeutic targets for therapies.

“This is the beginning of this idea, and we’re hoping more investigators get interested,” lead researcher Jeanne Lawrence, professor of cell and developmental biology at UMMS, told FoxNews.com .“… We used epigenetics, a new concept, to change the way the DNA is expressed, not changing the DNA itself. This could have a lot of promise in other ways for Down syndrome and other disorders.”

Read more: http://www.foxnews.com/health/2013/07/17/scie...
Bushwhack r

Kent, WA

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Jul 17, 2013
 

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Maybe, you'll become a real boi....
Bushwhack r

Saint Paul, MN

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Jul 17, 2013
 

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Bushwhack r wrote:
Maybe, you'll become a real boi....
Good news! There is a cure for you.
Bushwhacker

Kent, WA

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Jul 17, 2013
 

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Now, I know where dojo $$$$$ came from.... Downs dummy doesn't get REAL MONEY.... LMAOROTFU~!
Bushwacker

Russia

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#6
Jul 18, 2013
 

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Bushwhack r wrote:
Maybe, you'll become a real boi....
And you know how I like the boi's.
Bushwacker

Russia

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Jul 18, 2013
 

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Why are my eyes so far apart?

“GiveMe Liberty or GiveMe Death”

Since: Jun 13

Land of Liberty

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#8
Jul 18, 2013
 

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Bushwhack r wrote:
Maybe, you'll become a real boi....
You need to stay away from children, no matter what you call them...... sick creep
Bob

Ashburn, VA

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#10
Jul 18, 2013
 
Bushwhacker wrote:
Sick retread....
Hey gay eye.
Bushwhacker

Kent, WA

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Jul 18, 2013
 

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Hello, buggered bragger....
Bushwhacker

Kent, WA

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#14
Jul 18, 2013
 

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Hello, buggered bragger....

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