Carbapenem-resistant Enterobacteriaceae

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DSM Local

Ankeny, IA

#2 Mar 6, 2013
Here’s what the CDC announced Tuesday:

•Healthcare institutions in 42 states have now identified at least one case of CRE.

•The occurrence of this resistance in the overall family of bacteria has risen at least four-fold over 10 years.

•In the CDC’s surveillance networks, 4.6 percent of hospitals and 17.8 percent of long-term care facilities diagnosed this bug in the first half of 2012.

Those are dire reports.
DSM Local

Ankeny, IA

#3 Mar 6, 2013
Carbapenems are a “last-resort” family of antibiotics — imipenem, meropenem, doripenem and ertapenem — which are used against these bacteria when they have become resistant to other drugs.(Carbapenem resistance is conferred by a number of different genes and so sometimes goes by a number of other acronyms, including KPC, VIM, OXA and the “Indian superbug” NDM-1.) In other words if you are on them, STAY ON THEM TILL YOU ARE TOLD OTHERWISE, or get sick next time or (more likely watch the same issue come back in DAYS) and DIE!
DSM Local

Ankeny, IA

#4 Mar 6, 2013
CRE-infected patient

2011
-1 patient - 1 facility

2012 first HALF (more idiots in the world more chances)
-200 hospitals and long-term acute-care facilities in 42 states treat at LEAST one CRE

Furthermore this is underreported because; CRE is not what public health calls a “reportable disease”; according to the CDC, only six states require that physicians or hospitals tell the rest of the world they have diagnosed it.(Three others are “considering” making it reportable.) And also, there are carbapenem-resistant bacteria causing outbreaks in the US which are not counted as CREs because the bacteria are not Enterobacteriaceae.
DSM Local

Ankeny, IA

#5 Mar 6, 2013
The tone of the CDC press conference yesterday was unusually somber and blunt. Frieden said:

CRE… pose a triple threat. First, they’re resistant to all or nearly all antibiotics. Even some of our last-resort drugs. Second, they have high mortality rates. They kill up to half of people who get serious infections with them. And third, they can spread their resistance to other bacteria. So one form of bacteria, for example, carbapenem-resistant Klebsiella, can spread the genes that destroy our last antibiotics to other bacteria, such as E. coli, and make E. coli resistant to those antibiotics also… We only have a limited window of opportunity.
DSM Local

Ankeny, IA

#6 Mar 6, 2013
What if this spread to like E.coli they are both GNB and reside in the intestines, UTI's & E. coli....... imagine if you had to flip a quarter to decide if you would survive your next UTI... now that is a nightmare
DSM Local

Ankeny, IA

#7 Mar 6, 2013
The cdc report on this is fascinating
http://www.cdc.gov/mmwr/preview/mmwrhtml/mm62...
CRASSUS

Green Bay, WI

#8 Mar 6, 2013
We should be damm happy to have a new bacteria around to thin out the herd. Due to advances in healthcare we are unlikely to see a flu pandemic like the Spanish flu which killed about 100 million people. We need some new viruses too. There is about 6 billion to many people on the planet right now.
DSM Local

Ankeny, IA

#9 Mar 6, 2013
For you people here on Topix I just want to recommend that you take your antibiotics full term and always wash your hands around medical settings and people who go there for whatever reason. Furthermore if you or a family member are in the hospital watch if the phlebotomist, nurse, and yes even doctor have actually washed (or used the foam stuff by the door); if not it is perfectly OKAY to say hey can you wash your hands for me. You do not want a nosocomial(hospital acquired) infection, which includes bacteria resistant to carbapenem. The natural resistant stuff like Stenotrophomonas maltophilia(also resistant to carbapenems) can still be treated for the sake of this example with co-trimoxazole and ticarcillin, but even this is waning and this is a nosocomial infection that has NOT mutated like Enterobacter.

The only reason this stuff like VRSA and CRE even exists is because doctors over prescribed, stupid people didn't go full term, and nosocomial infection. Don't become a case.
DSM Local

Ankeny, IA

#10 Mar 6, 2013
CRASSUS wrote:
We should be damm happy to have a new bacteria around to thin out the herd. Due to advances in healthcare we are unlikely to see a flu pandemic like the Spanish flu which killed about 100 million people. We need some new viruses too. There is about 6 billion to many people on the planet right now.
You're disgusting. In your case go play in the E.R.
CRASSUS

Green Bay, WI

#11 Mar 6, 2013
DSM Local wrote:
<quoted text>
You're disgusting. In your case go play in the E.R.
That's the same way I feel about you. Anyone who want world population to continue to explode is an idiot. Or in your case, just plain stupid.
DSM Local

Ankeny, IA

#12 Mar 6, 2013
CRASSUS wrote:
<quoted text>That's the same way I feel about you. Anyone who want world population to continue to explode is an idiot. Or in your case, just plain stupid.
I would prefer new and effective antibiotics be made. We are running out of what you refer to as "lines"

I hope you get pneumonia and face the growing resistance to Carbapenems and Third-Generation Cephalosporins among Clinical Isolates of Klebsiella pneumoniae in the United Staes in which you live.

FACT: USA has a urgent need to develop drugs active against Gram-negative bacteria.
DSM Local

Ankeny, IA

#13 Mar 6, 2013
There are older antibiotics we can use to treat this SOMETIMES (still over 50% FATAL) even when they work you still have to eal with thehigh kidney toxicity.
CRASSUS

Green Bay, WI

#14 Mar 6, 2013
DSM Local wrote:
<quoted text>
I would prefer new and effective antibiotics be made. We are running out of what you refer to as "lines"
I hope you get pneumonia and face the growing resistance to Carbapenems and Third-Generation Cephalosporins among Clinical Isolates of Klebsiella pneumoniae in the United Staes in which you live.
FACT: USA has a urgent need to develop drugs active against Gram-negative bacteria.
I'm hoping you get an infectious dose of Filoviridae with a side of Necrotizing fasciitis just for fun.
DSM Local

Ankeny, IA

#15 Mar 6, 2013
CRASSUS wrote:
<quoted text>I'm hoping you get an infectious dose of Filoviridae with a side of Necrotizing fasciitis just for fun.
necrotizing fascitis is a sypmtom not a organism, what do you hope causes, do tell
DSM Local

Ankeny, IA

#16 Mar 6, 2013
DSM Local wrote:
<quoted text>
necrotizing fascitis is a sypmtom not a organism, what do you hope causes, do tell
I hope CRASSUS gets it from Strep A
CRASSUS

Green Bay, WI

#17 Mar 6, 2013
DSM Local wrote:
<quoted text>
necrotizing fascitis is a sypmtom not a organism, what do you hope causes, do tell
It's an infection often caused by Streptococcus pyogenes. If someone has an unprotected deep tissue wound and some pinhead like you with strep throat coughs on it, necrotizing fasciitis develops. Don't try and talk microbiology smack with me punk, I aced that class. Maybe if you didn't spend all your time watching J ball, you would have achieved something. Like an education.
http://images.sciencedaily.com/2007/08/070815...
BTW calling an infection a Symptom is an example of how of how uneducated you are. You can't even look something simple up and figure out what it means.
CRASSUS

Green Bay, WI

#18 Mar 6, 2013
DSM Local wrote:
<quoted text>
I hope CRASSUS gets it from Strep A
You're throwing darts pinhead.
DSM Local

Ankeny, IA

#19 Mar 6, 2013
CRASSUS wrote:
<quoted text>It's an infection often caused by Streptococcus pyogenes. If someone has an unprotected deep tissue wound and some pinhead like you with strep throat coughs on it, necrotizing fasciitis develops. Don't try and talk microbiology smack with me punk, I aced that class. Maybe if you didn't spend all your time watching J ball, you would have achieved something. Like an education.
http://images.sciencedaily.com/2007/08/070815...
BTW calling an infection a Symptom is an example of how of how uneducated you are. You can't even look something simple up and figure out what it means.
S. pyogenes a.k.a. Strep A / like agalaticae is B ... idiot.

S. pyogenes is the pathogen anything it causes is a symptom of the infection ( invasion of a host organism's bodily tissues by disease-causing organisms)

this usually causes strep throat or potentialy Cellulitis, which may become complicated by necrotizing fascitis.... Someone coughing on you usually is not enough. dumbasz

Heavy doses of penicillin and clindamycin for 24 hours should clean it up.

If your so fing smart tell me how to ID it (presumptive will do).(in a lab)
I'll post the answer in a bit.
CRASSUS

Green Bay, WI

#20 Mar 6, 2013
DSM Local wrote:
<quoted text>
S. pyogenes a.k.a. Strep A / like agalaticae is B ... idiot.
S. pyogenes is the pathogen anything it causes is a symptom of the infection ( invasion of a host organism's bodily tissues by disease-causing organisms)
this usually causes strep throat or potentialy Cellulitis, which may become complicated by necrotizing fascitis.... Someone coughing on you usually is not enough. dumbasz
Heavy doses of penicillin and clindamycin for 24 hours should clean it up.
If your so fing smart tell me how to ID it (presumptive will do).(in a lab)
I'll post the answer in a bit.
Don't waste my time idiot.
http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0...
Let me guess. Your source is wikipedia. Have you ever taken microbiology in college? If so, when?
DSM Local

Ankeny, IA

#21 Mar 6, 2013
Strep A

-GPC on a gram stain (slightly smaller than Staph)
Furthermore beta hemolytic, you'll notice the MAC has no growth
-Catalase it (neg/staph-micrococcus will be pos)
-PYR (positive-reddish/pinkish color)

BAM!!! solved b1tkh!

Now, you tell me how to ID haemophilus parainfluenzae, or did you community college not teach you that?

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